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Glutaminyl-tRNA Synthetase Proteins (QARS)

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Additionally we are shipping Glutaminyl-tRNA Synthetase Antibodies (28) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
QARS 5859 P47897
Mouse QARS QARS 97541  
Rat QARS QARS 290868  
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Top Glutaminyl-tRNA Synthetase Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

QARS Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for Glutaminyl-tRNA Synthetase (QARS) Interaction Partners

Human Glutaminyl-tRNA Synthetase (QARS) interaction partners

  1. Pathological mutations mapping in the N-terminal domain alter the domain structure, and decrease catalytic activity and stability of GlnRS, whereas missense mutations in the catalytic domain induce misfolding of the enzyme.

  2. Data indicate compound heterozygous mutations [c.169T>C (p.Tyr57His) and c.1485dup (p.Lys496*)] in QARS (show EPRS Proteins), which encodes glutaminyl-tRNA synthetase (show EPRS Proteins), in two siblings with early-onset epileptic encephalopathy (EOEE).

  3. interactions between the N-terminal domains of ArgRS (show RARS Proteins) and AIMP1 (show AIMP1 Proteins) are important for the catalytic and noncatalytic activities of ArgRS (show RARS Proteins) and for the assembly of the higher-order MSC (show MSC Proteins) protein complex with ArgRS (show RARS Proteins)-GlnRS-AIMP1 (show AIMP1 Proteins)

  4. results highlight the importance of QARS (show EPRS Proteins) during brain development and that epilepsy due to impairment of QARS (show EPRS Proteins) activity is unusually severe in comparison to other aminoacyl-tRNA synthetase disorders

  5. Data indicate that glutaminyl-tRNA synthetase (show EPRS Proteins) splice variant GlnRSDeltaiABD was present in exosomes extruded from Jurkat cells and functional in protein synthesis.

Glutaminyl-tRNA Synthetase (QARS) Protein Profile

Protein Summary

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with QARS

  • Glutaminyl-tRNA synthetase (Aats-gln)
  • glutaminyl-tRNA synthetase (qars)
  • glutaminyl-tRNA synthetase (QARS)
  • glutaminyl-tRNA synthetase (glnS)
  • glutaminyl-tRNA synthetase (Tb09.160.3730)
  • glutaminyl-tRNA synthetase (Mrub_1755)
  • glutaminyl-tRNA synthetase (Arnit_2221)
  • glutaminyl-tRNA synthetase (Mesil_1300)
  • glutaminyl-tRNA synthetase (Slip_2326)
  • glutaminyl-tRNA synthetase (Trad_2932)
  • glutaminyl-tRNA synthetase (Spirs_1481)
  • glutaminyl-tRNA synthetase (Deba_3249)
  • glutaminyl-tRNA synthetase (Thicy_0683)
  • glutaminyl-tRNA synthetase (Qars)
  • 1110018N24Rik protein
  • 1200016L19Rik protein
  • Aast-g1n protein
  • BcDNA:GH11673 protein
  • C80286 protein
  • CG10506 protein
  • Dmel\\CG10506 protein
  • EPRS protein
  • glnRS protein
  • l(3)05461 protein
  • PRO2195 protein
  • PSPTO3743 protein
  • qars protein
  • QRS protein
  • zgc:56395 protein

Protein level used designations for QARS

Aats-gln-PA , CG10506-PA , glutamyl-prolyl-tRNA synthetase , glutaminyl-tRNA synthetase , glutamine--tRNA ligase , glutamine-tRNA synthetase , glutamine-tRNA ligase

GENE ID SPECIES
45786 Drosophila melanogaster
394188 Danio rerio
476628 Canis lupus familiaris
708111 Macaca mulatta
743625 Pan troglodytes
768346 Gallus gallus
1169559 Shewanella oneidensis MR-1
1185411 Pseudomonas syringae pv. tomato str. DC3000
2688228 Geobacter sulfurreducens PCA
3660156 Trypanosoma brucei brucei strain 927/4 GUTat10.1
8879862 Meiothermus ruber DSM 1279
9172384 Arcobacter nitrofigilis DSM 7299
9250796 Meiothermus silvanus DSM 9946
9275145 Syntrophothermus lipocalidus DSM 12680
9281945 Truepera radiovictrix DSM 17093
9489570 Spirochaeta smaragdinae DSM 11293
9495736 Desulfarculus baarsii DSM 2075
10719502 Thioalkalimicrobium cyclicum ALM1
5859 Homo sapiens
97541 Mus musculus
290868 Rattus norvegicus
514586 Bos taurus
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