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Glutathione S-Transferase mu 1 Proteins (GSTM1)

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. Additionally we are shipping GSTM1 Antibodies (139) and GSTM1 Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GSTM1 2944 P09488
GSTM1 24423 P04905
GSTM1 14862 P10649
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Top GSTM1 Proteins at antibodies-online.com

Showing 10 out of 32 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated Figure annotation denotes ug of protein loaded and % gel used. 100 μg Log in to see 7 to 9 Days
$358.57
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 7 to 8 Days
$286.00
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated 100 μg Log in to see 2 to 3 Days
$315.00
Details
HOST_Escherichia coli (E. coli) Chicken His tag 100 μg Log in to see 11 to 13 Days
$616.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$728.20
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Mouse His tag   100 μg Log in to see 11 to 13 Days
$457.60
Details
HOST_Escherichia coli (E. coli) Rat His tag   100 μg Log in to see 11 to 13 Days
$492.80
Details

GSTM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Rat (Rattus) ,

Mouse (Murine)

Top referenced GSTM1 Proteins

  1. Mouse (Murine) GSTM1 Protein expressed in Escherichia coli (E. coli) - ABIN666904 : Goekkurt, Al-Batran, Hartmann, Mogck, Schuch, Kramer, Jaeger, Bokemeyer, Ehninger, Stoehlmacher et al.: Pharmacogenetic analyses of a phase III trial in metastatic gastroesophageal adenocarcinoma with fluorouracil and leucovorin plus either oxaliplatin or cisplatin: a study of the arbeitsgemeinschaft ... in Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009 (PubMed)
    Show all 2 references for ABIN666904

More Proteins for Glutathione S-Transferase mu 1 (GSTM1) Interaction Partners

Cow (Bovine) Glutathione S-Transferase mu 1 (GSTM1) interaction partners

Human Glutathione S-Transferase mu 1 (GSTM1) interaction partners

  1. Our results showed that 3 single nucleotide polymorphisms of ACE rs4340, IL-6 rs1800795, and NOS3 rs1799983 were significantly associated with the risks of mycoplasma pneumoniae pneumonia (MPP), while no differences were observed in genotype frequencies of GSTM1 and CYP1A1. The combinations of ACE/NOS3/CYP1A1 and ACE /NOS3 contribute to the genetic susceptibility of MPP in Chinese children.

  2. Our data suggest that a GSTT1 (show GSTT1 Proteins) null polymorphism might be associated with decreased risk for preeclampsia in the Chinese population, and that this risk decreases with the combination of both GSTT1 (show GSTT1 Proteins) and GSTM1 null polymorphisms.

  3. GSTM1 null, GSTT1 (show GSTT1 Proteins) null and GSTM1/T1 both or either null genotype carriers were at increased risk compared with GSTM1 active, GSTT1 (show GSTT1 Proteins) active and GSTM1/T1 both active genotypes, respectively.

  4. The association of the GSTM1 null genotype with higher micronucleus frequency observed in our study suggests that GSTM1 may be one of the major determinants of genotoxic risk in individuals exposed to pesticides and may thus be an efficient candidate for a susceptibility biomarker in human biomonitoring studies.

  5. Our results show that melanoma is apparently independent of a genetic lack of GSTM1/GSTT1 (show GSTT1 Proteins)

  6. Genotypic combinations of GSTM1/GSTT1 (show GSTT1 Proteins), rs4646903/rs1048943, and rs1801133/rs1801394 exhibited significant linkage with urothelial bladder carcinoma.

  7. Our results indicated that the GST (show SLCO6A1 Proteins)-null allele (GSTT1 (show GSTT1 Proteins)-null/GSTM1-null) is a risk factor for ESRD and carriers of this allele have high levels of MDA.

  8. study did not find a significant association between GSTM1 genotype distribution and attention deficit and hyperactivity disorder

  9. This study evaluated the influence of genetic polymorphism GSTP1 (show GSTP1 Proteins) Ile105Val, GSTM1 (null/non-null) and 2 XRCC1 (show XRCC1 Proteins) polymorphisms (Arg194Trp and Arg399Gln) on the survival of ovarian carcinoma patients treated with chemotherapy. METHODS: 106 patients received treatment with a carboplatin-based or alternative chemotherapy. Polymorphisms were genotyped by pyrosequencing.

  10. Study shows the frequency of the GSTM1 present genotype in atherosclerosis group was 1.2 times higher than in the control group and even more frequent with smoking habits with statistically significant difference.

Mouse (Murine) Glutathione S-Transferase mu 1 (GSTM1) interaction partners

  1. Six proteins were regulated at both basal and inducible levels exhibiting the largest dynamic range of Nrf2 (show NFE2L2 Proteins) regulation: cytochrome CYP2A5, GSTM3 (show glutathione S-transferase mu 3 (brain) Proteins), GSTM1, ENTPD5 (show ENTPD5 Proteins),UDPGDH (show UGDH Proteins), and EPHX1 (show EPHX1 Proteins).

  2. mitochondrial Gstb1 is induced under oxidative stress

  3. the gene (GSTM1) encoding the detoxification enzyme glutathione S-transferase M1 is transcriptionally upregulated by Myb (show MYB Proteins)

  4. The Gstm1 gene was represented by two EST (show MAP3K8 Proteins) clones with similar levels of downregulation.

  5. We overexpressed Hoxa9 (show HOXA9 Proteins) and Meis1 (show MEIS1 Proteins) in primary hematopoietic cells. Arrays identified c-Myb (show MYB Proteins) and a c-Myb (show MYB Proteins) target (Gstm1) among the genes with the strongest response to Hoxa9 (show HOXA9 Proteins)/Meis1 (show MEIS1 Proteins).

  6. Genetic variants that cause a decremental change in expression of Gstm1 may permit an environment of exaggerated oxidative stress, leading to susceptibility to vascular remodeling and atherosclerosis

  7. The role of polymorphisms of glutathione S-transferases GSTM1, M3, P1, T1 and A1 in susceptibility to alcoholic liver disease. In addition, oxidant stress is proposed to be an important pathogenic factor in liver damage related to alcohol.

GSTM1 Protein Profile

Protein Summary

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.

Gene names and symbols associated with GSTM1

  • glutathione S-transferase M1 (GSTM1)
  • glutathione S-transferase mu 1-like (LOC615514)
  • glutathione S-transferase mu 1 (GSTM1)
  • glutathione S-transferase mu 1 (LOC100356307)
  • glutathione S-transferase mu 1 (Gstm1)
  • Glutathione S-transferase Mu 1-like (LOC100358177)
  • glutathione S-transferase mu 2 (muscle) (GSTM2)
  • glutathione S-transferase mu 4 (GSTM4)
  • glutathione S-transferase, mu 1 (Gstm1)
  • GST1 protein
  • GST4 protein
  • GSTA3 protein
  • Gstb-1 protein
  • Gstb1 protein
  • GSTM protein
  • GSTM1 protein
  • GSTM1-1 protein
  • GSTM1a-1a protein
  • GSTM1b-1b protein
  • GSTM2-2 protein
  • GSTM4 protein
  • GTH4 protein
  • GTHMUS protein
  • GTM1 protein
  • H-B protein
  • MU protein
  • MU-1 protein

Protein level used designations for GSTM1

GST class-mu 1 , GSTM1-1 , glutathione S-transferase Mu 1 , glutathione S-transferase mu 1 , glutathione S-transferase M1 , GST HB subunit 4 , HB subunit 4 , S-(hydroxyalkyl)glutathione lyase , glutathione S-alkyltransferase , glutathione S-aralkyltransferase , glutathione S-aryltransferase , glutathione S-transferase M4 , glutathione S-transferase mu 4 , GST 3-3 , GST Yb1 , glutathione S-transferase Yb-1 subunit , glutathione-S-transferase mu type 1 (Yb1) , glutathione-S-transferase, mu type 1 (Yb1) , GST class-mu 2 , GST, muscle , S-(hydroxyalkyl)glutathione lyase M2 , glutathione S-alkyltransferase M2 , glutathione S-aralkyltransferase M2 , glutathione S-aryltransferase M2 , glutathione S-transferase 4 , glutathione S-transferase M2 (muscle) , glutathione S-transferase Mu 2 , GST 1-1 , glutathione S-transferase GT8.7 , glutathione-S-transferase, mu 1 , pmGT10

GENE ID SPECIES
327709 Bos taurus
615514 Bos taurus
700178 Macaca mulatta
745723 Pan troglodytes
100356307 Oryctolagus cuniculus
2944 Homo sapiens
783879 Bos taurus
24423 Rattus norvegicus
100731426 Cavia porcellus
100358177 Oryctolagus cuniculus
2946 Homo sapiens
479912 Canis lupus familiaris
14862 Mus musculus
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