Grainyhead-Like 3 (Drosophila) (GRHL3) ELISA Kits

GRHL3 encodes a member of the grainyhead family of transcription factors. Additionally we are shipping GRHL3 Antibodies (43) and GRHL3 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human GRHL3 GRHL3 57822 Q8TE85
Anti-Mouse GRHL3 GRHL3 230824 Q5FWH3
Anti-Rat GRHL3 GRHL3 298555  
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More ELISA Kits for GRHL3 Interaction Partners

Human Grainyhead-Like 3 (Drosophila) (GRHL3) interaction partners

  1. No association found between two GRHL3 SNPs (rs2486668 and rs545809) and non-syndromic orofacial clefts in the Han Chinese cohort.

  2. ey epidermal differentiation transcription factor genes, including GRHL3, are located within super-enhancers, and many of these transcription factors in turn bind to and regulate super-enhancers.

  3. GRHL3 expression may be useful as a prognostic factor.

  4. Study genotyped 10 tag SNPs covering GRHL3 and performed association analysis with nonsyndromic cleft lip with or without cleft palate in 504 cases and 455 healthy controls; preliminary results identified rs10903078, rs4638975, and a haplotype rs10903078-rs6659209 of GRHL3 that exceeded the significance threshold (p<0.05), though none survived Bonferroni correction for multiple comparisons.

  5. findings define a major role for Grhl3 in the induction of migration and invasion by the downregulation of E-cadherin (show CDH1 ELISA Kits) in cancer cells

  6. We discovered a genome-wide significant association with a missense variant in GRHL3 and replicated the result in an independent sample of case and control subjects. In both samples, rs41268753 conferred increased risk for cleft palate.

  7. We identified both rare dominant mutations and a common risk variant in the coding region of GRHL3 as causative in individuals with nonsyndromic cleft palate only.

  8. GRHL1 (show GRHL1 ELISA Kits), GRHL2 (show GRHL2 ELISA Kits), and GRHL3 have roles in cellular proliferation, differentiation, adhesion, and polarity and may promote cancer or be tumor suppressors [review]

  9. We defined a novel molecular signature in mammalian HNSCC, suggesting new treatment strategies targeting the GRHL3/GSK3B (show GSK3b ELISA Kits)/c-MYC (show MYC ELISA Kits) proto-oncogenic network.

  10. our results indicate predominant GRHL3 expression in breast cancers

Mouse (Murine) Grainyhead-Like 3 (Drosophila) (GRHL3) interaction partners

  1. Based on the results, it proposes that developmental stage-specific Grhl3 plays a significant role in circumvallate papilla (CVP) morphogenesis not by just disruption of epithelial integrity but by regulating epithelial cell proliferation, apoptosis, and migration via Shh (show SHH ELISA Kits), Wnt (show WNT2 ELISA Kits), and apoptosis signaling during mouse embryogenesis.

  2. Upregulation of miR21 and repression of Grhl3 by leptin (show LEP ELISA Kits) mediates sinusoidal endothelial injury in experimental nonalcoholic steatohepatitis.

  3. This study identifies a GRHL3-regulated epidermal barrier repair pathway that suppresses disease initiation and helps resolve existing lesions in immune-mediated epidermal hyperplasia.

  4. decreased Grhl3 expression contributes to tumor progression and upregulation of the oncomir miR (show MLXIP ELISA Kits)-21 in squamous cell carcinoma of the skin.

  5. The developmental transcription factor Grhl3 is a potent tumor suppressor of squamous cell carcinoma in mice.

  6. Both GRHL2 (show GRHL2 ELISA Kits) and GRHL3 bind to and regulate expression of the wound repair gene Rho GEF (show ARHGEF2 ELISA Kits) 19, but regulation of the barrier forming gene, Transglutaminase 1 (TGase1 (show TGM1 ELISA Kits)), is unique to GRHL3.

  7. maps to Chromosome 4, 135 Mb (66 cM) from the centromere, probably not Idb3 (show ID3 ELISA Kits), Wnt4 (show WNT4 ELISA Kits), Cdc42 (show CDC42 ELISA Kits), perlecan (show HSPG2 ELISA Kits) or Grhl-3

  8. Loss of Grhl3 alone defines a distinct lower spinal closure defect, also with defective dorso-lateral hinge points formation

  9. folate deficiency caused a similar-sized, statistically significant increase in the frequency of exencephaly among both curly tail (Grhl3 mutant) embryos and background-matched embryos that are wild type for Grhl3.

  10. formation and maintenance of the epidermal barrier in mice are dependent on a mammalian homolog of grainy head, Grainy head-like 3[Grhl3]

GRHL3 Antigen Profile

Antigen Summary

This gene encodes a member of the grainyhead family of transcription factors. The encoded protein may function as a transcription factor during development, and has been shown to stimulate migration of endothelial cells. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Gene names and symbols associated with GRHL3

  • grainyhead-like 3 (Drosophila) (GRHL3) antibody
  • grainyhead-like 3 (Drosophila) (Grhl3) antibody
  • AI561912 antibody
  • ct antibody
  • Get1 antibody
  • GRHL3 antibody
  • Som antibody
  • Tfcp2l4 antibody

Protein level used designations for GRHL3

grainyhead-like 3 (Drosophila) , sister-of-mammalian grainyhead protein , grainyhead-like protein 3 homolog , sister of mammalian grainyhead , sister-of-mammalian grainyhead , transcription factor CP2-like 4 , transcription factor hSOM1 , grainy head-like 3

GENE ID SPECIES
419695 Gallus gallus
456630 Pan troglodytes
531906 Bos taurus
100057567 Equus caballus
57822 Homo sapiens
230824 Mus musculus
298555 Rattus norvegicus
487371 Canis lupus familiaris
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