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ectoenzyme that selectively hydrolyzes acidic amino acid residues from the amino terminus of oligopeptides [RGD, Feb 2006].. Additionally we are shipping ENPEP Kits (11) and ENPEP Proteins (10) and many more products for this protein.
Showing 10 out of 128 products:
Mouse (Murine) Monoclonal ENPEP Primary Antibody for FACS - ABIN371045
Cooper, Mulvaney, Coutinho, Cazenave: A novel cell surface molecule on early B-lineage cells. in Nature 1986
Show all 11 references for ABIN371045
Chemical Monoclonal ENPEP Primary Antibody for ELISA (Capture), ELISPOT (Capture) - ABIN2661962
Lin, Taniuchi, Kitamura, Wang, Kearney, Watanabe, Cooper: T and B cell development in BP-1/6C3/aminopeptidase A-deficient mice. in Journal of immunology (Baltimore, Md. : 1950) 1998
Show all 9 references for ABIN2661962
Human Polyclonal ENPEP Primary Antibody for EIA, FACS - ABIN951244
Teranishi, Ishiguro, Hoshino, Noguchi, Kubota, Uemura: Evaluation of role of angiotensin III and aminopeptidases in prostate cancer cells. in The Prostate 2008
Show all 3 references for ABIN951244
Human Polyclonal ENPEP Primary Antibody for FACS, IHC (p) - ABIN656026
Kalsi, Kuo, Aliev, Alexander, McMichael, Patterson, Walsh, Zhao, Schuckit, Nurnberger, Edenberg, Kramer, Hesselbrock, Tischfield, Vladimirov, Prescott, Dick, Kendler, Riley: A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts. in Human molecular genetics 2010
Human Polyclonal ENPEP Primary Antibody for IHC, ELISA - ABIN185416
Malerba, Pignatti: A review of asthma genetics: gene expression studies and recent candidates. in Journal of applied genetics 2005
Study describes a zebrafish 2 kb glutamyl aminopeptidase (enpep) promoter fragment, and shows that it can drive gene expression specifically in the kidney during early and late development.
de-regulation of both PITX2 (show PITX2 Antibodies) and ENPEP could contribute to an increased risk of atrial fibrillation in carriers of disease-associated variants.
Demonstrate a novel role of APA in ANG-(1 (show ANGPT1 Antibodies)-7) metabolism and suggest that the upregulation of APA, which occurs after myocardial infarction, may deprive the heart of cardioprotective ANG-(1 (show ANGPT1 Antibodies)-7).
Ischemia-induced angiogenesis is impaired in APA-KO mice partly through decreased HIF-1alpha (show HIF1A Antibodies) stability by proteasomal degradation and subsequent suppression of HIF-1alpha (show HIF1A Antibodies)-driven target protein expression such as growth factors.
Replacement of active site residue glutamate (show GRIN1 Antibodies)-215 of aminopeptidase A with aspartate or alanine leads to a strong decrease in the rate of hydrolysis of the synthetic substrate alpha-L-glutamyl-beta-naphthylamide.
the C-terminal domain of aminopeptidase A acts as an intramolecular chaperone
Lack of angiotensin II conversion to angiotensin III increases water but not alcohol consumption in aminopeptidase A-deficient mice.Elevated central concentrations of the vasopressor octapeptide angiotensin (Ang) II (show AGT Antibodies) increase the water intake in mammals.
Results demonstrate a key role of Thr (show TRH Antibodies)-348 in substrate specificity of aminopeptidase A for N-terminal acidic amino acids by insuring the optimal positioning of the substrate during catalysis.
miR-125b acts as a tumor suppressor in breast tumorigenesis via its novel direct targets ENPEP, CK2-alpha, CCNJ, and MEGF9.
These results explain the calcium-modulated substrate specificity of APA in central hypertension regulation
There was no significant alteration in plasma APA activity in the patients with Chagas disease or dilated cardiomyopathies, as compared with that in health controls
Rieger syndrome with microdeletions including only the PITX2 (show PITX2 Antibodies) and ENPEP (glutamyl aminopeptidase) genes.
Data show that APA appears to be an essential enzyme in the control of blood pressure via degradation of Angiotensin II.
Data show that aminopeptidase A (APA) plays important roles in the regulation of blood pressure under both the physiological and pathological conditions.
Data show that brain aminopeptidases act upon Ang I (show AGT Antibodies), Ang II (show AGT Antibodies) and Ang III (show AGT Antibodies) in order to activate brain AT(1) receptors.
rare and common variation in ENPEP may contribute to the development of renal and hypertensive disorders and warrants further study
The presence of APA in several human brain nuclei sensitive to angiotensins and involved in blood pressure regulation suggests that APA in humans is an integral component of the brain renin (show REN Antibodies) angiotensin system.
A novel nonsense polymorphism in the aminopeptidase-a gene was associated with hypertension among postmenopausal women, and those with marginal calcium and vitamin D intake.
ectoenzyme that selectively hydrolyzes acidic amino acid residues from the amino terminus of oligopeptides
glutamyl aminopeptidase (aminopeptidase A)
, aminopeptidase A
, glutamyl aminopeptidase
, BP-1/6C3 antigen
, differentiation antigen gp160