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Glutamine--Fructose-6-Phosphate Transaminase 1 Proteins (GFPT1)

GFPT1 encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. Additionally we are shipping Glutamine--Fructose-6-Phosphate Transaminase 1 Antibodies (38) and Glutamine--Fructose-6-Phosphate Transaminase 1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GFPT1 14583 P47856
GFPT1 297417 P82808
GFPT1 2673 Q06210
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Top Glutamine--Fructose-6-Phosphate Transaminase 1 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 50 μg Log in to see 16 Days
$382.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,976.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$388.93
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

GFPT1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human , ,
,

Top referenced Glutamine--Fructose-6-Phosphate Transaminase 1 Proteins

  1. Human GFPT1 Protein expressed in Escherichia coli (E. coli) - ABIN2003902 : Chou: Molecular therapeutic target for type-2 diabetes. in Journal of proteome research 2004 (PubMed)
    Show all 2 references for ABIN2003902

More Proteins for Glutamine--Fructose-6-Phosphate Transaminase 1 (GFPT1) Interaction Partners

Mouse (Murine) Glutamine--Fructose-6-Phosphate Transaminase 1 (GFPT1) interaction partners

  1. GFAT-1 plays a critical role in modulating adipogenesis

Human Glutamine--Fructose-6-Phosphate Transaminase 1 (GFPT1) interaction partners

  1. 3'-UTR mutation creates a microRNA target site in the GFPT1 gene of patients with congenital myasthenic syndrome

  2. Two GFPT1 untranslated mutations may cause limb-girdle myasthenia by reducing GFPT1 expression and ultimately impairing protein glycosylation.

  3. Inhibition of GFPT1 enzymatic activity or siRNA silencing of GFPT1 expression resulted in reduced AChR expression.

  4. The results found no correlation between end plate morphology and physiology or between genotype and phenotype in GFPT1-myasthenia.

  5. GFPT1 is the key enzyme in the hexosamine biosynthesis pathway. Mutations in GFPT1 cause defective glycosylation in the proteins of the neuromuscular junction.

  6. Downregulation of the GFPT1 is associated with neuromuscular transmission defect.

  7. An increased concentration of wild-type GFAT in mesangial cells is enhanced both TGF-beta1 (show TGFB1 Proteins) and fibronectin (show FN1 Proteins)

  8. Genetic variation in GFPT1 is unlikely to have a major impact on susceptibility to diabetic nephropathy.

  9. Variants in the GFPT1 gene show suggestive evidence of an association with diabetic nephropathy among African-American individuals, and increased GFPT1 gene expression may characterize Caucasian subjects with diabetic nephropathy.

  10. On the basis of the docking results, a binding pocket of human GFAT1 dimer for UDP-GlcNAc (show B3GNT3 Proteins) is defined.

Pig (Porcine) Glutamine--Fructose-6-Phosphate Transaminase 1 (GFPT1) interaction partners

  1. Data suggest that enzymes in hexosamine biosynthesis pathway and downstream protein O-GlcNAcylation are important for preimplantation development; these include Gfpt, Oga (O-GlcNAcase), and Ogt (O-GlcNAc transferase).

  2. cDNA sequence of the porcine GFAT1 gene was cloned and a GFAT1 splice variant (designed GFAT1-L) that contains a 54 bp insertion within the coding region, was identified.

Glutamine--Fructose-6-Phosphate Transaminase 1 (GFPT1) Protein Profile

Protein Summary

This gene encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. The product of this gene catalyzes the formation of glucosamine 6-phosphate.

Gene names and symbols associated with GFPT1

  • glutamine--fructose-6-phosphate transaminase 1 (GFPT1)
  • glutamine--fructose-6-phosphate transaminase 1 (gfpt1)
  • glutamine fructose-6-phosphate transaminase 1 (Gfpt1)
  • 2810423A18Rik protein
  • AI324119 protein
  • AI449986 protein
  • CMSTA1 protein
  • GFA protein
  • GFAT protein
  • GFAT 1 protein
  • GFAT1 protein
  • GFAT1m protein
  • GFPT protein
  • GFPT1L protein
  • MSLG protein

Protein level used designations for GFPT1

glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 , glutamine-fructose-6-phosphate transaminase 1 , glutamine--fructose-6-phosphate transaminase 1 , D-fructose-6-phosphate amidotransferase 1 , GFAT 1 , glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 , glutamine:fructose 6 phosphate amidotransferase 1 , glutamine:fructose-6-phosphate amidotransferase 1 , hexosephosphate aminotransferase 1 , glutamine fructose aminotransferase , glutamine-fructose-6-phosphate aminotransferase 1

GENE ID SPECIES
281779 Bos taurus
414702 Xenopus laevis
450203 Pan troglodytes
574376 Macaca mulatta
100550931 Meleagris gallopavo
14583 Mus musculus
297417 Rattus norvegicus
2673 Homo sapiens
419514 Gallus gallus
474624 Canis lupus familiaris
397209 Sus scrofa
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