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Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. Additionally we are shipping GDF15 Kits (62) and GDF15 Proteins (35) and many more products for this protein.
Showing 10 out of 313 products:
Chimpanzee Polyclonal GDF15 Primary Antibody for EIA, WB - ABIN453966
Baek, Eling: Changes in gene expression contribute to cancer prevention by COX inhibitors. in Progress in lipid research 2006
Show all 2 references for ABIN453966
Chimpanzee Polyclonal GDF15 Primary Antibody for EIA, WB - ABIN453968
Lindmark, Zheng, Wiklund, Bensen, Bälter, Chang, Hedelin, Clark, Stattin, Meyers, Adami, Isaacs, Grönberg, Xu: H6D polymorphism in macrophage-inhibitory cytokine-1 gene associated with prostate cancer. in Journal of the National Cancer Institute 2004
Show all 2 references for ABIN453968
Human Polyclonal GDF15 Primary Antibody for ELISA, WB - ABIN185465
Wollmann, Goodman, Bhat-Nakshatri, Kishimoto, Goulet, Mehrotra, Morimiya, Badve, Nakshatri: The macrophage inhibitory cytokine integrates AKT/PKB and MAP kinase signaling pathways in breast cancer cells. in Carcinogenesis 2005
High MIC-1 (show C18orf8 Antibodies) expression is associated with weight loss and poor response to chemotherapy in esophageal squamous cell carcinoma.
Study describes for the first time the vital role of GDF15 both in tumorigenesis and in radioresistance of OSCC cells. With its anti-apoptotic effects, GDF15 possibly promotes tumor progression and might protect carcinoma cells against irradiation effects.
GDF15 might play an important role in cellular senescence through a ROS (show ROS1 Antibodies)-mediated p16 (show CDKN2A Antibodies) pathway and contribute to the pathogenesis of atherosclerosis via pro-senescent activity.
High level of GDF15 expression is associated with breast cancer.
To investigate a possible association between GDF-15 levels and DNA methylation (show HELLS Antibodies), we performed a genome-wide DNA methylation (show HELLS Antibodies) study of white blood cells . This study shows that GDF-15 levels are associated with differences in DNA methylation (show HELLS Antibodies) in blood cells, and a subset of the loci are also differentially methylated in participants with Myocadial Infarction
This is the first report showing that GDF-15 appears to be expressed in the vitreous, and that its expression is significantly higher in the presence of a vitreoretinal disorder in which there is an inflammatory component.
Missense GDF15 mutations are associated with oral squamous cell carcinoma.
Review/Meta-analysis: High plasma GDF-15 levels are associated with an increased risk of mortality and recurrent myocardial infarction in patients with acute coronary syndrome.
Data suggest that growth differentiation factor 15 (GDF15) may promote colorectal cancer metastasis through activating epithelial-mesenchymal transition (EMT (show ITK Antibodies)), and could be considered as a prognostic clinical marker for colorectal cancer (CRC (show CALR Antibodies)).
MIC1 (show C18orf8 Antibodies) may have a role in colorectal adenoma in women, especially multiple, large, and proximal adenomas
The results of this study indicated the importance of Gdf-15 in promoting survival of DAergic neurons and regulating the inflammatory response post 6-OHDA lesion.
endogenous Growth/differentiation factor-15 is beneficial for axon regeneration following sciatic nerve crush
repeated cisterna magna administration of human umbilical cord blood-derived mesenchymal stem cells enhanced endogenous adult hippocampal neurogenesis and synaptic activity through a paracrine factor of GDF-15
Levels of GDF-15 mRNA increased 2 h after induction of ventilator-induced lung injury in WT lungs. Non-hematopoietic cells are the main source of GDF-15. GDF-15 is required for platelet-leukocyte interactions during ventilator-induced lung injury.
hNAG-1 appears to be a novel therapeutic target in preventing and treating obesity and insulin (show INS Antibodies) resistance.
Counterbalance between MIC-1 and ATF3 (show ATF3 Antibodies) is critical for deciding the fate of enterocytes under the food chemical stress.
Growth differentiation factor 15, a marker of lung involvement in systemic sclerosis, is involved in fibrosis development but is not indispensable for fibrosis development.
Growth/differentiation factor 15 promotes EGFR (show EGFR Antibodies) signalling, and regulates proliferation and migration in the hippocampus of neonatal and young adult mice.
GDF-15 is therefore prominently upregulated in the retina after optic nerve crush but does not directly interfere with the magnitude and temporal progression of retinal ganglion cell death.
GDF15 protects the renal interstitium and tubular compartment in experimental type 1 and 2 diabetes without affecting glomerular damage
Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.
growth differentiation factor 15
, NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1
, NSAID-activated gene 1 protein
, NSAID-regulated gene 1 protein
, growth/differentiation factor 15
, macrophage inhibitory cytokine 1
, placental TGF-beta
, placental bone morphogenetic protein
, prostate differentiation factor
, macrophage inhibiting cytokine-1