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Glutathione Peroxidase 1 Proteins (GPX1)

GPX1 encodes a member of the glutathione peroxidase family. Additionally we are shipping Glutathione Peroxidase 1 Antibodies (163) and Glutathione Peroxidase 1 Kits (81) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GPX1 2876 P07203
GPX1 14775 P11352
GPX1 24404 P04041
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Top Glutathione Peroxidase 1 Proteins at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag   10 μg Log in to see 5 to 8 Days
$299.25
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Schizosaccharomyces pombe His tag   1 mg Log in to see 56 to 66 Days
$2,355.83
Details
Yeast Yeast His tag   1 mg Log in to see 56 to 66 Days
$2,383.33
Details
Yeast Schistosoma mansoni His tag   1 mg Log in to see 56 to 66 Days
$2,388.83
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$2,486.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,489.67
Details
Yeast Pan troglodytes His tag   1 mg Log in to see 56 to 66 Days
$2,489.67
Details

GPX1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Glutathione Peroxidase 1 (GPX1) Interaction Partners

Human Glutathione Peroxidase 1 (GPX1) interaction partners

  1. GPX1*Pro198Leu AND GPX3 (show GPX3 Proteins) rs2070593 as genetic risk markers for Italian asthmatic patients

  2. An increase in both SOD1 (show SOD1 Proteins) and GPx1 activity is involved in the protective effect of sulodexide on ischemic endothelial cells.

  3. In patients with chronic hepatitis C, the GPX1 Pro198Leu polymorphism, alone or combined with the CAT C-262T, was associated with high risk of fibrosis severity and hepatocellular carcinoma (HCC (show FAM126A Proteins)). In addition, GPX1 polymorphism was also associated with advanced stages of HCC (show FAM126A Proteins).

  4. No significant difference was found for NRAMP1 (show SLC11A1 Proteins) and hGPX1 gene polymorphisms associated with recurrence time.

  5. Experimental and clinical data support a role for GPx-1 in the pathogenesis of inflammatory bowel disease (IBD), authors propose that GPX1 is the most relevant gene within IBD locus 12.

  6. Findings demonstrated that miR (show MLXIP Proteins)-153 overexpression decreased radioresistance and stemness of GSCs through targeting Nrf-2 (show GABPA Proteins)/GPx1/ROS (show ROS1 Proteins) pathway.

  7. Pro198Leu and OGG1 (show OGG1 Proteins) Ser326Cys polymorphisms were not associated with panic disorder (PD) risk in Turkish patients; however, a gender-specific effect of GPX1 Pro198Leu C allele may be associated with PD development

  8. GPX1 polymorphism may be an important factor modifying oxidative stress response in breast cancer subjects.

  9. GPx1 rs1800668 polymorphism does not play a major role in sensitivity-related illnesses -related oxidative stress development.

  10. The minor T-allele of rs3448 of GPX1 was associated with kidney complications (incidences of microalbuminuria, renal events and ESRD) in patients with type 1 diabetes.

Mouse (Murine) Glutathione Peroxidase 1 (GPX1) interaction partners

  1. Plasmalogen enrichment via batyl alcohol supplementation attenuated atherosclerosis in ApoE (show APOE Proteins)- and ApoE (show APOE Proteins)/GPx1-deficient mice.

  2. Gpx1 expression in the mouse skeletal muscle can be altered by both exercise and dyslipidemia through changes in DNA methylation (show HELLS Proteins), leading to a fine regulation of free radical metabolism.

  3. our findings unveil a new metabolic role for Reg3beta in protein nitration and a new biosynthesis control of GPX1 by a completely "unrelated" regenerating protein, Reg3beta, via transcriptional activation of Scly (show SCLY Proteins)

  4. Rora (show RORA Proteins) induces the mRNA level of antioxidant enzymes, superoxide dismutase 2 (show SOD2 Proteins) and glutathione peroxidase 1, through the Rora (show RORA Proteins) response elements located in the upstream promoters of Sod2 (show SOD2 Proteins) and Gpx1.

  5. High-fat-fed Gpx1(-/-) mice also exhibited decreased hepatic steatosis and liver damage accompanied by decreased plasma insulin (show INS Proteins) and decreased glucose-induced insulin (show INS Proteins) secretion.

  6. we propose that ileocolitis in the DKO mice is caused by Nox1 (show NOX1 Proteins), which is induced by TNF (show TNF Proteins). The milder disease in female het-TKO (show MRPS12 Proteins) intestine is probably due to random or imprinted X-chromosome inactivation, which produces mosaic Nox1 (show NOX1 Proteins) expression.

  7. PD-linked mutations in Parkin (show PARK2 Proteins) and DJ-1 (show PARK7 Proteins) cause dysregulation of neurotransmitter systems beyond the nigrostriatal dopaminergic circuit especially in the context of Gpx1 deficiency.

  8. During early differentiation of embryonic stem (ES) cells, the quick degradation of GPx-1 was mediated by proteasome. Both knockdown of GPx-1 expression with shRNA and inhibiting GPx-1 activity by inhibitor led to the differentiation of ES cells.

  9. Data indicate that he macrophage-colony-stimulating factor (show CSF2 Proteins) (MCSF (show CSF1 Proteins)) and oxLDL-induced proliferation of peritoneal macrophages from GPx-1(-/-)ApoE (show APOE Proteins)(-/-) mice was mediated by the ERK1/2 (extracellular-signal regulated kinase 1/2 (show MAPK3 Proteins)) signaling pathway.

  10. The present study has sought to investigate the extent of vascular dysfunction and oxidant formation in glutathione peroxidase-1-deficient (GPx-1(-/-)) mice during the aging process with special emphasis on dysregulation of the endothelial NO synthase.

Cow (Bovine) Glutathione Peroxidase 1 (GPX1) interaction partners

  1. Studied the importance of selenium in bovine female reproductive function. Gene expression analysis revealed selenoprotein gene GPX1 was significantly up-regulated in large healthy follicles.

  2. did not find any significant inhibition of bovine GPx-1 by (S)- or (R)-misonidazole.

  3. Data indicate mRNA level and activity of GPx1 are regulated by level of selenium supplied to hepatocytes.

  4. homocysteine decreases GPx1 activity by altering the translational mechanism

  5. glutathione peroxidase-1 activity is decreased by aminoglycosides through interference with selenocysteine incorporation

Pig (Porcine) Glutathione Peroxidase 1 (GPX1) interaction partners

  1. GPx1 plays a key role in blocking the promotion of porcine circovirus type 2 replication

  2. The developmental expression of GPX1 and thioredoxin reductase during fetal development and the effect of maternal selenium consumption on the expression of these proteins are reported.

Glutathione Peroxidase 1 (GPX1) Protein Profile

Protein Summary

This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene names and symbols associated with GPX1

  • glutathione peroxidase 1 (GPX1)
  • glutathione peroxidase Gpx1 (gpx1)
  • glutathione peroxidase (GPX3)
  • glutathione peroxidase (PtrcGpx1_2)
  • glutathione peroxidase (GPX1)
  • glutathione peroxidase (gpx1)
  • glutathione peroxidase (gpx)
  • glutathione peroxidase (Gpx)
  • glutathione peroxidase 1 (gpx1)
  • glutathione peroxidase 1a (gpx1a)
  • glutathione peroxidase (PtrcGpx3_2)
  • glutathione peroxidase (btuE-1)
  • glutathione peroxidase (GPX2)
  • glutathione peroxidase 1 (Gpx1)
  • mucin-5AC (MUC5AC)
  • AI195024 protein
  • AL033363 protein
  • cb690 protein
  • CGPx protein
  • Gpx protein
  • GPx-1 protein
  • gpx1 protein
  • GPXD protein
  • GSHPx protein
  • GSHPx-1 protein
  • GSHPX1 protein
  • zgc:92737 protein
  • zgc:103683 protein

Protein level used designations for GPX1

glutathione peroxidase Gpx1 , glutathione peroxidase , putative glutathione peroxidase , glutathione peroxidase 1 , GPx-1 , GSHPx-1 , cellular glutathione peroxidase , selenium-dependent glutathione peroxidase 1 , cytosolic glutathione peroxidase

GENE ID SPECIES
100053396 Equus caballus
2540222 Schizosaccharomyces pombe 972h-
8241668 Micromonas sp. RCC299
7465427 Populus trichocarpa
8250229 Micromonas sp. RCC299
5718788 Chlamydomonas reinhardtii
7818501 Pseudomonas fluorescens SBW25
3198161 Synechococcus elongatus PCC 6301
3344863 Corynebacterium glutamicum ATCC 13032
5151251 Bradyrhizobium sp. BTAi1
692548 Bombyx mori
100190660 Taeniopygia guttata
548457 Xenopus (Silurana) tropicalis
706732 Macaca mulatta
352926 Danio rerio
5115538 Bradyrhizobium sp. ORS 278
7460887 Populus trichocarpa
7465857 Populus trichocarpa
4407399 Leptospira borgpetersenii serovar Hardjo-bovis str. L550
4411584 Leptospira borgpetersenii serovar Hardjo-bovis str. JB197
4839694 Scheffersomyces stipitis CBS 6054
8240721 Micromonas sp. RCC299
9449700 Corynebacterium pseudotuberculosis FRC41
10844497 Corynebacterium ulcerans BR-AD22
2876 Homo sapiens
14775 Mus musculus
24404 Rattus norvegicus
281209 Bos taurus
397403 Sus scrofa
100009258 Oryctolagus cuniculus
442961 Canis lupus familiaris
100729115 Cavia porcellus
100857115 Gallus gallus
100820742 Ovis aries
461015 Pan troglodytes
789503 Bos taurus
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