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Glyoxalase I Proteins (GLO1)

The enzyme encoded by GLO1 is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Additionally we are shipping Glyoxalase I Antibodies (95) and Glyoxalase I Kits (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GLO1 109801 Q9CPU0
Rat GLO1 GLO1 294320 Q6P7Q4
GLO1 2739 Q04760
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Top Glyoxalase I Proteins at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 2 to 3 Days
$309.75
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 7 to 8 Days
$242.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$788.70
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Shigella flexneri His tag   1 mg Log in to see 56 to 66 Days
$2,284.33
Details
Yeast Pseudomonas putida His tag   1 mg Log in to see 56 to 66 Days
$2,398.00
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$2,432.83
Details

GLO1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

Top referenced Glyoxalase I Proteins

  1. Human GLO1 Protein expressed in Escherichia coli (E. coli) - ABIN666885 : Ridderström, Mannervik: Optimized heterologous expression of the human zinc enzyme glyoxalase I. in The Biochemical journal 1996 (PubMed)
    Show all 2 references for ABIN666885

More Proteins for Glyoxalase I (GLO1) Interaction Partners

Mouse (Murine) Glyoxalase I (GLO1) interaction partners

  1. Glo1 knockdown does not have major short term effects on the energy expenditure or the formation of atherosclerotic plaques.

  2. Crystal structure of the mouse Glo1-inhibitor complex was determined at 2.3 A resolution.

  3. Study demonstrates that GLO1 is a novel metabolic oncogene (show RAB1A Proteins) of the 6p21 amplicon, which promotes tumor growth and aberrant transcriptional signals via regulating cellular metabolic activities for energy production.

  4. the balance between methylglyoxal and age-dependent GLO1 downregulation contributes to delayed wound healing in old mice

  5. The difference in glyoxalase-1 mRNA was observed with Fkbp5 (show FKBP5 Proteins)-/- mice expressing 2-fold more glyoxylase-1 protein.

  6. pharmacological inhibition of GLO1 reduced anxiety, suggesting that GLO1 is a possible target for the treatment of anxiety disorders.

  7. These results suggest that GLO-1 plays a role in high glucose-mediated signaling by reducing mesangial cells accumulation and oxidative stress in diabetes mellitus.

  8. Findings reveal that the abundance of GLO1 varies between different murine strains and within different sensory neuron populations.

  9. Data show that reducing RGS2 (show RGS2 Proteins) expression by antisense treatment prevented the increase in GLO1 and GSR1 (show GSR Proteins) mRNA and protein expression.

  10. Data demonstrate GLO1 expression and glycation damage to be induced by alpha-synuclein ablation leading to the suggestion that wild-type alpha-synuclein modulates brain glucose metabolism.

Human Glyoxalase I (GLO1) interaction partners

  1. Data suggest Glo1's effects on anxiety-like behavior are centrally mediated as overexpression of Glo1 in neurons was sufficient to increase anxiety-like behavior

  2. Studies indicate that the most extensively investigated The most extensively investigated glyoxalase enzymes are glyoxalase I and glyoxalase II (show HAGH Proteins) (Glo1 and Glo2 (show HAGH Proteins)).

  3. The GLO1 variations were not the source of association of the BTBD9 (show BTBD9 Proteins) locus with restless legs syndrome.

  4. Glo1 is involved in the Min-U-Sil 5 crystalline silica-induced BEAS-2B cell mitochondrial apoptotic pathway.

  5. GLO1 activity affects the overall burden of carotid artery atherosclerosis.

  6. individuals with the GLO1 A /E genotype, PON192/QR-RR genotypes and PON55/LM-MM genotypes had a significantly higher risk of cerebral cavernous malformations compared with the other genotypes.

  7. This study demonstrated that the GLO1 C332 (Ala111) allele confers autism vulnerability by reducing brain glyoxalase activity and enhancing advanced glycation end-products. formation

  8. This review describes the role of GLO1 in tumor cell proliferation and survival, and the potential of GLO1 as a biomarker for tumor diagnosis and as a target for anticancer drug development. [review]

  9. Significant differences in the allelic and genotype frequencies of GLO1.

  10. In ApoE (show APOE Proteins)(-/-) mice with or without diabetes, GLO1 overexpression did not lead to decreased atherosclerotic lesion size or systemic inflammation.

Glyoxalase I (GLO1) Protein Profile

Protein Summary

The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere.

Gene names and symbols associated with Glyoxalase I Proteins (GLO1)

  • glyoxalase 1 (glo1)
  • glyoxalase I (GLO1)
  • glyoxalase 1 (glo1-b)
  • glyoxalase 1 (glo1-a)
  • lactoylglutathione lyase (glyoxalase I)
  • glyoxalase I homolog (GLX1)
  • glyoxalase I (gloA)
  • glyoxalase I (Bcen_2094)
  • glyoxalase 1 (Glo1)
  • glyoxalase I (Glo1)
  • 0610009E22Rik protein
  • 1110008E19Rik protein
  • 2510049H23Rik protein
  • ATGLX1 protein
  • AW550643 protein
  • cb554 protein
  • F12F1.32 protein
  • F12F1_32 protein
  • Glo-1 protein
  • Glo-1r protein
  • Glo-1s protein
  • GLO1 protein
  • Glo1-r protein
  • Glo1-s protein
  • GLOD1 protein
  • GLY1 protein
  • GLYI protein
  • GLYOXALASE I protein
  • glyoxalase I homolog protein
  • Qglo protein
  • trypanothione-dependent glyoxalase I protein
  • wu:fb82g09 protein
  • zgc:66035 protein

Protein level used designations for Glyoxalase I Proteins (GLO1)

lactoylglutathione lyase , glyoxalase I , hypothetical protein , trypanothione-dependent glyoxalase I , S-D-lactoylglutathione methylglyoxal lyase , aldoketomutase , glx I , glyoxalase 1 complex , glyoxalase 1 regulatory , glyoxalase 1 structural , ketone-aldehyde mutase , methylglyoxalase , glyoxylase 1 , glyoxalase domain containing 1 , lactoyl glutathione lyase

GENE ID SPECIES
368213 Danio rerio
421428 Gallus gallus
446359 Xenopus laevis
447401 Xenopus laevis
547925 Glycine max
594942 Xenopus (Silurana) tropicalis
719518 Macaca mulatta
748215 Pan troglodytes
837731 Arabidopsis thaliana
1248061 Salmonella enterica subsp. enterica serovar Typhi str. CT18
3639312 Candida albicans SC5314
3639398 Candida albicans SC5314
4091104 Burkholderia cenocepacia AU 1054
4850985 Scheffersomyces stipitis CBS 6054
5073200 Leishmania infantum JPCM5
6924240 Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91
6949741 Salmonella enterica subsp. enterica serovar Enteritidis str. P125109
109801 Mus musculus
294320 Rattus norvegicus
2739 Homo sapiens
474894 Canis lupus familiaris
100156085 Sus scrofa
540335 Bos taurus
100726491 Cavia porcellus
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