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anti-Glycoprotein V (Platelet) (GP5) Antibodies

Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. Additionally we are shipping GP5 Kits (33) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GP5 14729  
GP5 25259 O08770
GP5 2814 P40197
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Top anti-GP5 Antibodies at antibodies-online.com

Showing 10 out of 32 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated Func, IF   1 mL Log in to see 6 to 8 Days
$632.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of expression in Jurkat cell lysante (Lane 1,2 ) 100 μg Log in to see 2 to 3 Days
$283.50
Details
Mouse Armenian Hamster APC ICFC 100 μg Log in to see 10 to 12 Days
$298.95
Details
Mouse Armenian Hamster PerCP-Cy5.5 FACS 100 μg Log in to see 10 to 12 Days
$320.68
Details
Mouse Armenian Hamster PE FACS 100 μg Log in to see 10 to 12 Days
$190.24
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Armenian Hamster Un-conjugated FACS 500 μg Log in to see 10 to 12 Days
$288.07
Details
Mouse Armenian Hamster PerCP-eFluor® 710 FACS 100 μg Log in to see 5 to 6 Days
$343.70
Details
Mouse Hamster APC FACS 100 μg Log in to see 8 to 10 Days
$595.83
Details
Mouse Armenian Hamster Un-conjugated IHC (fro), FACS, IF, IP   0.5 mg Log in to see 5 to 6 Days
$460.88
Details

GP5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GP5 Antibodies

  1. Mouse (Murine) Monoclonal GP5 Primary Antibody for FACS - ABIN2664689 : Andrews, Harris, McNally, Berndt: Binding of purified 14-3-3 zeta signaling protein to discrete amino acid sequences within the cytoplasmic domain of the platelet membrane glycoprotein Ib-IX-V complex. in Biochemistry 1998 (PubMed)
    Show all 11 references for ABIN2664689

  2. Mouse (Murine) Monoclonal GP5 Primary Antibody for FACS - ABIN2660118 : Hickey, Hagen, Yagi, Roth: Human platelet glycoprotein V: characterization of the polypeptide and the related Ib-V-IX receptor system of adhesive, leucine-rich glycoproteins. in Proceedings of the National Academy of Sciences of the United States of America 1993 (PubMed)
    Show all 11 references for ABIN2660118

  3. Mouse (Murine) Monoclonal GP5 Primary Antibody for FACS - ABIN2662644 : Inoue, Suzuki-Inoue, Ozaki: Redundant mechanism of platelet adhesion to laminin and collagen under flow: involvement of von Willebrand factor and glycoprotein Ib-IX-V. in The Journal of biological chemistry 2008 (PubMed)
    Show all 11 references for ABIN2662644

  4. Mouse (Murine) Monoclonal GP5 Primary Antibody for ICFC - ABIN2658230 : Ravanat, Morales, Azorsa, Moog, Schuhler, Grunert, Loew, Van Dorsselaer, Cazenave, Lanza: Gene cloning of rat and mouse platelet glycoprotein V: identification of megakaryocyte-specific promoters and demonstration of functional thrombin cleavage. in Blood 1997 (PubMed)
    Show all 11 references for ABIN2658230

  5. Mouse (Murine) Monoclonal GP5 Primary Antibody for IHC (fro), FACS - ABIN2689254 : Sato, Kiyokawa, Taguchi, Suzuki, Sekino, Ohmi, Itagaki, Sato, Lepage, Lanza, Fujimoto: Functional conservation of platelet glycoprotein V promoter between mouse and human megakaryocytes. in Experimental hematology 2000 (PubMed)
    Show all 4 references for ABIN2689254

  6. Human Monoclonal GP5 Primary Antibody for Func, IF - ABIN1106368 : Modderman, Admiraal, Sonnenberg, von dem Borne: Glycoproteins V and Ib-IX form a noncovalent complex in the platelet membrane. in The Journal of biological chemistry 1992 (PubMed)
    Show all 3 references for ABIN1106368

  7. Mouse (Murine) Monoclonal GP5 Primary Antibody for FACS - ABIN2678951 : Takada, Saito, Kaneko, Iizuka, Kokai, Fujimoto: Novel monoclonal antibody reactive with thrombin-sensitive 74-kDa glycoproteins present on platelets and megakaryocytes both from mouse and rat. in Hybridoma 1996 (PubMed)

More Antibodies against GP5 Interaction Partners

Mouse (Murine) Glycoprotein V (Platelet) (GP5) interaction partners

  1. Desialylation of platelet VWFR therefore triggers platelet clearance and primes GPIbalpha (show GP1BA Antibodies) and GPV for MP-dependent cleavage.

  2. GPV is cleaved upon agonist-induced platelet activation, with ADAM17 (show ADAM17 Antibodies) as the major enzyme mediating this process

  3. GPIbalpha (show GP1BA Antibodies) and GPV are shed through an ADAM17 (show ADAM17 Antibodies)-dependent mechanism after aspirin administration

  4. ROLE OF GPV IN HEMOSTASIS AND THROMBOSIS IS PROBABLY OF LESSER IMPORTANCE THAN PREVIOUSLY THOUGHT

Human Glycoprotein V (Platelet) (GP5) interaction partners

  1. Studies indicate that platelets from Bernard-Soulier syndrome (BSS (show GP1BA Antibodies)) are defective in glycoprotein (GP)Ib-IX-V, a platelet-specific adhesion-signaling complex, composed of GPIbalpha (show GP1BA Antibodies) disulfide linked to GPIbbeta, and noncovalently associated with GPIX (show GP9 Antibodies) and GPV.

  2. GPIIb (show ITGA2B Antibodies)/IIIa is the primary receptor set involved in platelet adhesion to adsorbed fibrinogen and serum albumin (show ALB Antibodies) irrespective of their degree of adsorption-induced unfolding, while the GPIb-IX-V receptor complex plays an insignificant role.

  3. Both the high affinity thrombin receptor (show F2R Antibodies) (GPIb-IX-V) and GPIIb (show ITGA2B Antibodies)/IIIa are implicated in expression of thrombin (show F2 Antibodies)-induced platelet procoagulant activity.

  4. GPV is cleaved upon agonist-induced platelet activation, with ADAM17 (show ADAM17 Antibodies) as the major enzyme mediating this process

  5. GPIbalpha (show GP1BA Antibodies) and GPV are shed through an ADAM17 (show ADAM17 Antibodies)-dependent mechanism after aspirin administration

  6. laminin supports platelet adhesion depending on the interaction of VWF (show VWF Antibodies) and GPIb-IX-V under pathophysiological high shear flow

  7. glycoprotein Ib-IX-V complex contributes to tissue factor (show F3 Antibodies)-independent thrombin (show F2 Antibodies) generation by recombinant factor VIIa on the activated platelet surface

GP5 Antigen Profile

Protein Summary

Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998

Gene names and symbols associated with GP5

  • glycoprotein V (platelet) (gp5) antibody
  • glycoprotein V (platelet) (GP5) antibody
  • glycoprotein 5 (platelet) (Gp5) antibody
  • glycoprotein V (platelet) (Gp5) antibody
  • CD42d antibody
  • GPV antibody
  • lib antibody
  • PLGPV antibody

Protein level used designations for GP5

glycoprotein 5 (platelet) , platelet glycoprotein V , glycoprotein V (platelet) , platelet glycoprotein V-like , GPV , Platelet glycoprotein 5 , Platelete glycoprotein 5 , glycoprotein 5, platelet , glycoprotein 5

GENE ID SPECIES
446839 Xenopus laevis
522692 Bos taurus
707776 Macaca mulatta
741837 Pan troglodytes
100060025 Equus caballus
100457049 Pongo abelii
14729 Mus musculus
25259 Rattus norvegicus
2814 Homo sapiens
100718244 Cavia porcellus
768872 Gallus gallus
101103118 Ovis aries
Selected quality suppliers for anti-GP5 (GP5) Antibodies
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