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Glycyl-tRNA Synthetase (GARS) ELISA Kits

GARS encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. Additionally we are shipping Glycyl-tRNA Synthetase Antibodies (61) and Glycyl-tRNA Synthetase Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GARS 2617 P41250
Anti-Mouse GARS GARS 353172 Q9CZD3
Anti-Rat GARS GARS 297113  
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Top Glycyl-tRNA Synthetase ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.062 ng/mL 15.63-1000 pg/mL 96 Tests Log in to see 9 to 11 Days
$736.84
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Pig
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$770.00
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Monkey
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$770.00
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Chicken
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$770.00
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Rabbit
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$770.00
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More ELISA Kits for Glycyl-tRNA Synthetase Interaction Partners

Fruit Fly (Drosophila melanogaster) Glycyl-tRNA Synthetase (GARS) interaction partners

  1. Our findings suggest that mutant GlyRS gains access to ectopic sub-compartments of the motor neuron, providing a possible explanation for the selective neuropathology caused by mutations in a widely expressed gene.

Human Glycyl-tRNA Synthetase (GARS) interaction partners

  1. one of the mRNAs isoforms tightly controls expression and localization of human GARS.

  2. This study reports two crystal structures of human GlyRS variants, in the free form and in complex with tRNA(Gly) respectively, and reveal new aspects of the glycylation mechanism.

  3. GARS mutations are an uncommon cause of Charcot-Marie-Tooth Disease (CMT) in Taiwan. The p.Asp146Tyr and p.Met238Arg mutations are associated with early-onset axonal CMT.

  4. Our findings suggest that mutant GlyRS gains access to ectopic sub-compartments of the motor neuron, providing a possible explanation for the selective neuropathology caused by mutations in a widely expressed gene.

  5. Expression of three CMT-mutant GARS proteins in Drosophila induces defects in motor performance and motor and sensory neuron morphology, and shortens lifespan.

  6. The c.999G>T mutation is a novel mutation of the glycyl-tRNA synthetase gene that has not been previously reported. The phenotype of this family is Charcot-Marie-Tooth disease type 2D, which is first reported in Chinese population.

  7. we propose that the disease-causing L129P mutant of glycyl-tRNA synthetase is linked to a distribution defect in peripheral nerves in vivo.

  8. our data indicate that impaired function is a key component of GARS-mediated CMT disease and emphasize the need for careful genetic and functional evaluation before implicating a variant in disease onset.

  9. We developed an ELISA to detect anti-glycyl-tRNA synthetase by using recombinant protein

  10. Report crystal structures of wild type and mutant GlyRS in complex with tRNA and with small substrates and describe the molecular details of enzymatic recognition of the key tRNA identity elements in the acceptor stem and the anticodon loop.

Mouse (Murine) Glycyl-tRNA Synthetase (GARS) interaction partners

  1. findings link the selective pathology of Charcot-Marie-Tooth disease type 2D to the neomorphic binding activity of GlyRS(CMT2D) that antagonizes the VEGF (show VEGFA ELISA Kits)-Nrp1 (show NRP1 ELISA Kits) interaction, meaning the VEGF (show VEGFA ELISA Kits)-Nrp1 (show NRP1 ELISA Kits) signalling axis is an actionable target for treating CMT2D

  2. Results indicate that Charcot-Marie-Tooth peripheral neuropathies, type 2D (CMT2D) phenotype is caused by novel pathogenic roles for the mutant GARS that specifically affect peripheral neurons.

  3. a glycyl-tRNA synthetase (GARS) mutation causes peripheral sensory and motor phenotypes creating a model of Charcot-Marie-Tooth type 2D peripheral neuropathy

  4. Gars(C201R) mutation significantly delayed disease onset in the SOD1 (show SOD1 ELISA Kits)(G93A);Gars(C201R/+) double heterozygous mutant mice and increased lifespan by 29% on the genetic background investigated

Pig (Porcine) Glycyl-tRNA Synthetase (GARS) interaction partners

  1. Expression levels of ADSL (show ADSL ELISA Kits), GARS-AIRS-GART (show GART ELISA Kits), and DGAT1 (show DGAT1 ELISA Kits) were higher in longissimus lumborum muscle than in heart or liver tissues

Glycyl-tRNA Synthetase (GARS) Antigen Profile

Antigen Summary

This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.

Gene names and symbols associated with GARS

  • Glycyl-tRNA synthetase (Aats-gly) antibody
  • glycyl-tRNA synthetase (Aats-gly) antibody
  • glycyl-tRNA synthetase (GARS) antibody
  • glycyl-tRNA synthetase (gars) antibody
  • glycyl-tRNA synthetase (glyQ) antibody
  • glycyl-tRNA synthetase (TTHA0543) antibody
  • glycyl-tRNA synthetase (Gars) antibody
  • glycyl-tRNA synthetase (LOC692991) antibody
  • glycyl-tRNA synthetase-like (LOC100512260) antibody
  • Aat-gly antibody
  • CG6778 antibody
  • CMT2D antibody
  • Dmel\\CG6778 antibody
  • DSMAV antibody
  • fb02f03 antibody
  • gars antibody
  • GB13467 antibody
  • Gena201 antibody
  • GENA202 antibody
  • GlyRS antibody
  • GRS antibody
  • HMN5 antibody
  • MGC79495 antibody
  • Nmf249 antibody
  • RGD1559871 antibody
  • Sgrp23 antibody
  • si:dkey-276i5.1 antibody
  • SMAD1 antibody
  • team antibody
  • wu:fb02f03 antibody

Protein level used designations for GARS

Aats-gly-PA , Aats-gly-PB , Aats-gly-PC , CG6778-PA , CG6778-PB , CG6778-PC , glycyl-tRNA synthetase , glycine--tRNA ligase , AP-4-A synthetase , Charcot-Marie-Tooth neuropathy 2D , Charcot-Marie-Tooth neuropathy, neuronal type, D , diadenosine tetraphosphate synthetase , glycine tRNA ligase , glyRS , storage granule protein 23 , glycyl-tran synthetase

GENE ID SPECIES
39644 Drosophila melanogaster
408392 Apis mellifera
463329 Pan troglodytes
475268 Canis lupus familiaris
493218 Xenopus (Silurana) tropicalis
884595 Chlamydia trachomatis D/UW-3/CX
3169948 Thermus thermophilus HB8
100388470 Callithrix jacchus
2617 Homo sapiens
353172 Mus musculus
297113 Rattus norvegicus
337230 Danio rerio
446482 Xenopus laevis
428403 Gallus gallus
408010 Bos taurus
692991 Bombyx mori
100174405 Pongo abelii
100512260 Sus scrofa
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