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GLRA4 encodes a protein which has a neurotransmitter-gated ion-channel ligand binding domain.
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The alpha4 subunit was localized in the inner plexiform layer (IPL (show PHLDA2 Proteins)) in brightly fluorescent puncta, which represent postsynaptically clustered glycine receptors.
Glycine receptors (GlyRs (show GARS Proteins)) of group II cells are dominated by the alpha2 subunit; GlyRs (show GARS Proteins) of ON-starburst amacrine cells appear to be dominated by the alpha4 subunit.
This gene encodes a protein which has a neurotransmitter-gated ion-channel ligand binding domain. The encoded protein is very similar to a mouse protein which is a subunit of the retinal glycine receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
glycine receptor, alpha 4
, glycine receptor subunit alpha-4
, glycine receptor, alpha 4 subunit