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Glutathione S-Transferase alpha 2 Proteins (GSTa2)

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. Additionally we are shipping Glutathione S-Transferase alpha 2 Antibodies (55) and Glutathione S-Transferase alpha 2 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GSTa2 24422 P00502
GSTa2 2939 P09210
GSTa2 111484  
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Top Glutathione S-Transferase alpha 2 Proteins at antibodies-online.com

Showing 9 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$704.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,552.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,553.83
Details
Yeast Human Un-conjugated   100 μg Log in to see 9 to 14 Days
$369.79
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$889.07
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

GSTa2 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human , , ,
,
Mouse (Murine)

More Proteins for Glutathione S-Transferase alpha 2 (GSTa2) Interaction Partners

Human Glutathione S-Transferase alpha 2 (GSTa2) interaction partners

  1. the GSTA2 S112T polymorphism is predictive of transplant outcome in patients receiving busulfan in the preparative regimen, at least in association with cyclophosphamide.

  2. Data indicate that steroidogenic factor 1 (SF-1 (show NR5A1 Proteins)) and glutathione S-transferase A (GSTA) family genes (hGSTA1-hGSTA4) are involved in steroidogenesis.

  3. By direct resequencing of the 5'-flanking region, all the exons, and their flanking introns for 107 patients, 29 and 27 variants were identified in GSTA1 (show GSTA1 Proteins) and GSTA2, respectively.

  4. Single nucleotide polymorphism in GSTA2 is associated with low-stage non-small cell lung cancer.

  5. Even with typical substrates, the astonishing concentration of glutathione transferase present in hepatocytes, causes an unusual "inverted" kinetics whereby the classical trends of v versus E and v versus S are reversed

  6. it is unlikely that glutathione S-transferases GSTA2, GSTM2 (show GSTM2 Proteins), GSTO1 (show GSTO1 Proteins), GSTO2 (show GSTO2 Proteins), and GSTZ1 (show GSTZ1 Proteins) participate in breast cancer susceptibility.

  7. studied the five known allelic variants of human glutathione transferase A2-2 (GST A2-2) (EC 2.5.1.18), abundantly expressed in liver and efficiently catalyzing the bioactivation of azathioprine to release 6-mercaptopurine

  8. The 3D structures of human GSTs A2-2 and A3-3 in complex with Delta(4)-androstene-3-17-dione, were solved.

  9. Polymorphism identified in the proximal promoter of GSTA2 correlate with its expression in the liver and is expected to be of significance for individual risk of cancer or individual response to chemotherapeutic agents.

  10. no association was observed between individual GSTA2 polymorphisms and haplotypes and individual susceptibility to breast cancer.

Mouse (Murine) Glutathione S-Transferase alpha 2 (GSTa2) interaction partners

  1. Data suggest that basal expression of Gsta in kidney is greater in females than in males; estradiol and triiodothyronine act together in proximal tubule cells to regulate Gsta expression.

Glutathione S-Transferase alpha 2 (GSTa2) Protein Profile

Protein Summary

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.

Gene names and symbols associated with GSTa2

  • glutathione S-transferase alpha 2 (GSTA2)
  • glutathione S-transferase alpha 2 (Gsta2)
  • glutathione S-transferase alpha 5 (Gsta5)
  • glutathione S-transferase cluster (Gsta)
  • glutathione S-transferase, alpha 2 (Yc2) (Gsta2)
  • Gst-2 protein
  • GST2 protein
  • Gst2-2 protein
  • GSTA1 protein
  • Gsta2 protein
  • GSTA2-2 protein
  • Gstc-2 protein
  • Gstc2 protein
  • GSTs protein
  • GTA2 protein
  • GTH2 protein

Protein level used designations for GSTa2

glutathione S-transferase A2 , glutathione S-transferase alpha class A2 , GST 1-1 , GST 1a-1a , GST A1-1 , GST B , GST Ya1 , Glutathione-S-transferase alpha type (Yc?) , glutathione S-transferase Ya subunit , glutathione S-transferase Ya-1 , glutathione S-transferase alpha-1 , glutathione-S-transferase, alpha type2 , ligandin , GST HA subunit 2 , GST class-alpha member 2 , GST-gamma , S-(hydroxyalkyl)glutathione lyase A2 , glutathione S-alkyltransferase A2 , glutathione S-aralkyltransferase A2 , glutathione S-aryltransferase A2 , liver GST2 , GST class-alpha member 1 , glutathione S-transferase A1 , glutathione S-transferase alpha 1 , glutathione S-transferase alpha-2 , GHS transferase , GST 1b-1b , GST A2-2 , GST Ya2 , glutathione S-transferase Ya-2 , glutathione transferase YA subunit , glutathione S-transferase GT41A

GENE ID SPECIES
462769 Pan troglodytes
100379161 Meleagris gallopavo
24422 Rattus norvegicus
2939 Homo sapiens
281805 Bos taurus
494499 Rattus norvegicus
111484 Mus musculus
14858 Mus musculus
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