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GPI-linked protein that is a major component of pancreatic zymogen granule membranes. Additionally we are shipping and and many more products for this protein.
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Totals of 12.4% and 20.8% of Crohn's disease patients were positive for IgA/IgG type of anti-GP2 and anti-CUZD1 (show CUZD1 ELISA Kits), respectively. Positivity for anti-pancreatic autoantibodies predicted a faster progression towards complicated disease course.
Anti-GP2 antibody positive CD patients had higher ASCA titres compared to seronegative cases.
A novel role for GP2 in immune regulation could provide a platform for new therapeutic interventions in the treatment of Crohn disease.
GP2 is a binding partner of the scavenger receptor expressed on endothelial cells I (SREC-I (show SCARF1 ELISA Kits)) but not of SR-AI (show MSR1 ELISA Kits) and SR-BI (show SCARB1 ELISA Kits). Dendritic cells express SREC-I (show SCARF1 ELISA Kits) and also bind and internalize GP2.
GP2 gene is unlikely to play a major role in the etiology of chronic pancreatitis.
Data suggest that GP2 alterations do not alter the risk for the development of chronic pancreatitis.
This study represents the first detailed analysis of any variation in the GP2 gene and gives some support to the putative association of c.1275A>G with chronic pancreatitis disease protection.
GP2 binds to Type 1 fimbria, a bacterial adhesin that is commonly expressed by members of the Enterobacteriacae family.
glycoprotein 2 (GP2), specifically expressed on the apical plasma membrane of M cells among enterocytes, serves as a transcytotic receptor for mucosal antigens
GP2-expressing cells in paranasal sinuses are in the lineage of goblet cells.
Tightly linked to homologue THP (show UMOD ELISA Kits). A Gp2 knockout mouse was established which does express THP (show UMOD ELISA Kits).
unlikely that GP2 serves a major intracellular role within the acinar cell, may be active after it is secreted
GPI-linked protein that is a major component of pancreatic zymogen granule membranes
glycoprotein 2 (zymogen granule membrane)
, pancreatic secretory granule membrane major glycoprotein GP2-like
, zymogen granule membrane glycoprotein 2
, pancreatic secretory granule membrane major glycoprotein GP2
, pancreatic zymogen granule membrane associated protein GP2
, pancreatic zymogen granule membrane protein GP-2
, glycoprotein 80
, secretory (zymogen) granule membrane glycoprotein GP2
, zymogen granule membrane protein GP-2