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Glyceraldehyde-3-Phosphate Dehydrogenase, Spermatogenic Proteins (GAPDHS)

GAPDHS encodes a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism. Additionally we are shipping Glyceraldehyde-3-Phosphate Dehydrogenase, Spermatogenic Antibodies (52) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GAPDHS 26330 O14556
GAPDHS 14447 Q64467
GAPDHS 66020 Q9ESV6
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Top Glyceraldehyde-3-Phosphate Dehydrogenase, Spermatogenic Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag   10 μg Log in to see 9 Days
$405.71
Details
Yeast Mesocricetus auratus His tag   1 mg Log in to see 56 to 66 Days
$2,174.33
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,905.83
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,091.00
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$3,135.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,206.50
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

GAPDHS Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced Glyceraldehyde-3-Phosphate Dehydrogenase, Spermatogenic Proteins

  1. Human GAPDHS Protein expressed in Wheat germ - ABIN1354793 : Margaryan, Dorosh, Capkova, Manaskova-Postlerova, Philimonenko, Hozak, Peknicova: Characterization and possible function of glyceraldehyde-3-phosphate dehydrogenase-spermatogenic protein GAPDHS in mammalian sperm. in Reproductive biology and endocrinology : RB&E 2015 (PubMed)

More Proteins for Glyceraldehyde-3-Phosphate Dehydrogenase, Spermatogenic (GAPDHS) Interaction Partners

Human Glyceraldehyde-3-Phosphate Dehydrogenase, Spermatogenic (GAPDHS) interaction partners

  1. Structural basis for the NAD binding cooperativity and catalytic characteristics of sperm-specific glyceraldehyde-3-phosphate dehydrogenase (show GAPDH Proteins)

  2. GAPDS protein was expressed in both Sertoli cells and elongated sperms. The expression of GAPDS gradually increased with age in the epididymis.

  3. Data indicate that the positive expression of studied genes fertilization rate for GAPDHS positive subset was 66%, ACR (show ACR Proteins) - 71%, SPATA22 - 68%, MND1 (show MND1 Proteins) - 70%, pregnancy rates were 8%, 6%, 18% and 36% respectively.

  4. the expression of GAPDS in melanoma cells may facilitate glycolysis and prevent the induction of apoptosis.

  5. The chaperonin (show HSPD1 Proteins) TRiC (show MARVELD2 Proteins) was shown to assist an ATP-dependent refolding of recombinant forms of GAPDS.

  6. Structure and kinetic characterization of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase (show GAPDH Proteins), GAPDS.

  7. Human his-GAPDHS expressed in baculovirus-infected insect cells is homotetrameric.

  8. Data suggest that high stability of the sperm-specific GAPDS is of importance for the efficiency of fertilization.

  9. We have concluded that a simple nuclear localization of GAPDH (show GAPDH Proteins) does not induce apoptosis, and that MPP+-induced apoptosis is not caused by nuclear translocation of GAPDH (show GAPDH Proteins).

  10. Comparative study of the amino acid sequences of mammalian GAPDs revealed conservative cysteine residues (C21, C94, and C150) that are specific for the sperm isoenzyme and absent in the somatic isoenzyme.

Mouse (Murine) Glyceraldehyde-3-Phosphate Dehydrogenase, Spermatogenic (GAPDHS) interaction partners

  1. TB-RBP (show TSN Proteins) is involved in the posttranscriptional regulation of Gapds gene expression during spermiogenesis.

  2. Gapds(-/-) males were infertile and had profound defects in sperm motility, exhibiting sluggish (show PRODH Proteins) movement without forward progression.

Glyceraldehyde-3-Phosphate Dehydrogenase, Spermatogenic (GAPDHS) Protein Profile

Protein Summary

This gene encodes a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility.

Gene names and symbols associated with GAPDHS

  • glyceraldehyde-3-phosphate dehydrogenase, spermatogenic (GAPDHS)
  • glyceraldehyde-3-phosphate dehydrogenase, spermatogenic (LOC100352213)
  • glyceraldehyde-3-phosphate dehydrogenase, spermatogenic (Gapdhs)
  • glyceraldehyde-3-phosphate dehydrogenase, spermatogenic (gapdhs)
  • cb350 protein
  • fb71f08 protein
  • fk58c09 protein
  • g3pdh protein
  • Gapd-s protein
  • GAPD2 protein
  • gapdh protein
  • gapdh-2 protein
  • GAPDHS protein
  • gapds protein
  • HSD-35 protein
  • wu:fb71f08 protein
  • wu:fk58c09 protein
  • zgc:76908 protein

Protein level used designations for GAPDHS

glyceraldehyde-3-phosphate dehydrogenase, spermatogenic , glyceraldehyde-3-phosphate dehydrogenase, testis-specific-like , glyceraldehyde-3-phosphate dehydrogenase, testis-specific , spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2 , spermatogenic glyceraldehyde-3-phosphate dehydrogenase , GAPDH-2 , glyceraldehyde-3-phosphate dehydrogenase type 2 , glyceraldehyde 3-phosphate dehydrogenase 2 , glyceraldehyde 3-phosphate dehydrogenase, testis-specific

GENE ID SPECIES
455951 Pan troglodytes
709485 Macaca mulatta
100352213 Oryctolagus cuniculus
100389039 Callithrix jacchus
100605071 Nomascus leucogenys
26330 Homo sapiens
14447 Mus musculus
66020 Rattus norvegicus
476483 Canis lupus familiaris
406367 Danio rerio
532231 Bos taurus
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