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The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. Additionally we are shipping Golgi Membrane Protein 1 Antibodies (167) and Golgi Membrane Protein 1 Kits (29) and many more products for this protein.
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Human GOLM1 Protein expressed in Human Cells - ABIN2005402
Kladney, Bulla, Guo, Mason, Tollefson, Simon, Koutoubi, Fimmel: GP73, a novel Golgi-localized protein upregulated by viral infection. in Gene 2000
Show all 4 references for ABIN2005402
Human GOLM1 Protein expressed in Escherichia coli (E. coli) - ABIN2005400
Kladney, Tollefson, Wold, Fimmel: Upregulation of the Golgi protein GP73 by adenovirus infection requires the E1A CtBP interaction domain. in Virology 2002
Show all 4 references for ABIN2005400
Results show that overexpression of GP73 in hepatocellular carcinoma cell (HCC (show FAM126A Proteins)) line retrieved the expression of epithelial-mesenchymal transition (EMT (show ITK Proteins)) markers, and promoted cell motility and invasion. High expression of GP73 was also found in HCC (show FAM126A Proteins) tissues with metastasis providing evidence for an important role of GP73 in HCC (show FAM126A Proteins) metastasis.
Serum GP73 had limited diagnostic value for HBV-related liver cancer. The combined use of serum GP73 and AFP (show AFP Proteins) levels improved the diagnostic efficacy.
GP73 enhances MMP-13 (show MMP13 Proteins) expression through cAMP responsive element binding protein (CREB (show CREB1 Proteins))-mediated transcription activation. Levels of GP73 and MMP-13 (show MMP13 Proteins) are increased and positively correlated in human HCC (show FAM126A Proteins) tissues. Augmented MMP-13 (show MMP13 Proteins) potentiates HCC (show FAM126A Proteins) cell metastasis.
the specific antibody could block the binding of A10-2 to GP73, and the specific binding of A10-2 to GP73 was also supported by the observation that several tumor cell lines exhibited variable expression level of GP73.
Transcatheter arterial chemoembolization significantly increased GP73 expression in patients with hepatocellular carcinoma.
GP73 and AFP (show AFP Proteins)-L3 are superior biomarkers to aid the diagnosis of small PHC (show SLC25A3 Proteins) with negative AFP (show AFP Proteins). The combined detection of biomarkers improved the diagnostic accuracy.
The results of this meta-analysis showed that serum GP73 + AFP (show AFP Proteins) exhibited significantly higher diagnostic accuracy for HCC (show FAM126A Proteins) than did serum GP73 or AFP (show AFP Proteins) alone.
Sublingual vein parameters and AFP (show AFP Proteins), AFP (show AFP Proteins)-L3, and GP73 serum gene expression facilitate early diagnosis of patients with hepatocellular carcinoma.
GOLPH2 may be a useful tissue biomarker for oesophageal disease.
a GP73 assay is not suitable for discriminating between primary malignant and benign tumors of the liver.
GRASP55 (show GORASP2 Proteins) responds to inflammasome stimulation,controls autophagy initiation and important for secretion of IL-1b (show IL1B Proteins) and IL-18 (show IL18 Proteins)
In Atp7b (show ATP7B Proteins)(-/-) mice, GP73 mRNA was significantly elevated at 20-46 weeks of age, coincident with extensive hepatic inflammation and fibrosis.
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi transmembrane protein. It processes proteins synthesized in the rough endoplasmic reticulum and assists in the transport of protein cargo through the Golgi apparatus. The expression of this gene has been observed to be upregulated in response to viral infection. Alternatively spliced transcript variants encoding the same protein have been described for this gene.
golgi membrane protein 1
, golgi phosphoprotein 2
, Golgi membrane protein 1
, golgi membrane protein GP73
, golgi protein, 73-kD
, Golgi reassembly-stacking protein 2
, golgi reassembly-stacking protein of 55 kDa