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Glutathione Reductase Proteins (GSR)

GSR encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. Additionally we are shipping Glutathione Reductase Antibodies (119) and Glutathione Reductase Kits (49) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GSR 2936 P00390
GSR 14782 P47791
GSR 116686  
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Top Glutathione Reductase Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 50 μg Log in to see 2 to 3 Days
$336.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$809.60
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,182.67
Details
Yeast REACT_Escherichia coli His tag   1 mg Log in to see 56 to 66 Days
$3,263.33
Details
Yeast REACT_Pseudomonas aeruginosa His tag   1 mg Log in to see 56 to 66 Days
$3,265.17
Details
Yeast Haemophilus influenzae His tag   1 mg Log in to see 56 to 66 Days
$3,281.67
Details

GSR Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus) ,
,

Top referenced Glutathione Reductase Proteins

  1. Human Glutathione Reductase Protein expressed in Escherichia coli (E. coli) - ABIN667622 : Karplus, Schulz: Refined structure of glutathione reductase at 1.54 A resolution. in Journal of molecular biology 1987 (PubMed)
    Show all 2 references for ABIN667622

More Proteins for Glutathione Reductase (GSR) Interaction Partners

Fruit Fly (Drosophila melanogaster) Glutathione Reductase (GSR) interaction partners

  1. Molecular orbital calculations suggested that the C-terminal hexapeptide Pro-Ala-Ser (show SIGLEC1 Proteins)-Cys-Cys (show DNAJC5 Proteins)-Ser (show SIGLEC1 Proteins)-OH functions as a redox center that alleviates the necessity for selenium in Dm-TrxR.

  2. analysis of the mechanism of high Mr thioredoxin reductase from Drosophila melanogaster

  3. changing of His106 to asparagine, glutamine, and phenylalanine in various C-terminal mutants of Drosophila melanogaster thioredoxin reductase drops catalytic activity without change in pH profile

  4. X-ray crystal structure of thioredoxin reductase at 2.4 A resolution; demonstrated that tetrapeptides equivalent to the oxidized C-terminal active sites of both mouse mitochondrial TR (mTR3 (show EXOSC6 Proteins)) and DmTR are substrates for the truncated forms of both enzymes

  5. redox potentials provide direct evidence for proposed catalytic mechanism of DmTrxR, & cast new light on essential role of DmTrx system in cycling GSSG/GSH & maintaining intracellular redox homeostasis in D. melanogaster without glutathione reductase.

  6. rates of steps in both the reductive and the oxidative half-reactions are markedly diminished in H464'Q thioredoxin reductase as compared to those of wild-type enzyme, indicating that His-464' is involved in both half-reactions

  7. the role of Glu (show SLC2A1 Proteins)-469' in catalysis by DmTrxR

Arabidopsis thaliana Glutathione Reductase (GSR) interaction partners

  1. Data indicate that glutathione reductase 2 (GR2) protects photosystem II (PSII) from excess light and maintains the function of acceptor side of PSII.

  2. Plastid-localized glutathione reductase-2-regulated glutathione redox status is essential for Arabidopsis root apical meristem maintenance.

Human Glutathione Reductase (GSR) interaction partners

  1. Plasma glutathione reductase (GR) activity was correlated with erythrocyte GR activity and the erythrocyte reduced glutathione/glutathione disulfide ratio. A decrease in plasma GR activity was associated with an increase in mortality in septic shock.

  2. Glutathione reductase reduces mitochondrial protein (show COX6B2 Proteins) mitoNEET (show CISD1 Proteins) [2Fe-2S] clusters.

  3. The recurrence of benign tumors of mammary gland occurred predominantly in women-carriers of mutant alleles with polymorphism rs8190924 of gene GSR and AA rs3763511of gene DKK4 (show DKK4 Proteins).

  4. GSR was the most significant single SNP association with systemic lupus erythematosus in African Americans.

  5. 1,25 (OH) vitamin D significantly upregulated expression of GCLC (show GCLC Proteins) and GR and lowered secretion of IL-8 (show IL8 Proteins) and MCP-1 (show CCL2 Proteins) in high-glucose exposed U937 monocytes.

  6. The results demonstrate for the first time that glutathione reductase gene polymorphisms are significantly associated with bone mineral density.

  7. Up-regulation of CAT and GR activity resulted in an increase in total antioxidant activity in A549 after exposure to B (show TDO2 Proteins)(a)P.

  8. Human eye lenses were dissected into discrete regions that were formed at different stages of life and assayed for activity of lactate dehydrogenase (LDH) and a particularly stable enzyme, glutathione reductase (GR).

  9. novel glutathione reductase alternative splice variants

  10. Data show that decreased activities of GPX1 (show GPX1 Proteins), increased activities of GR and CuZnSOD (show SOD1 Proteins) in women with depressive disorder.

Mouse (Murine) Glutathione Reductase (GSR) interaction partners

  1. Data show that reducing RGS2 (show RGS2 Proteins) expression by antisense treatment prevented the increase in GLO1 (show GLO1 Proteins) and GSR1 mRNA and protein expression.

  2. Local overexpression in the mouse brain resulted in increased anxiety-like behaviour; Gsr is involved in oxidative stress metabolism, linking this pathway with anxiety-related behaviour

Cow (Bovine) Glutathione Reductase (GSR) interaction partners

  1. Liver biopsy is a valuable tool for detecting oxidative stress and for diagnosing hepatic dysfunction in cattle from glutathione and glutathione reductase levels.

Glutathione Reductase (GSR) Protein Profile

Protein Summary

This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

Gene names and symbols associated with Glutathione Reductase Proteins (GSR)

  • glutathione reductase, gro-2 (GR)
  • glutathione reductase (gor)
  • GR; GRase (gor)
  • glutathione reductase (GR)
  • glutathione reductase (GSR)
  • glutathione reductase (PtrcGR1)
  • glutathione reductase (GSR1)
  • glutathione reductase (Gsr_2)
  • glutathione reductase (GSHR1)
  • glutathione reductase (gsr)
  • glutathione reductase (LbGR)
  • glutathione reductase (pgr1)
  • glutathione reductase (GSHR2)
  • Glutathione reductase (GR) (GRase) (GLR2)
  • glutathione reductase (Bcen_2392)
  • glutathione reductase (RPE_1989)
  • glutathione reductase (HCAG_02219)
  • glutathione reductase (SJAG_01162)
  • Thioredoxin reductase-1 (Trxr-1)
  • glutathione reductase (PF14_0192)
  • glutathione reductase (PtrcGR2)
  • glutathione reductase (Gsr)
  • glutathione reductase1 (gsr1)
  • gutter shaped root (Gusr)
  • 2151 protein
  • AI325518 protein
  • anon-WO03040301.185 protein
  • anon-WO03040301.187 protein
  • ATGR2 protein
  • CG2151 protein
  • D8Ertd238e protein
  • DDBDRAFT_0168952 protein
  • DDBDRAFT_0231410 protein
  • DDB_0168952 protein
  • DDB_0231410 protein
  • Dm-TrxR protein
  • Dmel\\CG2151 protein
  • DmTR protein
  • DmTrx protein
  • DmTrxR protein
  • dmtrxr-1 protein
  • DTR protein
  • dTrxR protein
  • EMB2360 protein
  • glutathione reductase protein
  • gor1 protein
  • gr protein
  • Gr-1 protein
  • Gr1 protein
  • GSR protein
  • l(1)G0154 protein
  • l(1)G0379 protein
  • l(1)G0477 protein
  • l(1)G0481 protein
  • Trx protein
  • TrxR protein
  • trxr-1 protein
  • Trxr1 protein

Protein level used designations for Glutathione Reductase Proteins (GSR)

glutathione reductase, gro-2 , glutathione reductase , glutathione reductase, mitochondrial , glutathione-disulfide reductase , Glutathione reductase (GR) (GRase) , CG2151-PA , CG2151-PB , CG2151-PC , Trxr-1-PA , Trxr-1-PB , Trxr-1-PC , disulfide reductase , thioredoxin reductase , thioredoxin reductase-1 , GR , GRase , glutathione reductase 1 , SOG0187 , csu111 , csuh111 , gsy308(gsr) , mGR , siAJ006055 , siAJ006055_ov , siaj006055(8) , siaj006055a , umc368

GENE ID SPECIES
7447802 Thalassiosira pseudonana CCMP1335
1052725 Bradyrhizobium diazoefficiens USDA 110
3429587 Haemophilus influenzae 86-028NP
547793 Glycine max
464099 Pan troglodytes
7462504 Populus trichocarpa
5000428 Ostreococcus lucimarinus CCE9901
7200844 Phaeodactylum tricornutum CCAP 1055/1
5722016 Chlamydomonas reinhardtii
8618618 Dictyostelium discoideum AX4
3092896 Burkholderia pseudomallei K96243
6074272 Laccaria bicolor S238N-H82
2540156 Schizosaccharomyces pombe 972h-
5720329 Chlamydomonas reinhardtii
4851989 Scheffersomyces stipitis CBS 6054
4092978 Burkholderia cenocepacia AU 1054
4359499 Rhodopseudomonas palustris BisA53
5448670 Ajellomyces capsulatus NAm1
7047421 Schizosaccharomyces japonicus yFS275
31760 Drosophila melanogaster
811773 Plasmodium falciparum 3D7
7496065 Populus trichocarpa
824631 Arabidopsis thaliana
2936 Homo sapiens
14782 Mus musculus
116686 Rattus norvegicus
396625 Sus scrofa
506406 Bos taurus
100718789 Cavia porcellus
475596 Canis lupus familiaris
771783 Gallus gallus
100393824 Callithrix jacchus
541986 Zea mays
109408 Mus musculus
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