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Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. Additionally we are shipping Glutamyl-TRNA(Gln) Amidotransferase, Subunit C Proteins (15) and Glutamyl-TRNA(Gln) Amidotransferase, Subunit C Antibodies (7) and many more products for this protein.
The mitochondrial defective phenotype provoked by the absence of gatA in human cells is confirmed by means of a deficient ability to grow when galactose is used as a carbon source.
Studies showed in vitro Gln-tRNA(Gln) formation catalyzed by the recombinant mtGluRS and hGatCAB.
Glutamyl-tRNA Gln amidotransferase subunit interference produces a strong defect in mitochondrial translation without affecting the stability of the newly synthesized proteins. .
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity).
glu-AdT subunit C
, glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
, glutamyl-tRNA(Gln) amidotransferase, subunit C homolog
, gatC-like protein
, GatC-like protein
, Glu-AdT subunit C