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Glycoprotein Hormones, alpha Polypeptide Proteins (CGA)

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. Additionally we are shipping CGA Antibodies (165) and CGA Kits (26) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CGA 1081 P01215
Rat CGA CGA 116700  
Mouse CGA CGA 12640 P01216
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Top CGA Proteins at antibodies-online.com

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Catalog No. Origin Source Conjugate Quantity Supplier Delivery Price Details
Yeast Macaca fascicularis His tag 1 mg Log in to see 56 to 66 Days
$2,163.33
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CGA Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
, ,
Rat (Rattus)

Mouse (Murine)

Top referenced CGA Proteins

  1. Human CGA Protein expressed in HEK-293 Cells - ABIN2180875 : Fan, Hendrickson: Structure of human follicle-stimulating hormone in complex with its receptor. in Nature 2005 (PubMed)
    Show all 4 references for ABIN2180875

More Proteins for Glycoprotein Hormones, alpha Polypeptide (CGA) Interaction Partners

Human Glycoprotein Hormones, alpha Polypeptide (CGA) interaction partners

  1. The present results have for the first time shown protective effects exerted by hCG on vascular endothelial function.

  2. Human chorionic gonadotropin provides a mechanism to bridge embryo to endometrium through beta1,4-GalT (show GALT Proteins).

  3. TBP (show TBP Proteins) attenuates Msx1 (show MSX1 Proteins)-mediated glycoprotein hormone alpha transcriptional repression.

  4. The results indicate that gal-3 (show LGALS3 Proteins) might be regulated by Human chorionic gonadotropin (hCG)in preparing the endometrium for embryonic implantation.

  5. Limitations in the process of transcription and translation inhibit recombinant human chorionic gonadotropin expression in CHO cells.

  6. the 5-aminoimidazole-4-carboxyamide ribonucleoside (AICAR (show ATIC Proteins))-induced activation of AMPK (show PRKAA1 Proteins) directly inhibited the expression of SREBP-2 (show SREBF2 Proteins) and HMGCR (show HMGCR Proteins) and HMGCS (show HMGCS1 Proteins), and suppressed the TSH-stimulated up-regulation of SREBP-2 (show SREBF2 Proteins) in HepG2 cells.

  7. Serum TSH was associated with pulse wave velocity on population level when adjusted with age and sex.

  8. A single low TSH at baseline was associated with increased risk of hip fractures (adj HR 1.16, 95% CI 1.07-1.26, p < 0.001) but not major osteoporotic fractures (MOF (show KAT8 Proteins), adj HR 1.06, 95% CI 0.99-1.12, p = 0.058) over a median follow-up of 7.5 years.

  9. This study showed a link between low maternal serum hCG levels and cryptorchidism in boys from uncomplicated pregnancy.

  10. A protective effect of hCG against breast cancer may be associated with its growth inhibitory and differentiation induction function in breast cancer cells.

Cow (Bovine) Glycoprotein Hormones, alpha Polypeptide (CGA) interaction partners

  1. These results demonstrate that elevated TSH can promote endothelial dysfunction by altering gene expression in human umbilical vein endothelial cells.

  2. Neurotrophin 4 (show NTF4 Proteins) may have a role in regulating the function of bovine oviducts by interacting with gonadotrophins.

Mouse (Murine) Glycoprotein Hormones, alpha Polypeptide (CGA) interaction partners

  1. Oncogene (show RAB1A Proteins)-induced senescence is initiated in Braf (show BRAF Proteins)(V600E)-induced papillary thyroid cancers when TSH is normal. TSH reduces p53 (show TP53 Proteins) expression by upregulating the PI3K/AKT (show AKT1 Proteins) pathway and inhibiting OIS, resulting in tumor progression.

  2. the Cga eRNA mediates the physical interaction between genomic regions and determines the chromatin structure of the proximal promoter to allow gene expression

  3. Data suggest that highly bioactive luteinizing hormone (LH; both alpha [Cga] and beta [Lhb (show LHB Proteins)] subunits) is produced by embryo/blastocyst at time of implantation; LH bioactivity remains constant in blastocyst on days 5-10 after fertilization.

  4. Disruption of type II deiodinase in thyrotrophs decreases their sensitivity to T4 thyroid hormone and thus elevates serum TSH.

  5. We have identified a post-transcriptional regulatory network active during mouse pituitary development in which the expression of the hormone alphaGSU is increased by let7b/c through downregulation of KSRP (show KHSRP Proteins)

  6. results suggest that in alphaT3-1 cells, dopamine D(2) receptors negatively regulate pituitary gonadotropin alpha subunit (show POLG Proteins) gene expression in association with the cAMP-dependent pathway

  7. These results suggest that ADCYAP1 (show ADCYAP1 Proteins) mainly increases Cga through activation of PKA and MAPK3 (show MAPK3 Proteins)/1, as well as through an additional unknown pathway.

Horse (Equine) Glycoprotein Hormones, alpha Polypeptide (CGA) interaction partners

  1. BMP4 (show BMP4 Proteins) stimulates CG secretion by chorionic girdle trophoblast cells.

CGA Protein Profile

Protein Summary

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CGA

  • glycoprotein hormones, alpha polypeptide (CGA)
  • glycoprotein hormones, alpha polypeptide (Cga)
  • glycoprotein hormones, alpha subunit (Cga)
  • gonadotropin alpha 1subunit (CG)
  • aGSU protein
  • alpha-GSU protein
  • alphaGSU protein
  • alphaSU protein
  • CG-alpha protein
  • CGA protein
  • FSH-alpha protein
  • FSHA protein
  • GPHa protein
  • GPHA1 protein
  • GPHalpha protein
  • HCG protein
  • LHA protein
  • LSH-alpha protein
  • TSH-alpha protein
  • Tsha protein

Protein level used designations for CGA

FSH-alpha , LSH-alpha , TSH-alpha , anterior pituitary glycoprotein hormones common subunit alpha , choriogonadotropin alpha chain , chorionic gonadotrophin subunit alpha , chorionic gonadotropin, alpha polypeptide , follicle-stimulating hormone alpha chain , follicle-stimulating hormone alpha subunit , follitropin alpha chain , glycoprotein hormones alpha chain , luteinizing hormone alpha chain , lutropin alpha chain , thyroid-stimulating hormone alpha chain , thyrotropin alpha chain , glycoprotein hormones, alpha subunit , pituitary hormone alpha subunit , chorionic gonadotropin, alpha chain , TSH alpha , thyrotropin alpha subunit , pituitary glycoprotein hormone alpha subunit , glycoprotein hormone alpha-subunit , LH alpha 3 , precursor polypeptide , Anterior pituitary glycoprotein hormones common subunit alpha , Choriogonadotropin alpha chain , Chorionic gonadotrophin subunit alpha , Follicle-stimulating hormone alpha chain , Follitropin alpha chain , Luteinizing hormone alpha chain , Lutropin alpha chain , Thyroid-stimulating hormone alpha chain , Thyrotropin alpha chain , chorionic gonadotropin alpha , glycoprotein hormones, alpha polypeptide , Glycoprotein hormones alpha chain , glycoprotein hormone alpha subunit , equine chorionic gonadotropin alpha-subunit

GENE ID SPECIES
1081 Homo sapiens
116700 Rattus norvegicus
280749 Bos taurus
751819 Felis catus
403483 Canis lupus familiaris
406869 Sus scrofa
100009481 Oryctolagus cuniculus
443538 Ovis aries
100389264 Callithrix jacchus
100480190 Ailuropoda melanoleuca
100860817 Capra hircus
101835965 Mesocricetus auratus
12640 Mus musculus
100135499 Cavia porcellus
100034174 Equus caballus
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