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a putative membrane glycerophosphodiester phosphodiesterase\; may mediate lipid metabolism and G protein signaling [RGD, Feb 2006].. Additionally we are shipping GDE1 Antibodies (54) and GDE1 Proteins (7) and many more products for this protein.
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The expression levels of two target genes, Myb (show MYB ELISA Kits) and VEGFR2 (show KDR ELISA Kits), were affected significantly by miR-16, while glucose administration inhibited miR-16 expression and enhanced tumor cell proliferation and migration.
Quercetin decreases claudin-2 (show CLDN2 ELISA Kits) expression mediated by up-regulation of miR-16 expression and instability of claudin-2 (show CLDN2 ELISA Kits) mRNA in lung adenocarcinoma cells.
Our data indicate differential concentrations of plasma miR-16, miR (show MLXIP ELISA Kits)-107, miR (show MLXIP ELISA Kits)-130a and miR (show MLXIP ELISA Kits)-146a in different breast cancer subtypes, suggesting a potential role of these miRs in breast cancer biology and tumor progression.
YAP1 (show YAP1 ELISA Kits) was confirmed to be a functional target of miR (show MLXIP ELISA Kits)-15a and miR-16-1 in GAC (show GLS ELISA Kits).
miR-16 and miR (show MLXIP ELISA Kits)-26a target checkpoint kinases Wee1 (show WEE1 ELISA Kits) and Chk1 (show CHEK1 ELISA Kits) in response to p53 (show TP53 ELISA Kits) activation by genotoxic stress.
Up-regulation of miR-16 is associated with triple negative breast cancer.
This study demonistrated that miR (show MLXIP ELISA Kits)-15a and 16-1 are downregulated in CD4 (show CD4 ELISA Kits)+ T cells of multiple sclerosis relapsing patients.
miR-16 and miR (show MLXIP ELISA Kits)-21 are directly regulated by the transcription factor NF-kappaB (show NFKB1 ELISA Kits) and yet nicotine-promoted cell proliferation is mediated via EP2/4 receptors.
Results suggest an important role of miR-16 in the regulation of Wip1 phosphatase in the DNA damage response and mammary tumorigenesis.
These findings suggest that genes other than miR (show MLXIP ELISA Kits)-15a and miR-16 may explain the prognostic significance of 13q14 deletions in patients with multiple myeloma
The authors confirmed the role of Gde1 in NAFLD (show TSC2 ELISA Kits) by in vivo hepatic over-expression and shRNA knockdown studies.
findings designate GroPSer as a previously unappreciated reservoir for free serine in the nervous system and suggest that GDE1, through recycling serine from GroPSer, may impact D-serine-dependent neural signaling processes in vivo
regulation by by stimulation of G protein-coupled receptors
a multistep pathway for the production of anandamide in the nervous system by the sequential actions of Abh4 (show ABHD4 ELISA Kits) and GDE1.
a putative membrane glycerophosphodiester phosphodiesterase\; may mediate lipid metabolism and G protein signaling
RGS16-interacting membrane protein
, membrane interacting protein of RGS16
, membrane-interacting protein of RGS16