Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Additionally we are shipping Glypican 3 Antibodies (341) and Glypican 3 Proteins (25) and many more products for this protein.
Showing 10 out of 49 products:
Human Glypican 3 ELISA Kit for Sandwich ELISA - ABIN365731
Yao, Yao, Bian, Wu, Yan, Yu, Qiu, Yang, Zhang, Sai, Chen: Values of circulating GPC-3 mRNA and alpha-fetoprotein in detecting patients with hepatocellular carcinoma. in Hepatobiliary & pancreatic diseases international : HBPD INT 2013
Show all 3 references for ABIN365731
This is the first study in which the optimal HLA-A*0201 GPC3 epitopes were screened from a large number of candidates predicted by three software. The optimized HLA-A*0201 GPC3 peptides will provide new epitope candidates for hepatocellular carcinoma (HCC (show FAM126A ELISA Kits)) immunotherapy.
GPC3 and KRT19 (show KRT19 ELISA Kits) overexpression are associated with carcinogenesis, progression, and poor prognosis in patients with PDAC and a valuable biomarker for diagnosis of PDAC.
The clinical implication of GPC3 detection and targeting in the management of patients with hepatocellular carcinoma. Review.
Glypican 3 expression showed a significant difference between endometrioid endometrial carcinoma and serous endometrial carcinoma, and it was significantly correlated with tumor grade, stage and myometrial invasion
Data show that notum (show NOTUM ELISA Kits) and glypican-1 (show GPC1 ELISA Kits) and glypican-3 gene expression during colorectal cancer (CRC (show CALR ELISA Kits)) development and present evidence to suggest them as potential new biomarkers of CRC (show CALR ELISA Kits) pathogenesis.
GPC3 expression was measured in hepatocellular carcinoma at different stages and correlated with prognosis. CK19 (show KRT19 ELISA Kits)+/GPC3+ HCC (show FAM126A ELISA Kits) has the highest risk of intrahepatic metastasis, microvascular invasion, regional lymph node involvement, and distant metastasis.
Review: Glypican-3 is a highly specific biomarker for the diagnosis of hepatocellular carcinoma and a promising therapeutic target.
In South Korean hepatocellular carcinoma patients, GPC3 expression was more frequent in hepatocellular carcinoma with aggressive features, but it was not an independent prognostic biomarker.
In this meta-analysis, GPC3 was found to be acceptable as a serum marker for the diagnosis of hepatocellular carcinoma.
GPC3 may be a candidate marker for detecting lung squamous cell carcinoma.
Data show that notum (show NOTUM ELISA Kits) and glypican-1 (show GPC1 ELISA Kits) and glypican-3 gene expression during colorectal cancer (CRC (show SCRIB ELISA Kits)) development and present evidence to suggest them as potential new biomarkers of CRC (show SCRIB ELISA Kits) pathogenesis.
Coupling of pGPC3 to liposomes was essential for effective priming of GPC3-specific CTLs.
The expression of GPC-3 was altered by DEN treatment.
Data suggest that GPC3 down-regulates hepatocyte proliferation by binding to hedgehog (show SHH ELISA Kits) (HH) and down-regulating the HH signaling pathway and binding with CD81 (show CD81 ELISA Kits), thus making it unavailable to bind to Hhex (show HHEX ELISA Kits) and causing its nuclear translocation.
Finding represents a rare four layer genomic overlap consisting of growth associated quantitative trait locus (QTL), body mass associated Gpc3 gene, highly conserved miRNA gene and mature miRNA seed SNP identified in the lean mouse.
Hepatocyte overexpression of GPC3 suppresses hepatocyte proliferation and liver regeneration and alters gene expression profiles.
glypican-3 is involved in the recruitment of M2-polarized tumor-associated macrophages in hepatocellular carcinoma
GPC3 inhibits the PI3K/Akt (show AKT1 ELISA Kits) anti-apoptotic pathway while it stimulates the p38MAPK (show MAPK14 ELISA Kits) stress-activated one in murine mammary adenocarcinoma LM3 cells
Gpc3 function in development of Simpson-Golabi-Behmel syndrome is IGF-independent
GPC3 knockout mice exhibit alterations in the Wnt (show WNT2 ELISA Kits) signaling pathway, which is also associated with the regulation of cell proliferation
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.
, glypican proteoglycan 3
, heparan sulphate proteoglycan
, intestinal protein OCI-5
, secreted glypican-3
, defective in Simpson-Golabi-Behmel overgrowth syndrome
, proteoglycan GPC3
, Intestinal protein OCI-5