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Glycine Receptor, alpha 2 Proteins (GLRa2)

The glycine receptor consists of two subunits, alpha and beta, and acts as a pentamer. Additionally we are shipping GLRa2 Antibodies (13) and GLRa2 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GLRa2 14527 Q61606
Rat GLRa2 GLRa2 24953 P30082
GLRa2 2742 P23416
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Top GLRa2 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Mouse GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Mouse His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

GLRa2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , ,
, ,
Human , ,
, ,

More Proteins for Glycine Receptor, alpha 2 (GLRa2) Interaction Partners

Mouse (Murine) Glycine Receptor, alpha 2 (GLRa2) interaction partners

  1. glucagon receptor (show GCGR Proteins) antagonist improves glycemia in diet-induced obese angptl4 (show ANGPTL4 Proteins) knockout mice without increasing glucagon (show GCG Proteins) levels or alpha-cell proliferation, underscoring the importance of this protein.

  2. genetic inactivation of Glra2, the gene coding the alpha2 subunit of GlyRs (show GARS Proteins), disrupts dorsal cortical progenitor homeostasis with an impaired capability of apical progenitors to generate basal progenitors.

  3. Data indicate that the exocrine pancreas in the glucagon receptor Gcgr (show GCGR Proteins)-/- mice exhibited larger nuclear size than in WT or heterozygous controls, most obviously at old ages.

  4. Simultaneous and sufficient activation of GLP1R (show GLP1R Proteins) is required to reduce GCCR (show NR3C1 Proteins) mediated blood glucose elevation following administration of a GLP1R (show GLP1R Proteins)/GCGR (show GCGR Proteins) co-agonist.

  5. Knockdown of liver glucagon receptor (show GCGR Proteins) in mice reduces blood glucose and increases blood LDL levels.

  6. Endogenous activation of Glra2 promotes neuronal migration by regulating nucleokinesis.

  7. Gcgr (show GCGR Proteins)(-/-) mice became lethargic (show CACNB4 Proteins) & cachexic & died early. Autopsy revealed numerous PNETs up to 15 mm in diameter in most well-preserved Gcgr (show GCGR Proteins)(-/-) pancreata.

  8. Data suggest that GcgR (show GCGR Proteins) activation raises hepatic expression of fibroblast growth factor 21 (FGF21 (show FGF21 Proteins)) and increases circulating levels of FGF21 (show FGF21 Proteins); GcgR (show GCGR Proteins) activation induces body weight loss and stimulates lipid metabolism.

  9. These results suggest that a circulating factor generated after disruption of hepatic Gcgr (show GCGR Proteins) signaling can increase alpha-cell proliferation independent of direct pancreatic input.

  10. GRA1 is a potent glucagon receptor (show GCGR Proteins) antagonist with strong antihyperglycemic efficacy in preclinical models and prominent effects on hepatic gene-expression related to amino acid metabolism

Human Glycine Receptor, alpha 2 (GLRa2) interaction partners

  1. investigated neural progenitor cells in respect to their glycine receptor (show GLRB Proteins) function and subunit expression using electrophysiology, calcium imaging, immunocytochemistry, and quantitative real-time PCR

  2. Enhancement of azurophil granule-phagosome fusion via glycine receptor alpha 2 subunit (GlyRalpha2)/transient receptor potential melastatin (show TRPM1 Proteins) (TRPM)2 (show CLU Proteins)/p38 MAP kinase (show MAPK14 Proteins) signaling is a novel target for enhancement of neutrophil bactericidal activity.

  3. Effects of 12 times normal atmospheric pressure of helium-oxygen gas (pressure) on ethanol-induced potentiation of GlyR function in Xenopus oocytes expressing human alpha1, alpha2 or the mutant alpha1(A52S) GlyRs were measured by voltage clamp technics

  4. The molecular basis for the differential sensitivity of GlyR alpha(1) and GlyR alpha(2) to Zn(2+) potentiation is reported.

GLRa2 Protein Profile

Protein Summary

The glycine receptor consists of two subunits, alpha and beta, and acts as a pentamer. The protein encoded by this gene is an alpha subunit and can bind strychnine. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with GLRa2

  • glycine receptor, alpha 2 (GLRA2)
  • glucagon receptor (Gcgr)
  • glycine receptor alpha 2 (glra2)
  • glycine receptor, alpha 2 (Glra2)
  • glycine receptor, alpha 2 subunit (Glra2)
  • GLR protein
  • GR protein
  • RNNEOGLY protein

Protein level used designations for GLRa2

glycine receptor, alpha 2 , glycin receptor,alpha 2 , glycine receptor subunit alpha-2 , glycine receptor subunit alpha-2-like , GL-R , glucagon receptor perhaps same as Niddm3 , glycine receptor alpha 2 subunit , glycine receptor, alpha-2 polypeptide , Glycine receptor alpha 2 subunit (glycine receptor, neonatal) , glycine receptor strychnine-binding subunit , glycine receptor, alpha 2 subunit

GENE ID SPECIES
281784 Bos taurus
465502 Pan troglodytes
491746 Canis lupus familiaris
537660 Bos taurus
772019 Gallus gallus
100403670 Callithrix jacchus
100457201 Pongo abelii
100538616 Meleagris gallopavo
14527 Mus musculus
24953 Rattus norvegicus
793646 Danio rerio
2742 Homo sapiens
24397 Rattus norvegicus
237213 Mus musculus
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