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anti-Glutathione S-Transferase alpha 4 (GSTA4) Antibodies

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. Additionally we are shipping Glutathione S-Transferase alpha 4 Kits (19) and Glutathione S-Transferase alpha 4 Proteins (16) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GSTA4 300850 P14942
GSTA4 2941 O15217
GSTA4 14860 P24472
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Top anti-Glutathione S-Transferase alpha 4 Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-GSTA4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (32.16 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: 293T 12% SDS PAGE GST A4 antibody antibody diluted at 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using GSTA4, antibody at 1:100 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of GSTA4 Antibody (N-term) (ABIN652919) in HepG2 cell line lysates (35 µg/lane). GSTA4 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with GSTA4 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GSTA4 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-GSTA4. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GSTA4 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-GSTA4. Flow cytometric Analysis of Hela cells, using anti-GSTA4 antibody (ABIN2453091), (Red), compared to a nonspecific negative control antibody (TA50011), (Blue). 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Mouse Un-conjugated FACS, WB 100 μL Log in to see 8 to 10 Days
$529.83
Details

GSTA4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


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Top referenced anti-Glutathione S-Transferase alpha 4 Antibodies

  1. Human Polyclonal GSTA4 Primary Antibody for ELISA, WB - ABIN561161 : Grimsrud, Picklo, Griffin, Bernlohr: Carbonylation of adipose proteins in obesity and insulin resistance: identification of adipocyte fatty acid-binding protein as a cellular target of 4-hydroxynonenal. in Molecular & cellular proteomics : MCP 2007 (PubMed)
    Show all 2 references for ABIN561161

  2. Chicken Polyclonal GSTA4 Primary Antibody for WB - ABIN2783418 : White, Li, Nurgalieva, El-Serag: Genetic variants of glutathione S-transferase as possible risk factors for hepatocellular carcinoma: a HuGE systematic review and meta-analysis. in American journal of epidemiology 2008 (PubMed)

More Antibodies against Glutathione S-Transferase alpha 4 Interaction Partners

Human Glutathione S-Transferase alpha 4 (GSTA4) interaction partners

  1. Decreased gene expression of GSTA4 is associated with drug resistance in cervical cancer.

  2. Data indicate that steroidogenic factor 1 (SF-1 (show NR5A1 Antibodies)) and glutathione S-transferase A (GSTA (show GSTa2 Antibodies)) family genes (hGSTA1-hGSTA4) are involved in steroidogenesis.

  3. GSTA4 down-regulation and the concomitant increase in 4-hydroxynonenal adducts in muscle are indicative of susceptibility to infection in individuals with severe thermal injuries.

  4. Data show that mandatory overexpression of hGSTA4 by transient transfection in KYSE30 cells and attenuation of HNE (show ELANE Antibodies)-induced EGFR (show EGFR Antibodies) phosphorylation.

  5. analysis of four novel mutations that change the function of leukotriene C(4) synthase (show LTC4S Antibodies) and are associated with increased risk of venous thromboembolism and ischemic stroke

  6. Gsta4/GSTA4 is a novel susceptibility gene for NMSC that affects risk in both mice and humans.

  7. Results indicate that downregulation of GSTA4 in adipose tissue leads to increased protein carbonylation, ROS (show ROS1 Antibodies) production, and mitochondrial dysfunction and may contribute to the development of insulin (show INS Antibodies) resistance and type 2 diabetes.

  8. GSTA4-4 exploits the hydroxyl group of either 4R- or 4S-hydroxynonenal (HNE (show ELANE Antibodies)), while specifically binding HNE (show ELANE Antibodies) and glutathione (GSH) to maintain high catalytic efficiency linked with stereoselective product formation for both enantiomeric substrates.

  9. null mice had a significantly lower survival time than wild-type controls when chronically treated with relatively low doses of paraquat, a finding consistent with a role of glutathione transferase A4-4 in the defense against oxidative stress

  10. we observed a single nucleotide polymorphism (SNP) G351A leading to the silent mutation Gln117Gln.No significant difference was observed in the distribution of this GSTA4 polymorphism between Parkinson disease individuals and healthy controls

Mouse (Murine) Glutathione S-Transferase alpha 4 (GSTA4) interaction partners

  1. Data define a role for GSTA4-4 in buffering hepatic oxidative stress associated with chronic alcohol consumption and that this GST isoform plays an important role in protecting against carbonylation of mitochondrial proteins.

  2. although loss of GSTA4-4 led to enhanced susceptibility of cardiac mitochondria to radiation-induced loss of morphology, cardiac function was preserved in Gsta4-null mice

  3. These results indicate that 4-HNE (show ELANE Antibodies) significantly contributes to the mechanisms of tubule injury and fibrosis and that these effects can be inhibited by the enhanced expression of GSTA4-4.

  4. In the absence of GSTA4-4 to modulate both physiological and pathological 4-hydroxynonenal (HNE (show ELANE Antibodies)) levels, the adaptive NRF (show NKRF Antibodies)-E2-related (Nrf)2 (show NFE2L2 Antibodies) factor pathway may be primed to contribute to a preconditioned cardiac phenotype in the Gsta4-null mouse.

  5. The naturally occurring variation in Gsta4 expression in rats affects neurodegeneration after TBI. Further studies are needed to explore if genetic variability in Gsta4 can be associated to outcome also in human TBI.

  6. 2-APB (show RNPEP Antibodies) treatment restrained nasal lavage fluid LTC4, ECP (show ECP Antibodies), ovalbumin (show OVA Antibodies)-specific IgE, and IL-4 (show IL4 Antibodies) and their corresponding mRNAs in the previously mentioned tissues of treated mice in comparison with those of control ones.

  7. Gsta4/GSTA4 is a novel susceptibility gene for NMSC that affects risk in both mice and humans.

  8. Results indicate that downregulation of GSTA4 in adipose tissue leads to increased protein carbonylation, ROS (show ROS1 Antibodies) production, and mitochondrial dysfunction and may contribute to the development of insulin (show INS Antibodies) resistance and type 2 diabetes.

  9. mGsta4-null mice, in which 4-HNE (show ELANE Antibodies) detoxification is impaired, have an extended life span.

  10. in regenerating hepatocytes, several GST isoforms are induced and that cytokines TNFalpha (show TNF Antibodies) and IL-6 (show IL6 Antibodies) and survival factor EGF (show EGF Antibodies) positively regulate mGSTA4 via survival signaling pathways.

Glutathione S-Transferase alpha 4 (GSTA4) Antigen Profile

Protein Summary

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis.

Gene names and symbols associated with GSTA4

  • glutathione S-transferase alpha 4 (GSTA4) antibody
  • glutathione S-transferase alpha 4 (gsta4) antibody
  • glutathione S-transferase alpha 4 (Gsta4) antibody
  • glutathione S-transferase alpha 4 (LOC100341622) antibody
  • glutathione S-transferase mu 2 (Gstm2) antibody
  • glutathione S-transferase, alpha 3 (GSTA3) antibody
  • glutathione S-transferase, alpha 4 (Gsta4) antibody
  • GST5.7 antibody
  • GSTA4 antibody
  • GSTA4-4 antibody
  • GTA4 antibody
  • mGsta4 antibody
  • tGSTA4 antibody

Protein level used designations for GSTA4

glutathione S-transferase A4 , glutathione S-transferase alpha class A4 , GST 8-8 , GST A4-4 , GST K , GST Yk , glutathione S-transferase Yk , glutathione S-transferase alpha-4 , glutathione transferase , GST class-alpha member 4 , S-(hydroxyalkyl)glutathione lyase A4 , glutathione S-alkyltransferase A4 , glutathione S-aralkyltransferase A4 , glutathione S-aryltransferase A4 , glutathione S-transferase A4-4 , glutathione transferase A4-4 , GST 4-4 , GST Yb2 , GSTM2-2 , Glutathione-S-transferase mu type 2 (Yb2) , Glutathione-S-transferase, mu type 2 (Yb2) , glutathione S-transferase M2 , glutathione S-transferase Mu 2 , glutathione S-transferase Yb-2 , glutathione S-transferase Yb2 subunit , GSTA4-4 , glutathione S-transferase 5.7

GENE ID SPECIES
462771 Pan troglodytes
549430 Xenopus (Silurana) tropicalis
734548 Xenopus laevis
100379163 Meleagris gallopavo
300850 Rattus norvegicus
2941 Homo sapiens
474939 Canis lupus familiaris
533917 Bos taurus
100152951 Sus scrofa
100341622 Oryctolagus cuniculus
24424 Rattus norvegicus
768055 Bos taurus
14860 Mus musculus
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