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Grainyhead-Like 3 (Drosophila) Proteins (GRHL3)

GRHL3 encodes a member of the grainyhead family of transcription factors. Additionally we are shipping GRHL3 Antibodies (39) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GRHL3 57822 Q8TE85
GRHL3 230824 Q5FWH3
Rat GRHL3 GRHL3 298555  
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Top GRHL3 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

GRHL3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Grainyhead-Like 3 (Drosophila) (GRHL3) Interaction Partners

Human Grainyhead-Like 3 (Drosophila) (GRHL3) interaction partners

  1. We discovered a genome-wide significant association with a missense variant in GRHL3 and replicated the result in an independent sample of case and control subjects. In both samples, rs41268753 conferred increased risk for cleft palate.

  2. We identified both rare dominant mutations and a common risk variant in the coding region of GRHL3 as causative in individuals with nonsyndromic cleft palate only.

  3. GRHL1 (show GRHL1 Proteins), GRHL2 (show GRHL2 Proteins), and GRHL3 have roles in cellular proliferation, differentiation, adhesion, and polarity and may promote cancer or be tumor suppressors [review]

  4. We defined a novel molecular signature in mammalian HNSCC, suggesting new treatment strategies targeting the GRHL3/GSK3B/c-MYC (show MYC Proteins) proto-oncogenic network.

  5. our results indicate predominant GRHL3 expression in breast cancers

  6. Our data demonstrated that mutations in two genes, IRF6 (show IRF6 Proteins) and GRHL3, can lead to nearly identical phenotypes of orofacial cleft.

  7. The splice variant-derived isoforms SOM1 and SOM3 induce opposing effects in primary human endothelial cells and in a whole animal model, most likely through the induction of different target genes.

  8. decreased Grhl3 expression contributes to tumor progression and upregulation of the oncomir miR (show MLXIP Proteins)-21 in squamous cell carcinoma of the skin.

  9. In human keratinocytes, IRF6 (show IRF6 Proteins) bound conserved elements near the GRHL3 promoter, with one of these elements having enhancer activity.

  10. we define a previously unknown role for the transcription factor GRHL3 in the recruitment of a trxG complex to promoters of genes, leading to increased H3K4 methylation and gene expression

Mouse (Murine) Grainyhead-Like 3 (Drosophila) (GRHL3) interaction partners

  1. Upregulation of miR21 and repression of Grhl3 by leptin (show LEP Proteins) mediates sinusoidal endothelial injury in experimental nonalcoholic steatohepatitis.

  2. This study identifies a GRHL3-regulated epidermal barrier repair pathway that suppresses disease initiation and helps resolve existing lesions in immune-mediated epidermal hyperplasia.

  3. decreased Grhl3 expression contributes to tumor progression and upregulation of the oncomir miR (show MLXIP Proteins)-21 in squamous cell carcinoma of the skin.

  4. The developmental transcription factor Grhl3 is a potent tumor suppressor of squamous cell carcinoma in mice.

  5. Both GRHL2 (show GRHL2 Proteins) and GRHL3 bind to and regulate expression of the wound repair gene Rho GEF (show ARHGEF2 Proteins) 19, but regulation of the barrier forming gene, Transglutaminase 1 (TGase1 (show TGM1 Proteins)), is unique to GRHL3.

  6. maps to Chromosome 4, 135 Mb (66 cM) from the centromere, probably not Idb3 (show ID3 Proteins), Wnt4 (show WNT4 Proteins), Cdc42 (show CDC42 Proteins), perlecan (show HSPG2 Proteins) or Grhl-3

  7. Loss of Grhl3 alone defines a distinct lower spinal closure defect, also with defective dorso-lateral hinge points formation

  8. folate deficiency caused a similar-sized, statistically significant increase in the frequency of exencephaly among both curly tail (Grhl3 mutant) embryos and background-matched embryos that are wild type for Grhl3.

  9. formation and maintenance of the epidermal barrier in mice are dependent on a mammalian homolog of grainy head, Grainy head-like 3[Grhl3]

  10. Unique role of Grhl3 in neurulation and epidermal morphogenesis.

GRHL3 Protein Profile

Protein Summary

This gene encodes a member of the grainyhead family of transcription factors. The encoded protein may function as a transcription factor during development, and has been shown to stimulate migration of endothelial cells. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Gene names and symbols associated with GRHL3

  • grainyhead-like 3 (Drosophila) (GRHL3)
  • grainyhead-like 3 (Drosophila) (Grhl3)
  • AI561912 protein
  • ct protein
  • Get1 protein
  • GRHL3 protein
  • Som protein
  • Tfcp2l4 protein

Protein level used designations for GRHL3

grainyhead-like 3 (Drosophila) , sister-of-mammalian grainyhead protein , grainyhead-like protein 3 homolog , sister of mammalian grainyhead , sister-of-mammalian grainyhead , transcription factor CP2-like 4 , transcription factor hSOM1 , grainy head-like 3

GENE ID SPECIES
419695 Gallus gallus
456630 Pan troglodytes
531906 Bos taurus
100057567 Equus caballus
57822 Homo sapiens
230824 Mus musculus
298555 Rattus norvegicus
487371 Canis lupus familiaris
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