Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
GLRB encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. Additionally we are shipping GLRB Antibodies (22) and many more products for this protein.
Showing 4 out of 6 products:
GLRA1 (show GLRA1 Proteins) and GLRB mutations are responsible for abnormal startled reactions in humans. (Review)
The N-terminal region of GABRA3 (show GABRA3 Proteins) and the GlyR beta subunit (show POLG Proteins) occupies the same binding site of gephyrin (show GPHN Proteins).
We report novel GLRB mutations in hyperekplexia
Systematic DNA sequencing of GLRB in individuals with hyperekplexia revealed new missense mutations in GLRB, resulting in M177R, L285R and W310C substitutions.
This study describes the definitive assignment of GLRB as the third major gene for hyperekplexia and impacts on the genetic stratification and biological causation of this neonatal/paediatric disorder.
investigated neural progenitor cells in respect to their glycine receptor function and subunit expression using electrophysiology, calcium imaging, immunocytochemistry, and quantitative real-time PCR
Distinct properties of glycine receptor beta+/alpha- interface: unambiguously characterizing heteromeric interface reconstituted in homomeric protein.
This study presents a large family with Hereditary hyperekplexia (HH) as a result of homozygous mutation in GLRB.
Hereditary hyperekplexia-causing mutations that modify alpha1 beta GlyR channel function are almost exclusively located in the alpha1 to the exclusion of the beta subunit (show POLG Proteins).
The authors have identified a protein kinase C (PKC) phosphorylation site within the cytoplasmic domain of the beta-subunit of the GlyR (residue S403) that causes a reduction of the binding affinity between the receptor and gephyrin.
A species-specific thymine-to-guanine sequence variation in the Glrb gene has been identified which gives rise to species-specific splice donor sites in the Glrb genes of mouse and bushbaby.
The SdpI (show PACSIN1 Proteins)-binding site was mapped to a proline-rich sequence of 22 amino acids within the intracellular loop of GlyRbeta.
These results show that insulin (show INS Proteins) has a novel regulatory action on the potency of glycine for ionotropic glycine receptors.
Visual stimulation regulates maturation of retinal ganglion cell synaptic activity and connectivity primarily through glycine receptor-mediated synaptic transmission.
This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.
glycine receptor, beta
, glycine receptor subunit beta
, glycine receptor subunit beta-like
, glycine receptor 58 kDa subunit
, glycine receptor, beta subunit
, glycine receptor beta
, inhibitory glycine receptor