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Glutaminyl-tRNA Synthetase (QARS) ELISA Kits

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Additionally we are shipping Glutaminyl-tRNA Synthetase Antibodies (28) and Glutaminyl-tRNA Synthetase Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human QARS QARS 5859 P47897
Anti-Mouse QARS QARS 97541  
Anti-Rat QARS QARS 290868  
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More ELISA Kits for Glutaminyl-tRNA Synthetase Interaction Partners

Human Glutaminyl-tRNA Synthetase (QARS) interaction partners

  1. Pathological mutations mapping in the N-terminal domain alter the domain structure, and decrease catalytic activity and stability of GlnRS, whereas missense mutations in the catalytic domain induce misfolding of the enzyme.

  2. Data indicate compound heterozygous mutations [c.169T>C (p.Tyr57His) and c.1485dup (p.Lys496*)] in QARS (show EPRS ELISA Kits), which encodes glutaminyl-tRNA synthetase (show EPRS ELISA Kits), in two siblings with early-onset epileptic encephalopathy (EOEE).

  3. interactions between the N-terminal domains of ArgRS (show RARS ELISA Kits) and AIMP1 (show AIMP1 ELISA Kits) are important for the catalytic and noncatalytic activities of ArgRS (show RARS ELISA Kits) and for the assembly of the higher-order MSC (show MSC ELISA Kits) protein complex with ArgRS (show RARS ELISA Kits)-GlnRS-AIMP1 (show AIMP1 ELISA Kits)

  4. results highlight the importance of QARS (show EPRS ELISA Kits) during brain development and that epilepsy due to impairment of QARS (show EPRS ELISA Kits) activity is unusually severe in comparison to other aminoacyl-tRNA synthetase disorders

  5. Data indicate that glutaminyl-tRNA synthetase (show EPRS ELISA Kits) splice variant GlnRSDeltaiABD was present in exosomes extruded from Jurkat cells and functional in protein synthesis.

Glutaminyl-tRNA Synthetase (QARS) Antigen Profile

Antigen Summary

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with QARS

  • Glutaminyl-tRNA synthetase (Aats-gln) antibody
  • glutaminyl-tRNA synthetase (qars) antibody
  • glutaminyl-tRNA synthetase (QARS) antibody
  • glutaminyl-tRNA synthetase (glnS) antibody
  • glutaminyl-tRNA synthetase (Tb09.160.3730) antibody
  • glutaminyl-tRNA synthetase (Mrub_1755) antibody
  • glutaminyl-tRNA synthetase (Arnit_2221) antibody
  • glutaminyl-tRNA synthetase (Mesil_1300) antibody
  • glutaminyl-tRNA synthetase (Slip_2326) antibody
  • glutaminyl-tRNA synthetase (Trad_2932) antibody
  • glutaminyl-tRNA synthetase (Spirs_1481) antibody
  • glutaminyl-tRNA synthetase (Deba_3249) antibody
  • glutaminyl-tRNA synthetase (Thicy_0683) antibody
  • glutaminyl-tRNA synthetase (Qars) antibody
  • 1110018N24Rik antibody
  • 1200016L19Rik antibody
  • Aast-g1n antibody
  • BcDNA:GH11673 antibody
  • C80286 antibody
  • CG10506 antibody
  • Dmel\\CG10506 antibody
  • EPRS antibody
  • glnRS antibody
  • l(3)05461 antibody
  • PRO2195 antibody
  • PSPTO3743 antibody
  • qars antibody
  • QRS antibody
  • zgc:56395 antibody

Protein level used designations for QARS

Aats-gln-PA , CG10506-PA , glutamyl-prolyl-tRNA synthetase , glutaminyl-tRNA synthetase , glutamine--tRNA ligase , glutamine-tRNA synthetase , glutamine-tRNA ligase

GENE ID SPECIES
45786 Drosophila melanogaster
394188 Danio rerio
476628 Canis lupus familiaris
708111 Macaca mulatta
743625 Pan troglodytes
768346 Gallus gallus
1169559 Shewanella oneidensis MR-1
1185411 Pseudomonas syringae pv. tomato str. DC3000
2688228 Geobacter sulfurreducens PCA
3660156 Trypanosoma brucei brucei strain 927/4 GUTat10.1
8879862 Meiothermus ruber DSM 1279
9172384 Arcobacter nitrofigilis DSM 7299
9250796 Meiothermus silvanus DSM 9946
9275145 Syntrophothermus lipocalidus DSM 12680
9281945 Truepera radiovictrix DSM 17093
9489570 Spirochaeta smaragdinae DSM 11293
9495736 Desulfarculus baarsii DSM 2075
10719502 Thioalkalimicrobium cyclicum ALM1
5859 Homo sapiens
97541 Mus musculus
290868 Rattus norvegicus
514586 Bos taurus
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