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Glycoprotein IX (Platelet) Proteins (GP9)

GP9 encodes a small membrane glycoprotein found on the surface of human platelets. Additionally we are shipping CD42a Antibodies (99) and CD42a Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GP9 502858  
GP9 54368 O88186
GP9 2815 P14770
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Top CD42a Proteins at antibodies-online.com

Showing 9 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Rat His tag,GST tag 100 μg Log in to see 11 to 13 Days
$844.80
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

GP9 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Mouse (Murine) ,
,
Human , , ,
, ,

Top referenced CD42a Proteins

  1. Human CD42a Protein expressed in Escherichia coli (E. coli) - ABIN1098751 : McEwan, Yang, Carr, Mo, Zheng, Li, Emsley: Quaternary organization of GPIb-IX complex and insights into Bernard-Soulier syndrome revealed by the structures of GPIbβ and a GPIbβ/GPIX chimera. in Blood 2011 (PubMed)
    Show all 2 references for ABIN1098751

More Proteins for Glycoprotein IX (Platelet) (GP9) Interaction Partners

Mouse (Murine) Glycoprotein IX (Platelet) (GP9) interaction partners

  1. A Lyn-Vav-Rac1-PI3K-Akt pathway mediates von Willebrand factor-induced activation of integrin alpha(IIb)beta(3) to promote GPIb-IX-dependent platelet activation.

  2. Data indicate that GPIX is the subunit of the glycoprotein Ib-IX-V complex that binds to grp94/Hsp90b1 (show HSP90B1 Proteins); the glycoprotein Ib-IX-V complex is stabilized by grp94/Hsp90b1 (show HSP90B1 Proteins).

Human Glycoprotein IX (Platelet) (GP9) interaction partners

  1. factor XI is localized to GPIb in membrane rafts and this association is important for promoting the activation of factor XI by thrombin (show F2 Proteins) on the platelet surface

  2. Data show that localization of the GP Ib-IX complex to the lipid domain is mediated by GP Ibbeta and GP IX transmembrane domains.

  3. genetic association study in population in western India: Data suggest novel mutations in platelet glycoprotein Ib (GP1BA (show GP1BA Proteins), GP1BB (show GP1BB Proteins)) and GP9 are associated with Bernard-Soulier syndrome in subjects studies; of 12 mutations identified, ten were novel.

  4. Studies indicate that platelets from Bernard-Soulier syndrome (BSS) are defective in glycoprotein (GP)Ib-IX-V, a platelet-specific adhesion-signaling complex, composed of GPIbalpha disulfide linked to GPIbbeta, and noncovalently associated with GPIX and GPV.

  5. GPIX increased the expression of GPIba by promoting the formation of a disulfide bond between GPIba and GPIbb in transfected CHO-K1 cells.

  6. GPIbbeta missense mutations from Bernard-Soulier syndrome were examined for changes to GPIb-IX complex surface expression. Mutations A108P and P74R were found to maintain normal secretion/folding of GPIbbeta(E) but were unable to support GPIX surface expression

  7. GPIIb/IIIa is the primary receptor set involved in platelet adhesion to adsorbed fibrinogen and serum albumin (show ALB Proteins) irrespective of their degree of adsorption-induced unfolding, while the GPIb-IX-V receptor complex plays an insignificant role.

  8. GP Ibbeta/GP IX mediates the disulfide-linked GP Ibalpha localization to the GEMs, which is critical for vWf (show VWF Proteins) interaction at high shear

  9. 14-3-3beta, 14-3-3gamma, 14-3-3epsilon, 14-3-3eta and 14-3-3theta isoforms interact with the GPIb-IX complex in platelets

  10. the putative convex surface of the LRR domain in GPIX is sufficient, in the context of full-length subunit, to mediate its association with GPIbbeta

CD42a (GP9) Protein Profile

Protein Summary

This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.

Gene names and symbols associated with GP9

  • glycoprotein IX (platelet) (GP9)
  • glycoprotein IX (platelet) (gp9)
  • glycoprotein IX (platelet) (Gp9)
  • glycoprotein IX (platelet) (LOC100340400)
  • glycoprotein 9 (platelet) (Gp9)
  • Cd42 protein
  • CD42a protein
  • GP9 protein
  • GPIX protein

Protein level used designations for GP9

glycoprotein IX (platelet) , glycoprotein 9 (platelet) , platelet glycoprotein IX , GP-IX , glycoprotein 9

GENE ID SPECIES
415971 Gallus gallus
447392 Xenopus laevis
502858 Rattus norvegicus
609630 Canis lupus familiaris
617668 Bos taurus
704202 Macaca mulatta
737968 Pan troglodytes
100216312 Sus scrofa
100340400 Oryctolagus cuniculus
54368 Mus musculus
2815 Homo sapiens
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