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GOSR2 encodes a trafficking membrane protein which transports proteins among the medial- and trans-Golgi compartments. Additionally we are shipping GOSR2 Antibodies (30) and many more products for this protein.
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Human GOSR2 Protein expressed in Escherichia coli (E. coli) - ABIN1098790
Gmachl, Wimmer: Sequential involvement of p115, SNAREs, and Rab proteins in intra-Golgi protein transport. in The Journal of biological chemistry 2001
Show all 2 references for ABIN1098790
The SNAREs(Soluble N-ethylmaleimide-sensitive factor (show NSF Proteins) attachment protein receptors), that regulate both the biogenesis and secretion of multiple lysosome-related organelles(LROs).
Based on the presented phenotype, we would advise movement disorder specialists to consider mutation analysis of GOSR2 in patients with Ramsay Hunt syndrome, especially when they also have areflexia.
A haplotype of the GOSR2 gene is associated with myocardial infarction in Japanese men
Golgi vesicles, presumably with COPI, serve to inhibit intra-Golgi transport by the extraction of GS27 and GS28 (show GOSR1 Proteins) from the Golgi cisternae, which blocks the formation of inter-cisternal connections
Single nucleotide polymorphisms in the GOSR2 gene are associated with essential hypertension in Japanese men.
GOSR2 gene mutation is associated with progressive myoclonus epilepsy cases, all of whom came from countries bounding the North Sea (show Slc25a1 Proteins), extending to the coastal region of Northern Norway.
A homozygous mutation in GOSR2 (c.430G>T, p.Gly144Trp), was identified in five apparently unrelated families with a clinically distinct progressive myoclonic epilepsy syndrome.
These studies suggest that membrin recruits Arf-1 to the early Golgi and reveal distinct kinetic cycles for Arf-1 at early and late Golgi determined by different sets of Arf regulators and effectors.
We found evidence that a SNP in GOSR2 is modestly associated with hypertension in whites from the ARIC study and the WGHS.
This gene encodes a trafficking membrane protein which transports proteins among the medial- and trans-Golgi compartments. Due to its chromosomal location and trafficking function, this gene may be involved in familial essential hypertension. Three transcript variants encoding three different isoforms have been found for this gene.
Golgi SNAP receptor complex member 2
, golgi SNAP receptor complex member 2
, 27 kDa Golgi SNARE protein
, golgi SNARE