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Glypican 3 (GPC3) ELISA Kits

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Additionally we are shipping Glypican 3 Antibodies (171) and Glypican 3 Proteins (13) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GPC3 2719 P51654
GPC3 14734 Q8CFZ4
GPC3 25236 P13265
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Top Glypican 3 ELISA Kits at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.063 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$663.16
Details
Rat 0.055 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$720.00
Details
Mouse 0.78 ng/ml 3.12-200 ng/mL   96 Tests Log in to see 9 to 11 Days
$910.56
Details
Rabbit 0.1 ng/mL 1-25 ng/mL   96 Tests Log in to see 11 to 13 Days
$785.71
Details
Guinea Pig
  96 Tests Log in to see 11 to 13 Days
$801.43
Details
Pig
  96 Tests Log in to see 8 to 9 Days
$770.00
Details
Chicken
  96 Tests Log in to see 8 to 9 Days
$770.00
Details
Monkey
  96 Tests Log in to see 8 to 9 Days
$770.00
Details
Dog
  96 Tests Log in to see 11 to 13 Days
$801.43
Details
Goat
  96 Tests Log in to see 11 to 13 Days
$801.43
Details

Top referenced Glypican 3 ELISA Kits

  1. Human Glypican 3 ELISA Kit for Sandwich ELISA - ABIN414787 : Tangkijvanich, Chanmee, Komtong, Mahachai, Wisedopas, Pothacharoen, Kongtawelert: Diagnostic role of serum glypican-3 in differentiating hepatocellular carcinoma from non-malignant chronic liver disease and other liver cancers. in Journal of gastroenterology and hepatology 2010 (PubMed)
    Show all 5 references for ABIN414787

More ELISA Kits for Glypican 3 Interaction Partners

Human Glypican 3 (GPC3) interaction partners

  1. GPC3 expression was measured in hepatocellular carcinoma at different stages and correlated with prognosis. CK19 (show KRT19 ELISA Kits)+/GPC3+ HCC (show FAM126A ELISA Kits) has the highest risk of intrahepatic metastasis, microvascular invasion, regional lymph node involvement, and distant metastasis.

  2. Review: Glypican-3 is a highly specific biomarker for the diagnosis of hepatocellular carcinoma and a promising therapeutic target.

  3. In South Korean hepatocellular carcinoma patients, GPC3 expression was more frequent in hepatocellular carcinoma with aggressive features, but it was not an independent prognostic biomarker.

  4. In this meta-analysis, GPC3 was found to be acceptable as a serum marker for the diagnosis of hepatocellular carcinoma.

  5. GPC3 may be a candidate marker for detecting lung squamous cell carcinoma.

  6. study suggests that GPC3 is involved in HCC (show FAM126A ELISA Kits) cell migration and motility through HS chain-mediated cooperation with the HGF (show HGF ELISA Kits)/Met pathway, showing how HS targeting has potential therapeutic implications for liver cancer

  7. potential role of GPC3 in urothelial carcinogenesis warrants further investigation, especially the potential use of Glypican-3 for therapeutic and diagnostic purposes

  8. Downregulation of glypican-3 expression increases migration, invasion, and tumorigenicity of ovarian cancer.

  9. GPC3 expression is an independent prognostic factor for postoperative hepatocellular carcinoma

  10. Identify a GPC3-specific T-cell receptor. Expression of this receptor by T cells allows them to recognize and kill GPC3-positive hepatoma cells.

Mouse (Murine) Glypican 3 (GPC3) interaction partners

  1. Coupling of pGPC3 to liposomes was essential for effective priming of GPC3-specific CTLs.

  2. The expression of GPC-3 was altered by DEN treatment.

  3. Data suggest that GPC3 down-regulates hepatocyte proliferation by binding to hedgehog (show SHH ELISA Kits) (HH) and down-regulating the HH signaling pathway and binding with CD81 (show CD81 ELISA Kits), thus making it unavailable to bind to Hhex (show HHEX ELISA Kits) and causing its nuclear translocation.

  4. Finding represents a rare four layer genomic overlap consisting of growth associated quantitative trait locus (QTL), body mass associated Gpc3 gene, highly conserved miRNA gene and mature miRNA seed SNP identified in the lean mouse.

  5. Hepatocyte overexpression of GPC3 suppresses hepatocyte proliferation and liver regeneration and alters gene expression profiles.

  6. glypican-3 is involved in the recruitment of M2-polarized tumor-associated macrophages in hepatocellular carcinoma

  7. GPC3 inhibits the PI3K/Akt (show AKT1 ELISA Kits) anti-apoptotic pathway while it stimulates the p38MAPK (show MAPK14 ELISA Kits) stress-activated one in murine mammary adenocarcinoma LM3 cells

  8. Gpc3 function in development of Simpson-Golabi-Behmel syndrome is IGF-independent

  9. GPC3 knockout mice exhibit alterations in the Wnt (show WNT2 ELISA Kits) signaling pathway, which is also associated with the regulation of cell proliferation

  10. Polymorphisms in the 3' untranslated region of Gpc3 are strong candidates for the causal sequence variation and loss-of-function mutations can cause overgrowth and developmental abnormalities.

Glypican 3 (GPC3) Antigen Profile

Antigen Summary

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with Glypican 3 (GPC3) ELISA Kits

  • glypican 3 (gpc3) antibody
  • glypican 3 (GPC3) antibody
  • glypican 3 (Gpc3) antibody
  • DGSX antibody
  • Glypican-3 antibody
  • GPC3 antibody
  • GTR2-2 antibody
  • MXR7 antibody
  • OCI-5 antibody
  • SDYS antibody
  • SGB antibody
  • SGBS antibody
  • SGBS1 antibody

Protein level used designations for Glypican 3 (GPC3) ELISA Kits

glypican 3 , glypican-3-like , glypican proteoglycan 3 , glypican-3 , heparan sulphate proteoglycan , intestinal protein OCI-5 , secreted glypican-3 , defective in Simpson-Golabi-Behmel overgrowth syndrome , proteoglycan GPC3 , Intestinal protein OCI-5

GENE ID SPECIES
387365 Danio rerio
706773 Macaca mulatta
100023253 Monodelphis domestica
100135027 Xenopus (Silurana) tropicalis
100401118 Callithrix jacchus
100444952 Pongo abelii
100477314 Ailuropoda melanoleuca
100548246 Meleagris gallopavo
100591673 Nomascus leucogenys
2719 Homo sapiens
481056 Canis lupus familiaris
615239 Bos taurus
14734 Mus musculus
25236 Rattus norvegicus
100351858 Oryctolagus cuniculus
100726246 Cavia porcellus
100516171 Sus scrofa
770863 Gallus gallus
101119285 Ovis aries
465866 Pan troglodytes
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