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anti-Glutaredoxin 2 (GRX2) Antibodies

The protein encoded by GRX2 is a member of the glutaredoxin family of proteins, which maintain cellular thiol homeostasis. Additionally we are shipping Glutaredoxin 2 Proteins (22) and Glutaredoxin 2 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GRX2 51022 Q9NS18
GRX2 114022 Q6AXW1
GRX2 69367 Q923X4
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Top anti-Glutaredoxin 2 Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of GLRX2 antibody (C-term T135) (ABIN391468) in mouse cerebellum tissue lysates (35 µg/lane). GLRX2 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain reacted with GLRX2 Antibody (C-term T135), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Figure 3. Glutaredoxin-2 Antibody staining of Hela cells by Flow Cytometry (Bottom Histogram) compared to a Negative Control cell (Top Histogram). FITC-conjugated Goat-anti-Rabbit secondary antibodies were used for the analysis. Figure 2. Glutaredoxin-2 Antibody staining of Formalin-Fixed and Paraffin-Embedded Human brain. This antibody was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-GLRX2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human heart WB Suggested Anti-GLRX2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Human heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-Glutaredoxin 2 antibody, Western blotting Lane 1: Rat Testis Tissue Lysate Lane 2: HELA Cell Lysate Lane 3: U87 Cell Lysate Lane 4: NEU Cell Lysate Lane 5: JURKAT Cell Lysate Lane 6: MCF-7 Cell Lysate Anti-Glutaredoxin 2 antibody, IHC(P) IHC(P): Rat Brain Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μg Log in to see 8 to 10 Days
$463.83
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged GLRX2 is 0.1 ng/ml as a capture antibody. Western Blot detection against Immunogen (39.38 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB   400 μL Log in to see 8 to 10 Days
$463.83
Details
Human Rabbit Un-conjugated WB Western Blot showing GLRX2 antibody used at a concentration of 1-2 ug/ml to detect its target protein. 50 μg Log in to see 7 to 9 Days
$473.93
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (39.75 KDa) . 50 μL Log in to see 9 Days
$298.57
Details

GRX2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Glutaredoxin 2 Antibodies

  1. Human Polyclonal Glutaredoxin 2 Primary Antibody for FACS, IHC (p) - ABIN391468 : Lundberg, Johansson, Chandra, Enoksson, Jacobsson, Ljung, Johansson, Holmgren: Cloning and expression of a novel human glutaredoxin (Grx2) with mitochondrial and nuclear isoforms. in The Journal of biological chemistry 2001 (PubMed)
    Show all 3 references for ABIN391468

  2. Human Polyclonal Glutaredoxin 2 Primary Antibody for EIA, FACS - ABIN488111 : Gladyshev, Liu, Novoselov, Krysan, Sun, Kryukov, Kryukov, Lou: Identification and characterization of a new mammalian glutaredoxin (thioltransferase), Grx2. in The Journal of biological chemistry 2001 (PubMed)
    Show all 3 references for ABIN488111

More Antibodies against Glutaredoxin 2 Interaction Partners

Human Glutaredoxin 2 (GRX2) interaction partners

  1. Grx2 and Trx1 (show MLL Antibodies) contribute significantly to neuronal integrity and could be clinically relevant in neuronal damage following perinatal asphyxia and other neuronal disorders.

  2. The Grx2 system could help to keep Trx2 (show TXN2 Antibodies)/1 reduced during an oxidative stress, thereby contributing to the anti-apoptotic signaling.

  3. Grx2 thiol redox regulation is essential for vertebrate embryonic development

  4. Exchange of [2Fe-2S] centers between glutaredoxin 2 and the cluster scaffold protein (show HOMER1 Antibodies) ISU, supports a direct link for glutaredoxin 2 and glutathione involvement in ISU promoted Fe-S cluster biosynthesis.

  5. Both thioredoxin 2 (show TXN2 Antibodies) and glutaredoxin 2 contribute to the reduction of the mitochondrial 2-Cys (show DNAJC5 Antibodies) peroxiredoxin Prx3 (show PRDX3 Antibodies).

  6. Studies indicate that the mechanism of Grx2 protection against H(2)O(2)-induced apoptosis is likely associated with its ability to preserve complex I.

  7. results suggest an important role for glutaredoxin 2 in protection and recovery from oxidative stress

  8. Grx1 (show GRX1 Antibodies) and Grx2 were present in placenta extracts and in cell lysates prepared from tumor cell lines; however, the levels of Grx1 (show GRX1 Antibodies) were at least 20 times higher than those of Grx2; Grx2 was not detected in plasma from healthy blood donors

  9. Lung cells can synthesize Grx2 mRNA and protein.

  10. characterization of Grx2 as an iron-sulfur center-containing member of the thioredoxin (show TXN Antibodies) fold protein family

Mouse (Murine) Glutaredoxin 2 (GRX2) interaction partners

  1. Increasing Grx2a activity in macrophage mitochondria disrupts mitochondrial respiration and ATP production, but without affecting the proatherogenic potential of macrophages from LDL receptor (show LDLR Antibodies) knockout mice.

  2. Grx2 gene deletion altered the function of lens structural proteins through S-glutathionylation and also caused severe disturbance in mitochondrial function.

  3. The results suggest that Glrx2b enhances RANKL (show TNFSF11 Antibodies)-induced osteoclastogenesis via p38 (show CRK Antibodies) activation.

  4. Data indicate that glutaredoxin-2 (Grx2) plays a vital role in modulating mitochondrial metabolism in cardiac muscle, and Grx2 deficiency leads to pathology.

  5. Grx2 deactivates UCP3 (show UCP3 Antibodies) by glutathionylation.

  6. Grx2 has a function that protects cells against H(2)O(2)-induced injury via its peroxidase and dethiolase activities; particularly, Grx2 prevents complex I inactivation and preserves mitochondrial function.

  7. Immunohistochemical analysis revealed segment-specific alterations induced by the ischemic insult. Grx2, Prx3 (show PRDX3 Antibodies), and Prx6 (show PRDX6 Antibodies) were highly expressed in proximal tubule cells

  8. Both thioredoxin 2 (show TXN2 Antibodies) and glutaredoxin 2 contribute to the reduction of the mitochondrial 2-Cys (show DNAJC5 Antibodies) peroxiredoxin Prx3 (show PRDX3 Antibodies).

  9. Data indicate that glutaredoxin 2 plays a central role in the response of mitochondria to both redox signals and oxidative stress by facilitating the interplay between the mitochondrial glutathione pool and protein thiols.

  10. Glutaredoxin-2 expression increased in a murine model of high-fat diet-induced atherogenesis.

Glutaredoxin 2 (GRX2) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the glutaredoxin family of proteins, which maintain cellular thiol homeostasis. These proteins are thiol-disulfide oxidoreductases that use a glutathione-binding site and one or two active cysteines in their active site. This gene undergoes alternative splicing to produce multiple isoforms, one of which is ubiquitously expressed and localizes to mitochondria, where it functions in mitochondrial redox homeostasis and is important for the protection against and recovery from oxidative stress. Other isoforms, which have more restrictive expression patterns, show cytosolic and nuclear localization, and are thought to function in cellular differentiation and transformation, possibly with a role in tumor progression.

Gene names and symbols associated with anti-Glutaredoxin 2 (GRX2) Antibodies

  • glutaredoxin 2 (Grx2) (grxB) antibody
  • glutaredoxin Grx2 (grx2) antibody
  • glutaredoxin (grx-2) (grx-2) antibody
  • glutaredoxin 2 (GLRX2) antibody
  • glutaredoxin 2 (Glrx2) antibody
  • glutaredoxin 2 (thioltransferase) (Glrx2) antibody
  • 1700010P22Rik antibody
  • AI645710 antibody
  • CGI-133 antibody
  • ECK1049 antibody
  • Grx2 antibody
  • JW1051 antibody

Protein level used designations for anti-Glutaredoxin 2 (GRX2) Antibodies

glutaredoxin 2 (Grx2) , glutaredoxin Grx2 , glutaredoxin (grx-2) , bA101E13.1 (GRX2 glutaredoxin (thioltransferase) 2) , glutaredoxin 2 (thioltransferase) , glutaredoxin-2, mitochondrial

GENE ID SPECIES
7955106 Escherichia coli BW2952
8215931 Escherichia coli O157:H7 str. TW14359
946926 Escherichia coli str. K-12 substr. MG1655
8183352 Escherichia coli BL21(DE3)
8175830 Escherichia coli B str. REL606
2542807 Schizosaccharomyces pombe 972h-
1485374 Archaeoglobus fulgidus DSM 4304
51022 Homo sapiens
114022 Rattus norvegicus
513762 Bos taurus
100172258 Pongo abelii
478956 Canis lupus familiaris
69367 Mus musculus
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