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anti-Glycine N-Methyltransferase (GNMT) Antibodies

The protein encoded by GNMT is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. Additionally we are shipping GNMT Proteins (17) and GNMT Kits (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GNMT 14711 Q9QXF8
GNMT 25134 P13255
GNMT 27232 Q14749
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Top anti-GNMT Antibodies at antibodies-online.com

Showing 10 out of 65 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of GNMT (arrow) using rabbit polyclonal GNMT Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GNMT gene. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded rat kidney labeled with Rabbit Anti GNMT Polyclonal Antibody, Unconjugated (ABIN739680) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse Un-conjugated FACS, WB 100 μL Log in to see 8 to 10 Days
$529.83
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Biotin ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

GNMT Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , ,


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Rat (Rattus) , ,


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More Antibodies against GNMT Interaction Partners

Mouse (Murine) Glycine N-Methyltransferase (GNMT) interaction partners

  1. GNMT is involved in the pathogenesis of experimental autoimmune encephalomyelitis and plays a crucial role in the regulation of CD4 (show CD4 Antibodies)+ T-cell functions

  2. GNMT is found in the hippocampus and regulates intracellular SAMe levels. GNMT deficiency in mice results in high SAMe levels within the hippocampus, reduced neurogenic capacity, and spatial learning and memory impairment.

  3. It may be a crucial molecule in the pathogenesis of DSS (show PMP22 Antibodies)-induced colitis.

  4. Gnmt plays important role in maintaining normal function of brain; deficiency of Gnmt causes dysfunction of important signaling pathways and results in alterations of neurotransmitter secretion as well as changes in neuropsychological behavior.

  5. Reduced expression of GNMT in mouse hepatoma cells appears to increase the activity of LKB1/RAS signaling.

  6. NK cells from GNMT(-/-) mice were spontaneously activated, expressed more TRAIL, and had strong cytotoxic activity, suggesting their contribution to the proinflammatory environment in the liver.

  7. This is the first report demonstrating that GNMT plays an important role in regulating cholesterol homeostasis via interaction with NPC2 (show NPC2 Antibodies)

  8. Higher susceptibility to aflatoxin B(1)-related hepatoma in Gnmt deficient mice.

  9. Loss of GNMT induces aberrant methylation of DNA and histones, resulting in epigenetic modulation of critical carcinogenic pathways.

  10. GNMT is a tumor suppressor gene for liver cancer, and it is associated with gender disparity in liver cancer susceptibility as shown in humans and in mouse models

Human Glycine N-Methyltransferase (GNMT) interaction partners

  1. In men of European descent, the GNMT rs10948059 and short tandem repeat polymorphism 1 were associated with prostate cancer risk.

  2. GNMT is an androgen receptor (show AR Antibodies)-targeted gene with its functional androgen response element located at +19/+33 of the first exon.

  3. The studies identify GNMT as a direct transcriptional target of the AR.

  4. DNA hypermethylation plays an important role in the repression of GNMT in hepatocellular carcinoma (HCC (show FAM126A Antibodies)), and loss of GNMT in human HCC (show FAM126A Antibodies) could promote the establishment of aberrant DNA methylation (show HELLS Antibodies) patterns at specific gene promoters

  5. single-nucleotide polymorphisms in VEGF (show VEGFA Antibodies), IL-10 (show IL10 Antibodies) and GNMT genes might have a synergistic role in the development of Prostate cancer

  6. Report SNPs that are highly associated with hepatic GNMT protein expression and the coordinate regulation of MAT1A (show MAT1A Antibodies) levels.

  7. GNMT plays important role in maintaining normal function of brain; lack of GNMT causes dysfunction of important signaling pathways and results in alterations of neurotransmitter secretion as well as changes in neuropsychological behavior.

  8. GNMT is a crucial regulator in cholesterol metabolism and in inflammation, and contributes to the pathogenesis of atherosclerosis.

  9. In conclusion, GNMT regulates hepatocellular carcinoma growth in part through interacting with DEPDC6/DEPTOR (show DEPTOR Antibodies) and modulating mTOR (show FRAP1 Antibodies)/raptor (show RPTOR Antibodies) signaling pathway

  10. This is the first report demonstrating that GNMT plays an important role in regulating cholesterol homeostasis via interaction with NPC2 (show NPC2 Antibodies)

GNMT Antigen Profile

Protein Summary

The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia).

Gene names and symbols associated with GNMT

  • glycine N-methyltransferase (CpipJ_CPIJ015956) antibody
  • glycine N-methyltransferase (Gnmt) antibody
  • glycine N-methyltransferase (GNMT) antibody

Protein level used designations for GNMT

glycine N-methyltransferase , glycine N methyl transferase , folate-binding protein , glycine methyltransferase

GENE ID SPECIES
6049618 Culex quinquefasciatus
14711 Mus musculus
25134 Rattus norvegicus
27232 Homo sapiens
474905 Canis lupus familiaris
397444 Sus scrofa
538212 Bos taurus
100009512 Oryctolagus cuniculus
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