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anti-Glycine Dehydrogenase (GLDC) Antibodies

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein . Additionally we are shipping Glycine Dehydrogenase Kits (17) and Glycine Dehydrogenase Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GLDC 104174 Q91W43
GLDC 2731 P23378
GLDC 309312  
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Top anti-Glycine Dehydrogenase Antibodies at antibodies-online.com

Showing 10 out of 56 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of GLDC Antibody (N-term) in mouse liver tissue lysates (35ug/lane). GLDC (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of GLDC Antibody (N-term) (ABIN653448) in mouse liver tissue lysates (35 µg/lane). GLDC (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IF, IP, IHC (p) IP Image Immunoprecipitation of Glycine dehydrogenase protein from HepG2 whole cell extracts using 5 μg of Glycine dehydrogenase antibody [N3C2-2], Internal, Western blot analysis was performed using Glycine dehydrogenase antibody [N3C2-2], Internal, EasyBlot anti-Rabbit IgG  was used as a secondary reagent. ICC/IF Image Glycine dehydrogenase antibody [N3C2-2], Internal detects Glycine dehydrogenase protein at mitochondria by immunofluorescent analysis. Sample: HepG2 cells were fixed in ice-cold MeOH for 5 min. Green: Glycine dehydrogenase protein stained by Glycine dehydrogenase antibody [N3C2-2], Internal , diluted at 1:500. Blue: Hoechst 33342 staining. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 11 to 13 Days
$385.00
Details
Human Rabbit Un-conjugated IHC (fp), IF, WB 100 μL Log in to see 6 to 11 Days
$485.71
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Mouse Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$396.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), SimWes, WB   100 μL Log in to see 5 to 7 Days
$452.81
Details

GLDC Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Glycine Dehydrogenase Antibodies

  1. Human Polyclonal GLDC Primary Antibody for EIA, WB - ABIN952523 : Chang, Lin, Lin, Chuang, Ho, Hsu: Non-ketotic hyperglycinemia with a novel GLDC mutation in a Taiwanese child. in Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi 2008 (PubMed)

More Antibodies against Glycine Dehydrogenase Interaction Partners

Mouse (Murine) Glycine Dehydrogenase (GLDC) interaction partners

  1. These studies support a direct relationship between p53 (show TP53 Antibodies) mutations and GLDC expression in B cell lymphoma.

  2. Glycine decarboxylase deficiency causes neural tube defects and features of non-ketotic hyperglycinemia in mice through limiting supply of one-carbon units from mitochondrial folate metabolism.

  3. Results suggest that there is a direct correlation between ischemic injury and extracellular glycine concentration maintained by glycine decarboxylase and the glycine cleavage multienzyme system.

Human Glycine Dehydrogenase (GLDC) interaction partners

  1. Data indicate no mutation was found in glycine cleavage system protein-H (show GCSH Antibodies) (GCSH (show GCSH Antibodies)) and suggest that mutations in both glycine decarboxylase (GLDC) and aminomethyltransferase (AMT (show AMT Antibodies)) are the main cause of glycine encephalopathy in Malaysian population.

  2. study reports a novel mutation, c.2296G>T (p.Gly766Cys), in exon 19 of the glycine decarboxylase (GLDC) gene in a consanguineous Indian couple with a history of 4 neonatal deaths

  3. Identification of a splice acceptor site mutation and five different non-synonymous variants in GLDC were found in patients with neural tube defects.

  4. Study shows that glycine metabolism and the metabolic enzyme glycine decarboxylase (GLDC) drive tumor-initiating cells and tumorigenesis in non-small cell lung cancer.

  5. Heterozygous GLDC gene mutation in transient neonatal hyperglycinemia.

  6. Three adults with mild hyperglycinemia, infantile hypotonia, mental retardation, behavioral hyperirritability, and aggressive outbursts were screened for glycine decarboxylase mutations; two novel missense mutations were found.

  7. The mutation in this nonketotic hyperglycinemia kindred led to missplicing and reduced GLDC (glycine decarboxylase) expression.

  8. Single nucleotide substitution that abolishes the initiator methionine codon of the GLDC gene is associated with glycine encephalopathy

  9. the nonketotic hyperglycinemia is due to a novel GLDC mutation.

  10. forty different gene alterations in the GLDC gene were identified in patients with glycine encephalopathy

Glycine Dehydrogenase (GLDC) Antigen Profile

Protein Summary

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).

Gene names and symbols associated with GLDC

  • glycine dehydrogenase (gcvP) antibody
  • glycine dehydrogenase (Tb927.7.1910) antibody
  • glycine cleavage system P-protein (gcvP) antibody
  • glycine decarboxylase (Gldc) antibody
  • glycine dehydrogenase (decarboxylating) (GLDC) antibody
  • glycine dehydrogenase (decarboxylating) (Gldc) antibody
  • D030049L12Rik antibody
  • D19Wsu57e antibody
  • DDBDRAFT_0219205 antibody
  • DDBDRAFT_0231130 antibody
  • DDB_0219205 antibody
  • DDB_0231130 antibody
  • GCE antibody
  • GCSP antibody
  • HYGN1 antibody
  • PSPTO1276 antibody
  • Tb07.43M14.350 antibody

Protein level used designations for GLDC

glycine dehydrogenase , glycine cleavage system P protein , glycine dehydrogenase [decarboxylating], mitochondrial , glycine cleavage system protein P , glycine decarboxylase P-protein , glycine cleavage system protein P) , glycine decarboxylase , glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P) , glycine decarboxylase, glycine cleavage system protein P)

GENE ID SPECIES
1168636 Shewanella oneidensis MR-1
1182912 Pseudomonas syringae pv. tomato str. DC3000
3196586 Ruegeria pomeroyi DSS-3
3658401 Trypanosoma brucei brucei strain 927/4 GUTat10.1
8626028 Dictyostelium discoideum AX4
104174 Mus musculus
2731 Homo sapiens
374222 Gallus gallus
481534 Canis lupus familiaris
309312 Rattus norvegicus
Selected quality suppliers for anti-Glycine Dehydrogenase (GLDC) Antibodies
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