Glutathione S-Transferase alpha 1 Proteins (GSTA1)

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. Additionally we are shipping Glutathione S-Transferase alpha 1 Antibodies (134) and Glutathione S-Transferase alpha 1 Kits (38) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GSTA1 2938 P08263
GSTA1 24422 P00502
GSTA1 14857 P13745
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Top Glutathione S-Transferase alpha 1 Proteins at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated Figure annotation denotes ug of protein loaded and % gel used. 100 μg Log in to see 6 to 8 Days
$322.14
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 2 to 3 Days
$315.00
Details
Yeast REACT_House fly His tag   1 mg Log in to see 60 to 71 Days
$2,517.17
Details
Yeast Schizosaccharomyces pombe His tag   1 mg Log in to see 60 to 71 Days
$2,579.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 15 to 19 Days
$286.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 18 Days
$608.00
Details
HOST_Human Cells Human His tag 100 μg Log in to see 20 to 21 Days
$437.80
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details

GSTA1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Rat (Rattus) ,
,
Mouse (Murine)

More Proteins for Glutathione S-Transferase alpha 1 (GSTA1) Interaction Partners

Human Glutathione S-Transferase alpha 1 (GSTA1) interaction partners

  1. Data (including data from studies using single-molecule fluorescence imaging) suggest that, for GSTA1, there are at least two conformations of the protein, consistent with model that ligand binding promotes closure of carboxy-terminal helix over active site; study involved binding of glutathione analogs and enzyme inhibitors.

  2. Combined GSTM1 (show GSTM1 Proteins), GSTT1 (show GSTT1 Proteins), GSTA1 and GSTP1 (show GSTP1 Proteins) polymorphisms might be associated to the risk of clear cell renal cell carcinoma (show MOK Proteins).

  3. Data show that the glutathione S-transferase alpha 1(GSTA1) TT genotype was more frequent in hepatocellular carcinoma (HCC (show FAM126A Proteins)) than in non-HCC (show FAM126A Proteins) patients, suggesting that individuals carrying this genotype could be associated with 2-fold higher risk of developing HCCs (show HCCS Proteins).

  4. Nrf-2 and Gst-a were more abundant in bone morrow of chronic myeloid leukemia(CML) patients compared with that of healthy donors. In addition, Nrf-2 and Gst-a were further up-regulated in samples of patients with weak response to IM. In conclusion, our study shows that rapid clearance of 4-HNE by Nrf-2/GST may represents a novel molecular basis of IM resistance in CML.

  5. Study found an association, although not statistically significant between GSTA1 gene variants and perioperative serum alpha-GST level, an indicator for liver hepatotoxicity.

  6. common polymorphisms in GSTA1, GSTM1 (show GSTM1 Proteins) and GSTT1 (show GSTT1 Proteins) are associated with susceptibility to bladder cancer in individuals from Balkan endemic nephropathy areas of Serbia.

  7. Data show that a higher concentration of fluoride in the saliva (show RAG1AP1 Proteins) was detected in children with a higher glutathione S-transferase (GST) activity.

  8. Influence of glutathione S-transferase gene polymorphisms on busulfan pharmacokinetics and outcome of hematopoietic stem-cell transplantation in thalassemia pediatric patients.

  9. The frequency of GSTA1, GSTM1 (show GSTM1 Proteins) and GSTP1 (show GSTP1 Proteins) genotypes was not significantly different between progressive myoclonus epilepsy patients and controls

  10. GSTA1 polymorphism is associated with different pregnancy-related conditions

Pig (Porcine) Glutathione S-Transferase alpha 1 (GSTA1) interaction partners

  1. cloning and characteristics of GSTA1-1

Mouse (Murine) Glutathione S-Transferase alpha 1 (GSTA1) interaction partners

  1. GSTA1 can be detected at the early stage of low concentration ethanol exposure and that GSTA1 is more sensitive and reliable marker in ethanol-induced hepatic injury.

  2. results suggest that GSTA1 can be detected at low concentrations during the early stages of acute hepatic injury and that GSTA1 is a more sensitive and more accurate indicator than ALT

  3. Report increased GSTA1 in airways of asthmatic mice.

  4. mitochondrial Gsta1 is induced under oxidative stress

  5. Exceptional activity of murine glutathione transferase A1-1 against (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene-induced DNA damage in stably transfected cells

  6. This is the first demonstration that heavy metals (mercury, lead and copper) regulate the expression of Gst ya gene through a transcriptional mechanism.

  7. Analysis of the expressed luciferase activity indicated that MMA activated the promoter 2.6-fold. MMA (from 1 to 30 mM) dose-dependently increased the promoter activity, which reached a plateau between 6 and 12 hrs.

  8. Essential roles of ERKs and p38K in up-regulation of GST A1 expression by Maotai content in human hepatoma cell line Hep3B.It is widely accepted that the consumption of alcohol may lead to hepatic injuries such as hepatic fibrosis and cirrhosis.

Glutathione S-Transferase alpha 1 (GSTA1) Protein Profile

Protein Summary

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.

Gene names and symbols associated with GSTA1

  • glutathione S-transferase alpha 5 (GSTA5)
  • glutathione S-transferase alpha 1 (gsta1)
  • glutathione S-transferase alpha 1 (GSTA1)
  • glutathione S-transferase alpha 1 (Gsta1)
  • glutathione S-transferase alpha 2 (Gsta2)
  • glutathione S-transferase alpha 3 (GSTA3)
  • glutathione S-transferase mu 2 (muscle) (GSTM2)
  • glutathione S-transferase, alpha 1 (Ya) (Gsta1)
  • Protein GST-2 (gst-2)
  • GST protein
  • GST2 protein
  • Gst2-1 protein
  • Gsta1 protein
  • GSTA1-1 protein
  • GSTA3 protein
  • GTH1 protein
  • OTTMUSG00000031890 protein

Protein level used designations for GSTA1

glutathione S-transferase alpha 1 , glutathione S-transferase A1 , GST HA subunit 1 , GST class-alpha member 1 , GST, class alpha, 1 , GST-epsilon , S-(hydroxyalkyl)glutathione lyase A1 , glutathione S-alkyltransferase A1 , glutathione S-aryltransferase A1 , glutathione S-transferase 2 , glutathione S-transferase Ha subunit 1 , GST class-alpha , glutathione S-transferase alpha M14 , GST 1-1 , GST 1a-1a , GST A1-1 , GST B , GST Ya1 , Glutathione-S-transferase alpha type (Yc?) , glutathione S-transferase A2 , glutathione S-transferase Ya subunit , glutathione S-transferase Ya-1 , glutathione S-transferase alpha-1 , glutathione-S-transferase, alpha type2 , ligandin , glutathione S-transferase alpha 3 , GST class-mu , GST-CL2 , GSTM1-1 , glutathione S-transferases CL2 , glutathione S-transferase Ya , glutathione S-transferase Ya1

GENE ID SPECIES
741887 Pan troglodytes
100036921 Xenopus laevis
100127839 Xenopus (Silurana) tropicalis
2938 Homo sapiens
100713029 Cavia porcellus
397682 Sus scrofa
100141301 Ovis aries
24422 Rattus norvegicus
777644 Bos taurus
414896 Gallus gallus
395976 Gallus gallus
14857 Mus musculus
177884 Caenorhabditis elegans
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