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anti-Glutathione Reductase (GSR) Antibodies

GSR encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. Additionally we are shipping Glutathione Reductase Kits (49) and Glutathione Reductase Proteins (17) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GSR 2936 P00390
GSR 14782 P47791
GSR 116686  
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Top anti-Glutathione Reductase Antibodies at antibodies-online.com

Showing 10 out of 119 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-GSR Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Hela cell lysate WB Suggested Anti-GSR Antibody  Positive Control: Lane 1:141 µg untreated zebrafish head lysate Lane 2: 141 µg 3hr H2O2 treated zebrafish head lysate Lane 3: 141 µg 6hr H2O2 treated zebrafish head lysate Primary Antibody Dilution: 1:0000Secondary Antibody: Anti rabbit-HRP Secondry  Antibody Dilution: 1:00,000Submitted by: Dr. Yuk Fai Leung, Purdue University 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Confocal immunofluorescent analysis of GSR Antibody (C-term) (ABIN655985) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, FACS, IF, IHC (p), WB Flow cytometric analysis of NCI-H460 cells using Glutathione reductase Antibody (C-term) Cat.-No AP51963PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis. Confocal immunofluorescent analysis of Glutathione reductase Antibody (C-term) Cat.-No AP51963PU-N with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Arabidopsis thaliana Rabbit Un-conjugated IL, IP, WB 10 ug of total protein from (1) Arabidopsis thaliana leaf extracted with Protein Extration Buffer, PEB, (2) Nicotiana tabaccum leaf extracted with PEB, (3) Zea mays extracted with PEB, (4) Hordeum vulgare leaf extracted with PEB, (5) Physcomitrella patens total cell extracted with PEB, (6) Chlamydomonas reinhardtii total cell extracted with PEB,  (7) Synochocystis elongatus total cell extracted with PEB, extracted with PEB, were separated on  4-12% NuPage (Invitrogen) LDS-PAGE and blotted 1h to nitrocellulose. Blots were blocked in 2 % low fat dry milk in TBS-T (0.1 % Tween 20) for 1h at room temperature with agitation. Blots were incubated in the primary antibody at a dilution of 1: 2000 for 1h at room temperature with agitation. The antibody solution was decanted and the blot was rinsed briefly twice, then washed once for 15 min and 3 times for 5 min in TBS-T at room temperature with agitation. Blots were incubated in secondary antibody (anti-rabbit IgG horse radish peroxidase conjugated) diluted to 1:30 000 for 1h at room temperature with agitation. The blots were washed as above and developed for  30 seconds  with WEST PICO reagent according the manufacturers instructions. 100 μL Log in to see 5 to 6 Days
$473.55
Details
Human Mouse Un-conjugated IP, ELISA 100 μL Log in to see 2 to 3 Days
$367.50
Details
Human Rabbit Un-conjugated WB Figure 1. Glutathione Reductase antibody staining of HeLa whole cell lysate (30 µg) (Lane A) at 1/1000 dilution, 7.5% SDS PAGE. Figure 2. Glutathione Reductase antibody staining of HCT116 whole cell lysate (30 µg) (Lane A) at 1/1000 dilution, 7.5% SDS PAGE. 0.1 mL Log in to see 6 to 8 Days
$401.50
Details
Yeast Rabbit Biotin DB, EIA, ID, IF, IP, RIA, WB   1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Mouse Un-conjugated WB Western blot analysis of GSR over-expressed 293 cell line, cotransfected with GSR Validated Chimera RNAi used as specificity and loading control. Western Blot analysis of GSR expression in transfected 293T cell line by GSR monoclonal antibody (M01), clone 6B4. Lane 1: GSR transfected lysate(56.3 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-Glutathione Reductase antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN957790 dilution 1:400. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details

GSR Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus) , ,


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Top referenced anti-Glutathione Reductase Antibodies

  1. Arabidopsis thaliana Polyclonal Glutathione Reductase Primary Antibody for IL, IP - ABIN190699 : Sobrino-Plata, Ortega-Villasante, Flores-Cuaceres, Escobar, Del Campo, Hernuandez: Differential alterations of antioxidant defenses as bioindicators of mercury and cadmium toxicity in alfalfa. in Chemosphere 2009 (PubMed)
    Show all 4 references for ABIN190699

  2. Human Polyclonal Glutathione Reductase Primary Antibody for EIA, FACS - ABIN952543 : Satoh, Watanabe, Kanda, Sugaya-Fukasawa, Hisatomi: Expression of glutathione reductase splice variants in human tissues. in Biochemical genetics 2010 (PubMed)
    Show all 2 references for ABIN952543

  3. Cow (Bovine) Polyclonal Glutathione Reductase Primary Antibody for WB - ABIN2785662 : Senturk, Kufrevioglu, Ciftci: Effects of some antibiotics on human erythrocyte glutathione reductase: an in vitro study. in Journal of enzyme inhibition and medicinal chemistry 2008 (PubMed)

  4. Human Polyclonal Glutathione Reductase Primary Antibody for FACS, IF - ABIN655985 : Moyer, Sun, Batzler, Li, Schaid, Yang, Weinshilboum: Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy. in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010 (PubMed)

More Antibodies against Glutathione Reductase Interaction Partners

Fruit Fly (Drosophila melanogaster) Glutathione Reductase (GSR) interaction partners

  1. Molecular orbital calculations suggested that the C-terminal hexapeptide Pro-Ala-Ser (show SIGLEC1 Antibodies)-Cys-Cys (show DNAJC5 Antibodies)-Ser (show SIGLEC1 Antibodies)-OH functions as a redox center that alleviates the necessity for selenium in Dm-TrxR.

  2. analysis of the mechanism of high Mr thioredoxin reductase from Drosophila melanogaster

  3. changing of His106 to asparagine, glutamine, and phenylalanine in various C-terminal mutants of Drosophila melanogaster thioredoxin reductase drops catalytic activity without change in pH profile

  4. X-ray crystal structure of thioredoxin reductase at 2.4 A resolution; demonstrated that tetrapeptides equivalent to the oxidized C-terminal active sites of both mouse mitochondrial TR (mTR3 (show EXOSC6 Antibodies)) and DmTR are substrates for the truncated forms of both enzymes

  5. redox potentials provide direct evidence for proposed catalytic mechanism of DmTrxR, & cast new light on essential role of DmTrx system in cycling GSSG/GSH & maintaining intracellular redox homeostasis in D. melanogaster without glutathione reductase.

  6. rates of steps in both the reductive and the oxidative half-reactions are markedly diminished in H464'Q thioredoxin reductase as compared to those of wild-type enzyme, indicating that His-464' is involved in both half-reactions

  7. the role of Glu (show SLC2A1 Antibodies)-469' in catalysis by DmTrxR

Arabidopsis thaliana Glutathione Reductase (GSR) interaction partners

  1. Data indicate that glutathione reductase 2 (GR2) protects photosystem II (PSII) from excess light and maintains the function of acceptor side of PSII.

  2. Plastid-localized glutathione reductase-2-regulated glutathione redox status is essential for Arabidopsis root apical meristem maintenance.

Human Glutathione Reductase (GSR) interaction partners

  1. Plasma glutathione reductase (GR) activity was correlated with erythrocyte GR activity and the erythrocyte reduced glutathione/glutathione disulfide ratio. A decrease in plasma GR activity was associated with an increase in mortality in septic shock.

  2. Glutathione reductase reduces mitochondrial protein (show COX6B2 Antibodies) mitoNEET (show CISD1 Antibodies) [2Fe-2S] clusters.

  3. The recurrence of benign tumors of mammary gland occurred predominantly in women-carriers of mutant alleles with polymorphism rs8190924 of gene GSR and AA rs3763511of gene DKK4 (show DKK4 Antibodies).

  4. GSR was the most significant single SNP association with systemic lupus erythematosus in African Americans.

  5. 1,25 (OH) vitamin D significantly upregulated expression of GCLC (show GCLC Antibodies) and GR and lowered secretion of IL-8 (show IL8 Antibodies) and MCP-1 (show CCL2 Antibodies) in high-glucose exposed U937 monocytes.

  6. The results demonstrate for the first time that glutathione reductase gene polymorphisms are significantly associated with bone mineral density.

  7. Up-regulation of CAT and GR activity resulted in an increase in total antioxidant activity in A549 after exposure to B (show TDO2 Antibodies)(a)P.

  8. Human eye lenses were dissected into discrete regions that were formed at different stages of life and assayed for activity of lactate dehydrogenase (LDH) and a particularly stable enzyme, glutathione reductase (GR).

  9. novel glutathione reductase alternative splice variants

  10. Data show that decreased activities of GPX1 (show GPX1 Antibodies), increased activities of GR and CuZnSOD (show SOD1 Antibodies) in women with depressive disorder.

Mouse (Murine) Glutathione Reductase (GSR) interaction partners

  1. Data show that reducing RGS2 (show RGS2 Antibodies) expression by antisense treatment prevented the increase in GLO1 (show GLO1 Antibodies) and GSR1 mRNA and protein expression.

  2. Local overexpression in the mouse brain resulted in increased anxiety-like behaviour; Gsr is involved in oxidative stress metabolism, linking this pathway with anxiety-related behaviour

Cow (Bovine) Glutathione Reductase (GSR) interaction partners

  1. Liver biopsy is a valuable tool for detecting oxidative stress and for diagnosing hepatic dysfunction in cattle from glutathione and glutathione reductase levels.

Glutathione Reductase (GSR) Antigen Profile

Protein Summary

This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

Gene names and symbols associated with GSR

  • glutathione reductase, gro-2 (GR) antibody
  • glutathione reductase (gor) antibody
  • GR; GRase (gor) antibody
  • glutathione reductase (GR) antibody
  • glutathione reductase (GSR) antibody
  • glutathione reductase (PtrcGR1) antibody
  • glutathione reductase (GSR1) antibody
  • glutathione reductase (Gsr_2) antibody
  • glutathione reductase (GSHR1) antibody
  • glutathione reductase (gsr) antibody
  • glutathione reductase (LbGR) antibody
  • glutathione reductase (pgr1) antibody
  • glutathione reductase (GSHR2) antibody
  • Glutathione reductase (GR) (GRase) (GLR2) antibody
  • glutathione reductase (Bcen_2392) antibody
  • glutathione reductase (RPE_1989) antibody
  • glutathione reductase (HCAG_02219) antibody
  • glutathione reductase (SJAG_01162) antibody
  • Thioredoxin reductase-1 (Trxr-1) antibody
  • glutathione reductase (PF14_0192) antibody
  • glutathione reductase (PtrcGR2) antibody
  • glutathione reductase (Gsr) antibody
  • glutathione reductase1 (gsr1) antibody
  • gutter shaped root (Gusr) antibody
  • 2151 antibody
  • AI325518 antibody
  • anon-WO03040301.185 antibody
  • anon-WO03040301.187 antibody
  • ATGR2 antibody
  • CG2151 antibody
  • D8Ertd238e antibody
  • DDBDRAFT_0168952 antibody
  • DDBDRAFT_0231410 antibody
  • DDB_0168952 antibody
  • DDB_0231410 antibody
  • Dm-TrxR antibody
  • Dmel\\CG2151 antibody
  • DmTR antibody
  • DmTrx antibody
  • DmTrxR antibody
  • dmtrxr-1 antibody
  • DTR antibody
  • dTrxR antibody
  • EMB2360 antibody
  • glutathione reductase antibody
  • gor1 antibody
  • gr antibody
  • Gr-1 antibody
  • Gr1 antibody
  • GSR antibody
  • l(1)G0154 antibody
  • l(1)G0379 antibody
  • l(1)G0477 antibody
  • l(1)G0481 antibody
  • Trx antibody
  • TrxR antibody
  • trxr-1 antibody
  • Trxr1 antibody

Protein level used designations for GSR

glutathione reductase, gro-2 , glutathione reductase , glutathione reductase, mitochondrial , glutathione-disulfide reductase , Glutathione reductase (GR) (GRase) , CG2151-PA , CG2151-PB , CG2151-PC , Trxr-1-PA , Trxr-1-PB , Trxr-1-PC , disulfide reductase , thioredoxin reductase , thioredoxin reductase-1 , GR , GRase , glutathione reductase 1 , SOG0187 , csu111 , csuh111 , gsy308(gsr) , mGR , siAJ006055 , siAJ006055_ov , siaj006055(8) , siaj006055a , umc368

GENE ID SPECIES
7447802 Thalassiosira pseudonana CCMP1335
1052725 Bradyrhizobium diazoefficiens USDA 110
3429587 Haemophilus influenzae 86-028NP
547793 Glycine max
464099 Pan troglodytes
7462504 Populus trichocarpa
5000428 Ostreococcus lucimarinus CCE9901
7200844 Phaeodactylum tricornutum CCAP 1055/1
5722016 Chlamydomonas reinhardtii
8618618 Dictyostelium discoideum AX4
3092896 Burkholderia pseudomallei K96243
6074272 Laccaria bicolor S238N-H82
2540156 Schizosaccharomyces pombe 972h-
5720329 Chlamydomonas reinhardtii
4851989 Scheffersomyces stipitis CBS 6054
4092978 Burkholderia cenocepacia AU 1054
4359499 Rhodopseudomonas palustris BisA53
5448670 Ajellomyces capsulatus NAm1
7047421 Schizosaccharomyces japonicus yFS275
31760 Drosophila melanogaster
811773 Plasmodium falciparum 3D7
7496065 Populus trichocarpa
824631 Arabidopsis thaliana
2936 Homo sapiens
14782 Mus musculus
116686 Rattus norvegicus
396625 Sus scrofa
506406 Bos taurus
100718789 Cavia porcellus
475596 Canis lupus familiaris
771783 Gallus gallus
100393824 Callithrix jacchus
541986 Zea mays
109408 Mus musculus
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