Glycine Receptor, beta (GLRB) ELISA Kits

GLRB encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. Additionally we are shipping GLRB Antibodies (43) and GLRB Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human GLRB GLRB 2743 P48167
Anti-Rat GLRB GLRB 25456 P20781
Anti-Mouse GLRB GLRB 14658 P48168
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More ELISA Kits for GLRB Interaction Partners

Human Glycine Receptor, beta (GLRB) interaction partners

  1. Whole-exome sequencing in ASD (show ARSD ELISA Kits) patients from each family identified a second rare inherited genetic variant, affecting GLRB expressed in inhibitory or in excitatory synapses.

  2. GLRA1 (show GLRA1 ELISA Kits) and GLRB mutations are responsible for abnormal startled reactions in humans. (Review)

  3. The N-terminal region of GABRA3 (show GABRA3 ELISA Kits) and the GlyR beta subunit (show POLG ELISA Kits) occupies the same binding site of gephyrin (show GPHN ELISA Kits).

  4. We report novel GLRB mutations in hyperekplexia

  5. Systematic DNA sequencing of GLRB in individuals with hyperekplexia revealed new missense mutations in GLRB, resulting in M177R, L285R and W310C substitutions.

  6. This study describes the definitive assignment of GLRB as the third major gene for hyperekplexia and impacts on the genetic stratification and biological causation of this neonatal/paediatric disorder.

  7. investigated neural progenitor cells in respect to their glycine receptor function and subunit expression using electrophysiology, calcium imaging, immunocytochemistry, and quantitative real-time PCR

  8. Distinct properties of glycine receptor beta+/alpha- interface: unambiguously characterizing heteromeric interface reconstituted in homomeric protein.

  9. This study presents a large family with Hereditary hyperekplexia (HH) as a result of homozygous mutation in GLRB.

  10. Hereditary hyperekplexia-causing mutations that modify alpha1 beta GlyR channel function are almost exclusively located in the alpha1 to the exclusion of the beta subunit (show POLG ELISA Kits).

Mouse (Murine) Glycine Receptor, beta (GLRB) interaction partners

  1. A species-specific thymine-to-guanine sequence variation in the Glrb gene has been identified which gives rise to species-specific splice donor sites in the Glrb genes of mouse and bushbaby.

  2. The SdpI (show PACSIN1 ELISA Kits)-binding site was mapped to a proline-rich sequence of 22 amino acids within the intracellular loop of GlyRbeta.

  3. These results show that insulin (show INS ELISA Kits) has a novel regulatory action on the potency of glycine for ionotropic glycine receptors.

  4. Visual stimulation regulates maturation of retinal ganglion cell synaptic activity and connectivity primarily through glycine receptor-mediated synaptic transmission.

GLRB Antigen Profile

Antigen Summary

This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with GLRB

  • glycine receptor, beta (GLRB) antibody
  • glycine receptor, beta (glrb) antibody
  • glycine receptor, beta (Glrb) antibody
  • glycine receptor, beta subunit (Glrb) antibody
  • AI853901 antibody
  • glrb antibody
  • Glyrb antibody
  • HKPX2 antibody
  • MGC145156 antibody
  • spa antibody
  • spastic antibody

Protein level used designations for GLRB

glycine receptor, beta , glycine receptor subunit beta , glycine receptor subunit beta-like , glycine receptor 58 kDa subunit , glycine receptor, beta subunit , glycine receptor beta , inhibitory glycine receptor

100061981 Equus caballus
461569 Pan troglodytes
700368 Macaca mulatta
779708 Xenopus (Silurana) tropicalis
100172764 Pongo abelii
100392393 Callithrix jacchus
100480924 Ailuropoda melanoleuca
100548283 Meleagris gallopavo
100567921 Anolis carolinensis
100586448 Nomascus leucogenys
281198 Bos taurus
2743 Homo sapiens
25456 Rattus norvegicus
422411 Gallus gallus
475477 Canis lupus familiaris
414284 Sus scrofa
14658 Mus musculus
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