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Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 Proteins (GGA2)

GGA2 encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. Additionally we are shipping Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 Antibodies (39) and Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GGA2 74105 Q6P5E6
Rat GGA2 GGA2 293455  
GGA2 23062 Q9UJY4
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Top Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

GGA2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 (GGA2) Interaction Partners

Mouse (Murine) Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 (GGA2) interaction partners

  1. GGA2 binds to the internal DXXLL motif of the LRP9 (show LRP10 Proteins)

Human Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 (GGA2) interaction partners

  1. These data indicate that clathrin is required for the function of AP-1 (show FOSB Proteins)- and GGA-coated carriers at the trans-Golgi network but may be dispensable for outward traffic en route to the plasma membrane.

  2. GGA2 mediates a vital function that cannot be compensated for by GGA1and/or GGA3 (show GGA3 Proteins).

  3. endocytosis and intracellular transport of memapsin 2 (show BACE Proteins), mediated by its cytosolic domain, may involve the binding of GGA1 (show GGA1 Proteins) and GGA2

  4. Results demonstrate that cargo proteins contribute to the recruitment of GGA2 onto membranes and to the formation of GGA-positive clathrin-coated vesicles.

  5. p56 (show IFIT1 Proteins) tightly cooperates with the GGAs in the sorting of cathepsin D (show CTSD Proteins) to lysosomes, probably by enabling the movement of GGA-containing transport carriers.

  6. GGA2 is recruited to the trans-Golgi network independently of the other Golgi-localized, gamma-ear-containing, ARF-binding proteins and is required for the efficient sorting of lysosomal enzymes

  7. GGA overexpression causes various sorting defects as measured by recycling of CD-MPR, internalization of transferrin receptor, and the subcellular localization of proteins like Tsg101, ubiquitin, and Hrs.

Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 (GGA2) Protein Profile

Protein Summary

This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly.

Gene names and symbols associated with GGA2

  • golgi associated, gamma adaptin ear containing, ARF binding protein 2 (Gga2)
  • golgi-associated, gamma adaptin ear containing, ARF binding protein 2 (GGA2)
  • 1200007E24Rik protein
  • mKIAA1080 protein
  • VEAR protein

Protein level used designations for GGA2

ADP-ribosylation factor-binding protein GGA2 , gamma-adaptin-related protein 2 , golgi-localized, gamma ear-containing, ARF-binding protein 2 , VHS domain and ear domain of gamma-adaptin , VHS domain and ear domain-containing protein , golgi associated, gamma adaptin ear containing, ARF binding protein 2

GENE ID SPECIES
74105 Mus musculus
293455 Rattus norvegicus
23062 Homo sapiens
608555 Canis lupus familiaris
100524333 Sus scrofa
517031 Bos taurus
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