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anti-Glutaryl-CoA Dehydrogenase (GCDH) Antibodies

The protein encoded by GCDH belongs to the acyl-CoA dehydrogenase family. Additionally we are shipping Glutaryl-CoA Dehydrogenase Proteins (15) and Glutaryl-CoA Dehydrogenase Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GCDH 2639 Q92947
GCDH 364975  
GCDH 270076 Q60759
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Top anti-Glutaryl-CoA Dehydrogenase Antibodies at antibodies-online.com

Showing 10 out of 59 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-GCDH Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB GCDH Antibody (C-term) (ABIN656829) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Dog Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue reacted with GCD / GCDH Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of GCDH (arrow) using GCD / GCDH Antibody (C-term) Cat.-No AP51799PU-N. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GCDH gene. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Dog Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Rat Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, WB GCDH antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Skeletal muscle cells (arrows) in Human Muscle. Magnification is at 400X GCDH antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml. Magnification is at 400X 100 μg Log in to see 3 to 4 Days
$388.93
Details

GCDH Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Glutaryl-CoA Dehydrogenase Antibodies

  1. Human Polyclonal GCDH Primary Antibody for EIA, IHC (p) - ABIN952474 : Park, Lim, Kim, Hwang, Kim, Kang, Cho, Park, Lee, Chae: Glutaric aciduria type 1 in Korea: report of two novel mutations. in Journal of Korean medical science 2010 (PubMed)
    Show all 5 references for ABIN952474

  2. Dog (Canine) Polyclonal GCDH Primary Antibody for IHC, WB - ABIN2781317 : Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. in Diagnostic microbiology and infectious disease 2006 (PubMed)
    Show all 2 references for ABIN2781317

  3. Human Polyclonal GCDH Primary Antibody for WB - ABIN2781324 : Rao, Albro, Dwyer, Frerman: Kinetic mechanism of glutaryl-CoA dehydrogenase. in Biochemistry 2007 (PubMed)

  4. Human Polyclonal GCDH Primary Antibody for IHC (p), WB - ABIN656829 : Ganesh, Zakai, van Rooij, Soranzo, Smith, Nalls, Chen, Kottgen, Glazer, Dehghan, Kuhnel, Aspelund, Yang, Tanaka, Jaffe, Bis, Verwoert, Teumer, Fox, Guralnik, Ehret, Rice, Felix, Rendon et al.: Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.... in Nature genetics 2009 (PubMed)

More Antibodies against Glutaryl-CoA Dehydrogenase Interaction Partners

Human Glutaryl-CoA Dehydrogenase (GCDH) interaction partners

  1. Mutations in GCDH gene observed in the present study indicate genetic heterogeneity in GCDH gene among South Indian population. No definite genotype-phenotype correlations were observed.

  2. Point mutation of GCDH gene is associated with glutaric academia type I.

  3. 29 GCDH mutations were identified in 23 glutaric aciduria type 1 patients, including 11 novel mutations

  4. Data indicate a homozygous c.1244-2A> C mutation of the glutaryl-CoA dehydrogenase (GCDH) gene in both patients.

  5. These cells displayed decreased levels of GCDH tetramer.

  6. Identification of GCDH gene mutations in four patients with glutaric academia type I.

  7. A homozygous, disease-segregating mutation (p.Val400Met) was identified in the glutaryl-CoA dehydrogenase (GCDH) gene at chromosome 19p13.

  8. physiological concentrations of flavin adenine dinucleotide resulted in a spectacular enhancement of the thermal stabilities of GCDH and prevented enzymatic activity loss

  9. GCDH gene mutations are identified in 8 patients with glutaric aciduria type I

  10. 12 glutaric aciduria type 1 patients were found homozygous for the same A293T mutation in the glutaryl-CoA dehydrogenase (GCDH) gene.

Mouse (Murine) Glutaryl-CoA Dehydrogenase (GCDH) interaction partners

  1. The data of this study indicate higher susceptibility of Gcdh(-/-) mice to excitotoxic damage.

  2. GCDH-defective astrocytes actively contribute to produce and accumulate GA and 3HGA when Lys (show LYZ Antibodies) catabolism is stressed

  3. L-pipecolate is a major degradation product from L-lysine in murine brain generated by alpha-deamination of this amino acid in Gcdh-deficient mouse model for glutaric aciduria type I.

  4. Data show that glutaryl-Coenzyme A dehydrogenase Gcdh(-/-) knockout mice display elevated levels of glutaric acid (GA) and 3-hydroxyglutaric acid (3-OHGA) but do not spontaneously develop striatal lesions.

  5. These results provide evidence that glutamate (show GRIN1 Antibodies) receptor and transporter expression is higher in Gcdh-/- mice.

  6. bioenergetic impairment may play an important role in the pathomechanisms underlying neurodegenerative changes in glutaryl-CoA dehydrogenase deficiency

  7. Data show that pathologic events in glutaryl-CoA dehydrogenase-deficient mice/glutaric acidemia type I begin in neurons while lysine accumulation in the immature brain allows increased glutaric acid production and age-dependent injury.

Glutaryl-CoA Dehydrogenase (GCDH) Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12.

Gene names and symbols associated with GCDH

  • glutaryl-CoA dehydrogenase (GCDH) antibody
  • glutaryl-CoA dehydrogenase (Gcdh) antibody
  • glutaryl-Coenzyme A dehydrogenase (gcdh) antibody
  • glutaryl-Coenzyme A dehydrogenase (Gcdh) antibody
  • 9030411L18 antibody
  • ACAD5 antibody
  • AI266902 antibody
  • D17825 antibody
  • GCD antibody
  • zgc:56505 antibody
  • zgc:77704 antibody

Protein level used designations for GCDH

glutaryl-CoA dehydrogenase, mitochondrial , glutaryl-Coenzyme A dehydrogenase , GCD

GENE ID SPECIES
2639 Homo sapiens
476696 Canis lupus familiaris
364975 Rattus norvegicus
506310 Bos taurus
393860 Danio rerio
270076 Mus musculus
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