You are viewing an incomplete version of our website. Please click to reload the website as full version.

Glycine Receptor, beta Proteins (GLRB)

GLRB encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. Additionally we are shipping GLRB Antibodies (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GLRB 2743 P48167
Rat GLRB GLRB 25456 P20781
GLRB 14658 P48168
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top GLRB Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details

GLRB Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine) ,
,

More Proteins for Glycine Receptor, beta (GLRB) Interaction Partners

Human Glycine Receptor, beta (GLRB) interaction partners

  1. GLRA1 (show GLRA1 Proteins) and GLRB mutations are responsible for abnormal startled reactions in humans. (Review)

  2. The N-terminal region of GABRA3 (show GABRA3 Proteins) and the GlyR beta subunit (show POLG Proteins) occupies the same binding site of gephyrin (show GPHN Proteins).

  3. We report novel GLRB mutations in hyperekplexia

  4. Systematic DNA sequencing of GLRB in individuals with hyperekplexia revealed new missense mutations in GLRB, resulting in M177R, L285R and W310C substitutions.

  5. This study describes the definitive assignment of GLRB as the third major gene for hyperekplexia and impacts on the genetic stratification and biological causation of this neonatal/paediatric disorder.

  6. investigated neural progenitor cells in respect to their glycine receptor function and subunit expression using electrophysiology, calcium imaging, immunocytochemistry, and quantitative real-time PCR

  7. Distinct properties of glycine receptor beta+/alpha- interface: unambiguously characterizing heteromeric interface reconstituted in homomeric protein.

  8. This study presents a large family with Hereditary hyperekplexia (HH) as a result of homozygous mutation in GLRB.

  9. Hereditary hyperekplexia-causing mutations that modify alpha1 beta GlyR channel function are almost exclusively located in the alpha1 to the exclusion of the beta subunit (show POLG Proteins).

  10. The authors have identified a protein kinase C (PKC) phosphorylation site within the cytoplasmic domain of the beta-subunit of the GlyR (residue S403) that causes a reduction of the binding affinity between the receptor and gephyrin.

Mouse (Murine) Glycine Receptor, beta (GLRB) interaction partners

  1. A species-specific thymine-to-guanine sequence variation in the Glrb gene has been identified which gives rise to species-specific splice donor sites in the Glrb genes of mouse and bushbaby.

  2. The SdpI (show PACSIN1 Proteins)-binding site was mapped to a proline-rich sequence of 22 amino acids within the intracellular loop of GlyRbeta.

  3. These results show that insulin (show INS Proteins) has a novel regulatory action on the potency of glycine for ionotropic glycine receptors.

  4. Visual stimulation regulates maturation of retinal ganglion cell synaptic activity and connectivity primarily through glycine receptor-mediated synaptic transmission.

GLRB Protein Profile

Protein Summary

This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with Glycine Receptor, beta Proteins (GLRB)

  • glycine receptor, beta (GLRB)
  • glycine receptor, beta (glrb)
  • glycine receptor, beta (Glrb)
  • glycine receptor, beta subunit (Glrb)
  • AI853901 protein
  • glrb protein
  • Glyrb protein
  • HKPX2 protein
  • MGC145156 protein
  • spa protein
  • spastic protein

Protein level used designations for Glycine Receptor, beta Proteins (GLRB)

glycine receptor, beta , glycine receptor subunit beta , glycine receptor subunit beta-like , glycine receptor 58 kDa subunit , glycine receptor, beta subunit , glycine receptor beta , inhibitory glycine receptor

GENE ID SPECIES
100061981 Equus caballus
461569 Pan troglodytes
700368 Macaca mulatta
779708 Xenopus (Silurana) tropicalis
100172764 Pongo abelii
100392393 Callithrix jacchus
100480924 Ailuropoda melanoleuca
100548283 Meleagris gallopavo
100567921 Anolis carolinensis
100586448 Nomascus leucogenys
281198 Bos taurus
2743 Homo sapiens
25456 Rattus norvegicus
422411 Gallus gallus
475477 Canis lupus familiaris
414284 Sus scrofa
14658 Mus musculus
Selected quality suppliers for GLRB Proteins (GLRB)
Did you look for something else?