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Granulin (GRN) ELISA Kits

Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. Additionally we are shipping Granulin Antibodies (138) and Granulin Proteins (38) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GRN 2896 P28799
GRN 29143 P23785
GRN 14824  
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Top Granulin ELISA Kits at antibodies-online.com

Showing 10 out of 106 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 50pg/mL 1.56-100 ng/mL Human Progranulin PicoKine ELISA Kit standard curve 96 Tests Log in to see 4 to 6 Days
$369.00
Details
Mouse 10pg/mL 0.78-50 ng/mL Mouse Progranulin PicoKine ELISA Kit standard curve 96 Tests Log in to see 4 to 6 Days
$369.00
Details
Rat 0.47 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$800.00
Details
Human 0.44 ng/mL 0.14-100 ng/mL   96 Tests Log in to see 9 to 11 Days
$884.21
Details
Mouse 0.42 ng/mL 0.14-100 ng/mL   96 Tests Log in to see 9 to 11 Days
$909.47
Details
Rat 0.48 ng/mL 0.14-100 ng/mL   96 Tests Log in to see 9 to 11 Days
$960.00
Details
Pig
  96 Tests Log in to see 8 to 9 Days
$770.00
Details
Chicken
  96 Tests Log in to see 8 to 9 Days
$770.00
Details
Monkey
  96 Tests Log in to see 8 to 9 Days
$770.00
Details
Guinea Pig
  96 Tests Log in to see 8 to 9 Days
$770.00
Details

Top referenced Granulin ELISA Kits

  1. Human Granulin ELISA Kit for Sandwich ELISA - ABIN1672874 : Ahmed, Sheng, Xu, Lin, Innes, Gass, Yu, Wuertzer, Hou, Chiba, Yamanouchi, Leissring, Petrucelli, Nishihara, Hutton, McGowan, Dickson, Lewis: Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging. in The American journal of pathology 2010 (PubMed)
    Show all 2 references for ABIN1672874

  2. Mouse (Murine) Granulin ELISA Kit for Sandwich ELISA - ABIN1889363 : Kelley, Haidar, Boeve, Baker, Shiung, Knopman, Rademakers, Hutton, Adamson, Kuntz, Dickson, Parisi, Smith, Petersen: Alzheimer disease-like phenotype associated with the c.154delA mutation in progranulin. in Archives of neurology 2010 (PubMed)
    Show all 2 references for ABIN1889363

More ELISA Kits for Granulin Interaction Partners

Zebrafish Granulin (GRN) interaction partners

  1. the Grna and Grnb single and double knock out zebrafish lack any obvious morphological, pathological and biochemical phenotypes

  2. GrnA positively modulates hepatic MET expression both in vivo and in vitro.

Human Granulin (GRN) interaction partners

  1. In contrast with TBK1 (show TBK1 ELISA Kits) carriers, Belgian GRN carriers were more often diagnosed with the language variant than the behavioral variant in frontotemporal dementia patients.

  2. that progranulin could promote invasiveness of epithelial ovarian cancer cells through an epithelial mesenchymal transition program directly

  3. The study demonstrates increased PGRN expression at local sites of inflammation and association between PGRN levels, disease activity, and functional impairment in patients with Rheumatoid Arthritis.

  4. Data show that exclusive occurrence of pSer81 progranulin (PGRN) isoform in PGRN-antibody-positive patients.

  5. Progranulin overproduction due to Fli-1 (show FLI1 ELISA Kits) deficiency may contribute to the constitutive activation of SSc (show CYP11A1 ELISA Kits) dermal fibroblasts by antagonizing the antifibrotic effect of TNF (show TNF ELISA Kits).

  6. Drebrin (show DBN1 ELISA Kits) is critical for progranulin-dependent activation of the Akt (show AKT1 ELISA Kits) and MAPK (show MAPK1 ELISA Kits) pathways and modulates motility, invasion and anchorage-independent growth in bladder neoplasms.

  7. PGRN may play a critical role in homeostasis of IVD (show IVD ELISA Kits), and may serve as a potential molecular target for prevention and treatment of disc degenerative diseases.

  8. The clinical phenotype in GRN carriers is often Primary progressive aphasia or Corticobasal syndrome, with 25% showing psychotic symptoms.

  9. Serum PGRN is associated with disease activity and prognosis of DM with ILD. PGRN may play a role in the pathogenesis of DM and could be a useful biomarker.

  10. investigated the association between progranulin polymorphism rs5848 and risk of the neurodegenerative disease; data indicate rs5848 is associated with risk of Alzheimer's and Parkinson's disease [meta-analysis]

Mouse (Murine) Granulin (GRN) interaction partners

  1. Results suggest that PGRN is involved in the development and/or maturation of neuronal networks comprising Purkinje cells in the cerebellum, which may be a prerequisite to normal motor function

  2. PGRN is a key regulator of insulin (show INS ELISA Kits) resistance and PGRN may mediate its effects, at least in part, by inducing ER stress via the PERK (show EIF2AK3 ELISA Kits)-eIF2alpha (show EIF2A ELISA Kits) dependent pathway

  3. Progranulin overproduction due to Fli-1 (show FLI1 ELISA Kits) deficiency may contribute to the constitutive activation of SSc (show CYP11A1 ELISA Kits) dermal fibroblasts by antagonizing the antifibrotic effect of TNF (show TNF ELISA Kits).

  4. PGRN may play a critical role in homeostasis of IVD (show IVD ELISA Kits), and may serve as a potential molecular target for prevention and treatment of disc degenerative diseases.

  5. These data suggest that targeting activation of the alpha7 nAChR (show CHRNA7 ELISA Kits) pathway may be beneficial in decreasing neuroinflammation and reversing some of the behavioral deficits observed in progranulin-deficient frontotemporal dementia.

  6. Prosaposin (show PSAP ELISA Kits) facilitates sortilin (show SORT1 ELISA Kits)-independent lysosomal trafficking of progranulin.

  7. In conclusion, PGRN may be a promising treatment target for both atherosclerosis and inflammation-related osteoporosis.

  8. PGRN protects against colitis progression in mice in an IL-10 (show IL10 ELISA Kits) and TNFR2 (show TNFRSF1B ELISA Kits) dependent manner.

  9. progranulin may be a novel therapeutic target that provides vascular protection, anti-neuroinflammation, and neuroprotection

  10. Results show that Grn-/- mice develop age-related retinal degeneration concurrent with accumulation of autofluorescent material in the retina

Guinea Pig Granulin (GRN) interaction partners

  1. ADAM15 (show ADAM15 ELISA Kits) and acrogranin are present on and associated with the surface of guinea pig spermatozoa; besides both proteins may play a role during sperm-egg binding.

Granulin (GRN) Antigen Profile

Antigen Summary

Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.

Gene names and symbols associated with Granulin (GRN) ELISA Kits

  • granulin (GRN) antibody
  • granulin a (grna) antibody
  • Granulins (grn) antibody
  • granulin (grn) antibody
  • granulin (granulin) antibody
  • granulin (ORF1 granulin) antibody
  • granulin (Grn) antibody
  • acrogranin antibody
  • CLN11 antibody
  • DKFZp459H066 antibody
  • epithelin antibody
  • GEP antibody
  • GP88 antibody
  • grn antibody
  • MGC53354 antibody
  • PCDGF antibody
  • PEPI antibody
  • PGRN antibody
  • wu:fb11g12 antibody
  • wu:fj18f05 antibody

Protein level used designations for Granulin (GRN) ELISA Kits

granulin , granulin-a , zfPGRN-A , Granulins , PC cell-derived growth factor , acrogranin , granulin-epithelin , granulins , proepithelin , progranulin , PCDGF , PEPI , acrogranulin

GENE ID SPECIES
454728 Pan troglodytes
100051035 Equus caballus
791524 Danio rerio
100195018 Salmo salar
380370 Xenopus laevis
1463344 Adoxophyes orana granulovirus
2776804 Agrotis segetum granulovirus
100173689 Pongo abelii
2896 Homo sapiens
29143 Rattus norvegicus
14824 Mus musculus
480501 Canis lupus familiaris
733645 Sus scrofa
767942 Bos taurus
100135533 Cavia porcellus
100349528 Oryctolagus cuniculus
101115470 Ovis aries
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