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The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. Additionally we are shipping Golgi Membrane Protein 1 Kits (36) and Golgi Membrane Protein 1 Proteins (36) and many more products for this protein.
Showing 10 out of 168 products:
Human Polyclonal GOLM1 Primary Antibody for IHC (p), IHC - ABIN268595
Riener, Stenner, Liewen, Soll, Breitenstein, Pestalozzi, Samaras, Probst-Hensch, Hellerbrand, Müllhaupt, Clavien, Bahra, Neuhaus, Wild, Fritzsche, Moch, Jochum, Kristiansen: Golgi phosphoprotein 2 (GOLPH2) expression in liver tumors and its value as a serum marker in hepatocellular carcinomas. in Hepatology (Baltimore, Md.) 2009
Show all 2 references for 268595
Cow (Bovine) Polyclonal GOLM1 Primary Antibody for WB - ABIN2782894
Bachert, Fimmel, Linstedt: Endosomal trafficking and proprotein convertase cleavage of cis Golgi protein GP73 produces marker for hepatocellular carcinoma. in Traffic (Copenhagen, Denmark) 2007
Human Polyclonal GOLM1 Primary Antibody for IHC, ELISA - ABIN184847
Kladney, Bulla, Guo, Mason, Tollefson, Simon, Koutoubi, Fimmel: GP73, a novel Golgi-localized protein upregulated by viral infection. in Gene 2000
Human Monoclonal GOLM1 Primary Antibody for ELISA, WB - ABIN526605
Braun, Menon, Nikolov, Kirsten, Petersen, Schilling, Schott, Gündisch, Fend, Becker, Perner: The HOPE fixation technique--a promising alternative to common prostate cancer biobanking approaches. in BMC cancer 2011
Both gain- and loss-of-function studies determine that GOLM1 acts as a key oncogene (show RAB1A Antibodies) by promoting HCC (show FAM126A Antibodies) growth and metastasis.
A cytokine QTL at the NAA35 (show MAK10 Antibodies)-GOLM1 locus markedly modulated interleukin (IL)-6 (show IL6 Antibodies) production in response to multiple pathogens and was associated with susceptibility to candidemia.
knock-down of GP73 down-regulates HCV infection and replication in Huh7-MAVSR cells and primary human hepatocytes
Studies indicate that golgi membrane protein 1 (GOLM1) may promote HCC (show FAM126A Antibodies) by regulation of epidermal growth factor receptor (EGFR (show EGFR Antibodies)) recycling, and suggest that therapeutic targeting of GOLM1 may be a potential strategy for combating hepatocellular carcinoma (HCC (show FAM126A Antibodies)) metastasis.
these studies revealed that GP73 promotes hepatitis C virus (HCV) secretion by directly mediating the interaction of ApoE (show APOE Antibodies) with HCV replication complex through binding with HCV NS5A.
Significantly higher serum levels of GP-73 and PIVKA-II were detected in the hepatocellular carcinoma patients than in controls.
The critical role of GP73 in hepatocellular carcinoma invasion, epithelial-mesenchymal transition and metastasis
Results show that overexpression of GP73 in hepatocellular carcinoma cell (HCC (show FAM126A Antibodies)) line retrieved the expression of epithelial-mesenchymal transition (EMT (show ITK Antibodies)) markers, and promoted cell motility and invasion. High expression of GP73 was also found in HCC (show FAM126A Antibodies) tissues with metastasis providing evidence for an important role of GP73 in HCC (show FAM126A Antibodies) metastasis.
Serum GP73 had limited diagnostic value for HBV-related liver cancer. The combined use of serum GP73 and AFP (show AFP Antibodies) levels improved the diagnostic efficacy.
GP73 enhances MMP-13 (show MMP13 Antibodies) expression through cAMP responsive element binding protein (CREB (show CREB1 Antibodies))-mediated transcription activation. Levels of GP73 and MMP-13 (show MMP13 Antibodies) are increased and positively correlated in human HCC (show FAM126A Antibodies) tissues. Augmented MMP-13 (show MMP13 Antibodies) potentiates HCC (show FAM126A Antibodies) cell metastasis.
Gorasp2 (show GORASP2 Antibodies)-/- mice suffered from spermatogenesis defects. Golgi morphology of spermatocytes was disturbed in Gorasp2 (show GORASP2 Antibodies)-/- mice. GRASP55 (show GORASP2 Antibodies) interacted via PDZ (show INADL Antibodies)-mediated interactions with JAMs.
GRASP55 (show GORASP2 Antibodies) responds to inflammasome stimulation,controls autophagy initiation and important for secretion of IL-1b (show IL1B Antibodies) and IL-18 (show IL18 Antibodies)
In Atp7b (show ATP7B Antibodies)(-/-) mice, GP73 mRNA was significantly elevated at 20-46 weeks of age, coincident with extensive hepatic inflammation and fibrosis.
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi transmembrane protein. It processes proteins synthesized in the rough endoplasmic reticulum and assists in the transport of protein cargo through the Golgi apparatus. The expression of this gene has been observed to be upregulated in response to viral infection. Alternatively spliced transcript variants encoding the same protein have been described for this gene.
golgi membrane protein 1
, golgi phosphoprotein 2
, Golgi membrane protein 1
, golgi membrane protein GP73
, golgi protein, 73-kD
, Golgi reassembly-stacking protein 2
, golgi reassembly-stacking protein of 55 kDa