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Glutaredoxin Proteins (GLRX)

GLRX encodes a member of the glutaredoxin family. Additionally we are shipping Glutaredoxin Antibodies (19) and Glutaredoxin Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse GLRX GLRX 93692 Q9QUH0
Rat GLRX GLRX 64045 Q9ESH6
GLRX 2745 P35754
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Top Glutaredoxin Proteins at

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
Yeast Ricinus communis His tag   1 mg Log in to see 56 to 66 Days
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 3 to 4 Days
HOST_Escherichia coli (E. coli) Yeast Un-conjugated   10 μg Log in to see 6 to 11 Days

GLRX Proteins by Origin and Source

Origin Expressed in Conjugate

More Proteins for Glutaredoxin (GLRX) Interaction Partners

Mouse (Murine) Glutaredoxin (GLRX) interaction partners

  1. Prx2 (show PRRX2 Proteins) glutathionylation is a favorable reaction that can occur in cells under oxidative stress and may have a role in redox signaling. GSH/Grx1 (show GRX1 Proteins) provide an alternative mechanism to thioredoxin (show TXN Proteins) and thioredoxin reductase (show PRDX2 Proteins) for Prx2 (show PRRX2 Proteins) recycling.

  2. The temporal relationships of Glrx1 (show GRX1 Proteins) with protein S-glutathionylation, glutathione, and cytokines/chemokines were observed as dynamic changes in lungs with allergic airway inflammation

  3. Glutaredoxin 1 (show GRX1 Proteins) plays an important role in controlling epithelial cell responsiveness to IL-17A (show IL17A Proteins)

  4. Up-r (show GRX1 Proteins)egulated Glrx inhibits VEGF signaling by increa (show FLT1 Proteins)sed Flt1 causing impaired vascularization.

  5. S-glutathionylation of Fas (show FAS Proteins) in lung epithelium enhances epithelial apoptosis and clearance of P. aeruginosa. Glutaredoxin-1 (show GRX1 Proteins) impairs bacterial clearance and increases severity of pneumonia in association with deglutathionylation of Fas (show FAS Proteins).

  6. These data suggest that the overexpression of GRX1 (show GRX1 Proteins) could protect cardiomyocytes against NO-induced apoptosis, likely through the inhibition of the oxidative modification and the nuclear translocation of GAPDH (show GAPDH Proteins).

  7. we provide evidence that Grx1 (show GRX1 Proteins) has an important role in regulating cigarette smoke-induced lung inflammation which seems to diverge from its effects on total PSSG.

  8. Data show that glutaredoxin (show GRX1 Proteins) acts as a reductant for methionine sulfoxide reductases A and B (MsrA (show MSR1 Proteins) and MsrB (show MSRB2 Proteins)) with or without resolving cysteine.

  9. results are the first to demonstrate that Grx-1 (show GRX1 Proteins) induces angiogenesis and diminishes ventricular remodeling apparently through neovascularization mediated by Akt (show AKT1 Proteins), VEGF (show VEGFA Proteins), Ang-1 (show ANGPT1 Proteins) and NF-kappaB (show NFKB1 Proteins) as well as Bcl-2 (show BCL2 Proteins) and survivin (show BIRC5 Proteins)-mediated anti-apoptotic pathway

  10. These results showed that cigarette smoke can modulate glutaredoxin 1 (show GRX1 Proteins), not only at the expression level, but can also directly modify glutaredoxin 1 (show GRX1 Proteins) itself, decreasing its activity.

Human Glutaredoxin (GLRX) interaction partners

  1. The results demonstrate that the antiproliferative effect of NO is hampered by Trx1 (show MLL Proteins) and Grx1 (show GRX1 Proteins) and support the strategy of weakening the thiolic antioxidant defenses when designing new antitumoral therapies.

  2. Prx2 (show PRDX2 Proteins) glutathionylation is a favorable reaction that can occur in cells under oxidative stress and may have a role in redox signaling. GSH/Grx1 (show GRX1 Proteins) provide an alternative mechanism to thioredoxin (show TXN Proteins) and thioredoxin reductase (show PRDX5 Proteins) for Prx2 (show PRDX2 Proteins) recycling.

  3. Glutaredoxin 1 (show GRX1 Proteins) protects human retinal pigment epithelial cells from oxidative damage by preventing AKT (show AKT1 Proteins) glutathionylation.

  4. A new function for GRX1 (show GRX1 Proteins) in neuronal copper homeostasis and in protection from copper-mediated oxidative injury.

  5. Human Grx1 (show GRX1 Proteins) can catalyse reduction of Atox1 (show ATOX1 Proteins) by glutathione but only in the presence of Cu(I).

  6. Levels of GLRX (show GRX1 Proteins) in the cerebrospinal fluid increase significantly in the early stages of Alzheimer's disease.

  7. Glrx (show GRX1 Proteins) overexpression increased soluble VEGF receptor (show FLT1 Proteins) 1 (sFlt) in endothelial cells via NF-kappaB (show NFKB1 Proteins)-dependent Wnt5a (show WNT5A Proteins) production.

  8. Thioredoxin 1 is inactivated due to oxidation induced by peroxiredoxin under oxidative stress and reactivated by the glutaredoxin (show GRX1 Proteins) system.

  9. sputum glutaredoxin-1 (show GRX1 Proteins) may have a role in asthma, while protein S may have a role in better lung function

  10. Studies show that the glutaredoxin (show GRX1 Proteins) system with glutathione plays a backup role to keep oxidized thioredoxin 1 (Trx1 (show TXN Proteins)) reduced in cells with loss of thioredoxin reductase 1 (TrxR1 (show TXNRD1 Proteins)) activity.

Glutaredoxin (GLRX) Protein Profile

Protein Summary

This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.

Gene names and symbols associated with Glutaredoxin Proteins (GLRX)

  • glutaredoxin (Glrx)
  • glutaredoxin (thioltransferase) (Glrx)
  • glutaredoxin (thioltransferase) (GLRX)
  • C86710 protein
  • D13Wsu156e protein
  • Glrx1 protein
  • GRX protein
  • GRX1 protein
  • TTase protein

Protein level used designations for Glutaredoxin Proteins (GLRX)

TTase-1 , glutaredoxin (thioltransferase) , glutaredoxin 1 (thioltransferase) , glutaredoxin-1 , thioltransferase-1

93692 Mus musculus
64045 Rattus norvegicus
2745 Homo sapiens
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