You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Glutathione Peroxidase 2 (GPX2) Antibodies

GPX2 is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Additionally we are shipping Glutathione Peroxidase 2 Kits (12) and Glutathione Peroxidase 2 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GPX2 14776 Q9JHC0
GPX2 29326  
GPX2 2877 P18283
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Glutathione Peroxidase 2 Antibodies at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN185424 staining (1µg/ml) of Human Prostate lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Dog Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-GPX2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate WB Suggested Anti-GPX2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: HepG2 cell lysate  GPX2 is supported by BioGPS gene expression data to be expressed in HepG2 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB Anti-Glutathione Peroxidase 2 antibody, ICC ICC: HELA Cell Anti-Glutathione Peroxidase 2 antibody, IHC(P) IHC(P): Rat Testis Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IP, IHC (p), WB IP Image Immunoprecipitation of GPX2 protein from HepG2 whole cell extracts using 5 μg of GPX2 antibody [C1C3], Western blot analysis was performed using GPX2 antibody [C1C3], EasyBlot anti-Rabbit IgG  was used as a secondary reagent. IHC-P Image Immunohistochemical analysis of paraffin-embedded human gastric cancer, using GPX2, antibody at 1:500 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemical analysis of paraffin-embedded Gastric ca, using GPX2 antibody at 1/500 dilution. Immunohistochemical analysis of paraffin-embedded Muscle, using GPX2 antibody at 1/500 dilution. 0.1 mL Log in to see 6 to 8 Days
$401.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN250547 staining (1?g/ml) of Human Prostate lysate (RIPA buffer, 30?g total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 0.1 mg Log in to see 5 to 7 Days
$427.88
Details
Human Rabbit Un-conjugated ICC, IHC, WB   100 μg Log in to see 8 to 10 Days
$463.83
Details

GPX2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
,

Rat (Rattus)
,

Human ,
,

, , , , ,

Top referenced anti-Glutathione Peroxidase 2 Antibodies

  1. Human Polyclonal Glutathione Peroxidase 2 Primary Antibody for ELISA, WB - ABIN185424 : Esworthy, Yang, Frankel, Chu: Epithelium-specific glutathione peroxidase, Gpx2, is involved in the prevention of intestinal inflammation in selenium-deficient mice. in The Journal of nutrition 2005 (PubMed)
    Show all 3 references for ABIN185424

  2. Dog (Canine) Polyclonal Glutathione Peroxidase 2 Primary Antibody for WB - ABIN374580 : Naiki-Ito, Asamoto, Hokaiwado, Takahashi, Yamashita, Tsuda, Ogawa, Shirai: Gpx2 is an overexpressed gene in rat breast cancers induced by three different chemical carcinogens. in Cancer research 2007 (PubMed)
    Show all 2 references for ABIN374580

More Antibodies against Glutathione Peroxidase 2 Interaction Partners

Rainbow Trout (Oncorhynchus mykiss) Glutathione Peroxidase 2 (GPX2) interaction partners

  1. The authors cloned cytosolic glutathione peroxidase (GPx1 (show GPX1 Antibodies)) and phospholipid hydroperoxide glutathione peroxidase (GPx4) genes in rainbow trout (Oncorhynchus mykiss). Constitutive mRNA expression and responsiveness to Se availability was analysed.

Mouse (Murine) Glutathione Peroxidase 2 (GPX2) interaction partners

  1. High glutathione peroxidase 2 expression is associated with radiation induced lung disease.

  2. we propose that ileocolitis in the GPx1 (show GPX1 Antibodies)/2-double-knockout mice is caused by Nox1 (show NOX1 Antibodies), which is induced by TNF (show TNF Antibodies)

  3. GPx2 is up-regulated in dysplastic colonic crypts, where it appears to act inhibit apoptosis and, thus, supports tumor development.

  4. Candidate colitis genes in the Gdac1 locus of mice deficient in glutathione peroxidase-1 (show GPX1 Antibodies) and -2, were analyzed.

  5. it is concluded that GPx2, although supporting tumor growth, inhibits inflammation-mediated tumorigenesis, but the protective effect of selenium does not strictly depend on GPx2 expression

  6. study indicates GI-GPx is spatiotemporally expressed in embryonic organs during organogenesis and may also perform a mutual compensatory role with cGPx (show GPX1 Antibodies) in protecting embryos and extraembryonic tissues against reactive oxygen species

  7. Loss of Gpx2 is associated with diet induced severe colitis.

  8. In GPx2 KO mice, an increase in GPx1 (show GPX1 Antibodies) can only partially compensate for GPx2, even under selenium supplementation, indicating that GPx2 is the major antiapoptotic GPx (show PRDX6 Antibodies) in the colon.

  9. Genes encoding the antioxidants GPX2 and GSTO 1-1 (show GSTO1 Antibodies) are common inflammatory genes expressed upon induction of allergic airway inflammation, and independently of allergic susceptibility.

  10. GPX1 (show GPX1 Antibodies)-DKO and GPX2-DKO mice are highly susceptible to bacteria-associated inflammation and cancer.

Human Glutathione Peroxidase 2 (GPX2) interaction partners

  1. GPX2 underexpression is associated with advanced tumor status and implicated unfavorable clinical outcome of UCs, suggesting its role in tumor progression and may serve as a theranostic biomarker of UCs.

  2. high GPx2 expression was associated with early tumor recurrence, particularly in the recently identified aggressive subtype of human colon cancer.

  3. Patients with high GPX2 expression in biopsy specimen had significantly lower prostate-specific antigen (show KLK3 Antibodies) recurrence-free survival and overall survival than those with no GPX2 expression.

  4. miR (show MLXIP Antibodies)-185 plays a role in up-regulation of GPX2 and SEPHS2 (show SEPHS2 Antibodies) expression.

  5. A role of GPx2, TrxR2 (show TXNRD2 Antibodies) and TrxR3 (show TXNRD3 Antibodies) in proliferation, apoptosis and, therefore, also during cancer development.

  6. A GPx2-independent decrease in tumor development by selenium (Se) and detrimental effects of the Nrf2 (show GABPA Antibodies)-activator sulforaphane in moderate Se deficiency.

  7. Cellular and subcellular localization of gastrointestinal glutathione peroxidase in normal and malignant human intestinal tissue

  8. Data suggest that some antioxidants may exert their anti-inflammatory and anticarcinogenic effects not only by induction of phase 2 enzymes but also by the up-regulation of the selenoprotein GI-GPx by Nrf2 (show GABPA Antibodies) binding.

  9. some isoforms of p63 (show RPE65 Antibodies) serve as a pro-survival factor by up-regulating GPX2 to reduce the p53 (show TP53 Antibodies)-dependent oxidative stress-induced (show SQSTM1 Antibodies) apoptotic response

  10. Glutathione peroxidase 2 (GPX2) is the major oxidative stress-inducible cellular GPX (show GPX1 Antibodies) isoform in the lungs, and its basal as well as inducible expression is dependent on Nrf2 (show GABPA Antibodies).

Glutathione Peroxidase 2 (GPX2) Antigen Profile

Protein Summary

This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. The protein encoded by this locus contains a selenocysteine (Sec) residue encoded by the UGA codon, which normally signals translation termination. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with GPX2

  • glutathione peroxidase type 2 (LOC100136264) antibody
  • glutathione peroxidase 2 (gastrointestinal) (GPX2) antibody
  • glutathione peroxidase 2 (LELG_01052) antibody
  • glutathione peroxidase 2 (Gpx2) antibody
  • GI-GPx antibody
  • GPRP antibody
  • GPRP-2 antibody
  • GPx-2 antibody
  • GPX-GI antibody
  • GSHPx-2 antibody
  • GSHPX-GI antibody
  • LOC100136264 antibody

Protein level used designations for GPX2

glutathione peroxidase type 2 , glutathione peroxidase 2 , GPx-2 , glutathione peroxidase-gastrointestinal , intestinal GPx , gastrointestinal glutathione peroxidase , glutathione peroxidase-related protein 2

GENE ID SPECIES
100136264 Oncorhynchus mykiss
467483 Pan troglodytes
708429 Macaca mulatta
5234988 Lodderomyces elongisporus NRRL YB-4239
14776 Mus musculus
29326 Rattus norvegicus
2877 Homo sapiens
480356 Canis lupus familiaris
767625 Sus scrofa
533088 Bos taurus
Selected quality suppliers for anti-Glutathione Peroxidase 2 (GPX2) Antibodies
Did you look for something else?