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Glutathione S-Transferase alpha 1 Proteins (GSTA1)

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. Additionally we are shipping Glutathione S-Transferase alpha 1 Antibodies (114) and Glutathione S-Transferase alpha 1 Kits (42) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GSTA1 2938 P08263
GSTA1 24422 P00502
GSTA1 14857 P13745
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Top Glutathione S-Transferase alpha 1 Proteins at antibodies-online.com

Showing 10 out of 32 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human Un-conjugated Figure annotation denotes ug of protein loaded and % gel used. 100 μg Log in to see 7 to 9 Days
$322.14
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 2 to 3 Days
$357.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 7 to 8 Days
$286.00
Details
HOST_Escherichia coli (E. coli) Rat His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$528.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$668.80
Details

GSTA1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Rat (Rattus) ,
,
Mouse (Murine)

Top referenced Glutathione S-Transferase alpha 1 Proteins

  1. Human GSTA1 Protein expressed in Escherichia coli (E. coli) - ABIN666922 : Hou, Honaker, Shireman, Balogh, Roberts, Ng, Nath, Atkins: Functional promiscuity correlates with conformational heterogeneity in A-class glutathione S-transferases. in The Journal of biological chemistry 2007 (PubMed)
    Show all 2 references for ABIN666922

More Proteins for Glutathione S-Transferase alpha 1 (GSTA1) Interaction Partners

Human Glutathione S-Transferase alpha 1 (GSTA1) interaction partners

  1. The frequency of GSTA1, GSTM1 (show GSTM1 Proteins) and GSTP1 (show GSTP1 Proteins) genotypes was not significantly different between progressive myoclonus epilepsy patients and controls

  2. GSTA1 polymorphism is associated with different pregnancy-related conditions

  3. this is the first population pharmacokinetic study to suggest that GSTA1 polymorphisms in adults are associated with busulfan pharmacokinetics

  4. GST genotyping before hematopoietic stem cell transplantation may allow better prediction of busulfan pharmacokinetics and drug toxicity, and thereby improve outcome after busulfan and cyclophosphamide conditioning

  5. the differences of PK in BU among different ethnic groups existed because of the different distribution frequencies of GST gene polymorphism in Chinese patients and Caucasian patients.

  6. Data show that the distribution of the glutathione S-transferases alleles GSTA1*A/*B and GSTP1 (show GSTP1 Proteins)*A, *B, and *C in the Polish population correspond to the results of studies in Caucasians.

  7. Patients with a GSTA1*A heterozygous variant had a lower exposure to 4-hydroxycyclophosphamide (4OHCTX) during cyclophosphamide treatment of lupus nephritis compared to wild-type patients.

  8. Our data indicated that GSTA1 expression may be a target molecule in early diagnosis and treatment of lung cancer

  9. Data suggest that cytochrome P450 3A4 (show CYP3A4 Proteins)- and glutathione S-transferase A1-transfected -hepatoma cell line C3A (show C3 Proteins) may become a cell material in the biochemical artificial liver system.

  10. The study found that GSTA1 polymorphism was associated with increased risk of Balkan endemic nephropathy.

Pig (Porcine) Glutathione S-Transferase alpha 1 (GSTA1) interaction partners

  1. cloning and characteristics of GSTA1-1

Mouse (Murine) Glutathione S-Transferase alpha 1 (GSTA1) interaction partners

  1. results suggest that GSTA1 can be detected at low concentrations during the early stages of acute hepatic injury and that GSTA1 is a more sensitive and more accurate indicator than ALT

  2. Report increased GSTA1 in airways of asthmatic mice.

  3. mitochondrial Gsta1 is induced under oxidative stress

  4. Exceptional activity of murine glutathione transferase A1-1 against (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene-induced DNA damage in stably transfected cells

  5. This is the first demonstration that heavy metals (mercury, lead and copper) regulate the expression of Gst ya gene through a transcriptional mechanism.

  6. Analysis of the expressed luciferase activity indicated that MMA activated the promoter 2.6-fold. MMA (from 1 to 30 mM) dose-dependently increased the promoter activity, which reached a plateau between 6 and 12 hrs.

  7. Essential roles of ERKs and p38K in up-regulation of GST A1 expression by Maotai content in human hepatoma cell line Hep3B.It is widely accepted that the consumption of alcohol may lead to hepatic injuries such as hepatic fibrosis and cirrhosis.

Glutathione S-Transferase alpha 1 (GSTA1) Protein Profile

Protein Summary

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.

Gene names and symbols associated with GSTA1

  • glutathione S-transferase alpha 5 (GSTA5)
  • glutathione S-transferase alpha 1 (gsta1)
  • glutathione S-transferase alpha 1 (GSTA1)
  • glutathione S-transferase alpha 1 (Gsta1)
  • glutathione S-transferase alpha 2 (Gsta2)
  • glutathione S-transferase alpha 3 (GSTA3)
  • glutathione S-transferase mu 2 (muscle) (GSTM2)
  • glutathione S-transferase, alpha 1 (Ya) (Gsta1)
  • Protein GST-2 (gst-2)
  • GST protein
  • GST2 protein
  • Gst2-1 protein
  • Gsta1 protein
  • GSTA1-1 protein
  • GSTA3 protein
  • GTH1 protein
  • OTTMUSG00000031890 protein

Protein level used designations for GSTA1

glutathione S-transferase alpha 1 , glutathione S-transferase A1 , GST HA subunit 1 , GST class-alpha member 1 , GST, class alpha, 1 , GST-epsilon , S-(hydroxyalkyl)glutathione lyase A1 , glutathione S-alkyltransferase A1 , glutathione S-aryltransferase A1 , glutathione S-transferase 2 , glutathione S-transferase Ha subunit 1 , GST class-alpha , glutathione S-transferase alpha M14 , GST 1-1 , GST 1a-1a , GST A1-1 , GST B , GST Ya1 , Glutathione-S-transferase alpha type (Yc?) , glutathione S-transferase A2 , glutathione S-transferase Ya subunit , glutathione S-transferase Ya-1 , glutathione S-transferase alpha-1 , glutathione-S-transferase, alpha type2 , ligandin , glutathione S-transferase alpha 3 , GST class-mu , GST-CL2 , GSTM1-1 , glutathione S-transferases CL2 , glutathione S-transferase Ya , glutathione S-transferase Ya1

GENE ID SPECIES
741887 Pan troglodytes
100036921 Xenopus laevis
100127839 Xenopus (Silurana) tropicalis
2938 Homo sapiens
100713029 Cavia porcellus
397682 Sus scrofa
100141301 Ovis aries
24422 Rattus norvegicus
777644 Bos taurus
414896 Gallus gallus
395976 Gallus gallus
14857 Mus musculus
177884 Caenorhabditis elegans
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