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GTDC2 encodes a protein with glycosyltransferase activity although its function is not currently known. Additionally we are shipping Glycosyltransferase-Like Domain Containing 2 Antibodies (25) and many more products for this protein.
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AGO61-KO mice lacked laminin-binding glycans and exhibited phenotypes similar to those of known dystroglycanopathy mutants, as reflected by abnormalities in neural migration and basal lamina formation.
GTDC2 generates CTD110.6 antibody-reactive N-acetylglucosamine epitopes on the O-mannosylated alpha-dystroglycan.
Using WES in consanguineous WWS-affected families, we found multiple deleterious mutations in GTDC2 (also known as AGO61). .
This gene encodes a protein with glycosyltransferase activity although its function is not currently known.
extracellular O-linked N-acetylglucosamine transferase-like
, glycosyltransferase-like domain-containing protein 2
, glycosyltransferase ago61
, glycosyltransferase-like domain containing 2