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Growth Differentiation Factor 15 Proteins (GDF15)

Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. Additionally we are shipping GDF15 Antibodies (313) and GDF15 Kits (62) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GDF15 9518 Q99988
GDF15 23886 Q9Z0J7
GDF15 29455 Q9Z0J6
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Top GDF15 Proteins at antibodies-online.com

Showing 10 out of 35 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human Fc Tag 50 μg Log in to see 16 Days
$272.80
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 2 to 3 Days
$525.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$583.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$313.50
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$668.80
Details
HOST_Mammalian Cells Mouse His tag   50 μg Log in to see 5 Days
$548.63
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$862.40
Details

GDF15 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, , ,
Mouse (Murine) , ,

Rat (Rattus)

Top referenced GDF15 Proteins

  1. Human GDF15 Protein expressed in Human Cells - ABIN2003620 : Bauskin, Zhang, Fairlie, He, Russell, Moore, Brown, Stanley, Breit: The propeptide of macrophage inhibitory cytokine (MIC-1), a TGF-beta superfamily member, acts as a quality control determinant for correctly folded MIC-1. in The EMBO journal 2000 (PubMed)
    Show all 2 references for ABIN2003620

  2. Human GDF15 Protein expressed in Escherichia coli (E. coli) - ABIN666670 : Hsiao, Koniaris, Zimmers-Koniaris, Sebald, Huynh, Lee: Characterization of growth-differentiation factor 15, a transforming growth factor beta superfamily member induced following liver injury. in Molecular and cellular biology 2000 (PubMed)
    Show all 2 references for ABIN666670

  3. Human GDF15 Protein expressed in Escherichia coli (E. coli) - ABIN809751 : Matsukawa, Hirooka, Ito, Sunagawa: Inhibition of neuregulin-1/ErbB signaling in the rostral ventrolateral medulla leads to hypertension through reduced nitric oxide synthesis. in American journal of hypertension 2013 (PubMed)

More Proteins for Growth Differentiation Factor 15 (GDF15) Interaction Partners

Human Growth Differentiation Factor 15 (GDF15) interaction partners

  1. GDF-15 is a valuable predictor of cardiovascular death in a population of coronary artery disease patients after PCI (show SERPINA5 Proteins)

  2. High glucose and insulin (show INS Proteins) peaks up-regulate GDF15 transcription and release.

  3. Data suggest that increased GDF-15 levels were positively associated with coronary artery disease.

  4. High expression of GDF15 is associated with ovarian cancer.

  5. Role of GDF15 in Type 2 diabetes mellitus. [review]

  6. High MIC-1 (show C18orf8 Proteins) expression is associated with weight loss and poor response to chemotherapy in esophageal squamous cell carcinoma.

  7. Study describes for the first time the vital role of GDF15 both in tumorigenesis and in radioresistance of OSCC cells. With its anti-apoptotic effects, GDF15 possibly promotes tumor progression and might protect carcinoma cells against irradiation effects.

  8. GDF15 might play an important role in cellular senescence through a ROS-mediated p16 pathway and contribute to the pathogenesis of atherosclerosis via pro-senescent activity.

  9. High level of GDF15 expression is associated with breast cancer.

  10. To investigate a possible association between GDF-15 levels and DNA methylation (show HELLS Proteins), we performed a genome-wide DNA methylation (show HELLS Proteins) study of white blood cells . This study shows that GDF-15 levels are associated with differences in DNA methylation (show HELLS Proteins) in blood cells, and a subset of the loci are also differentially methylated in participants with Myocadial Infarction

Mouse (Murine) Growth Differentiation Factor 15 (GDF15) interaction partners

  1. The results of this study indicated the importance of Gdf-15 in promoting survival of DAergic neurons and regulating the inflammatory response post 6-OHDA lesion.

  2. endogenous Growth/differentiation factor-15 is beneficial for axon regeneration following sciatic nerve crush

  3. repeated cisterna magna administration of human umbilical cord blood-derived mesenchymal stem cells enhanced endogenous adult hippocampal neurogenesis and synaptic activity through a paracrine factor of GDF-15

  4. Levels of GDF-15 mRNA increased 2 h after induction of ventilator-induced lung injury in WT lungs. Non-hematopoietic cells are the main source of GDF-15. GDF-15 is required for platelet-leukocyte interactions during ventilator-induced lung injury.

  5. hNAG-1 appears to be a novel therapeutic target in preventing and treating obesity and insulin (show INS Proteins) resistance.

  6. Counterbalance between MIC-1 and ATF3 (show ATF3 Proteins) is critical for deciding the fate of enterocytes under the food chemical stress.

  7. Growth differentiation factor 15, a marker of lung involvement in systemic sclerosis, is involved in fibrosis development but is not indispensable for fibrosis development.

  8. Growth/differentiation factor 15 promotes EGFR (show EGFR Proteins) signalling, and regulates proliferation and migration in the hippocampus of neonatal and young adult mice.

  9. GDF-15 is therefore prominently upregulated in the retina after optic nerve crush but does not directly interfere with the magnitude and temporal progression of retinal ganglion cell death.

  10. GDF15 protects the renal interstitium and tubular compartment in experimental type 1 and 2 diabetes without affecting glomerular damage

GDF15 Protein Profile

Protein Summary

Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.

Gene names and symbols associated with GDF15

  • growth differentiation factor 15 (GDF15)
  • growth differentiation factor 15 (Gdf15)
  • GDF-15 protein
  • GDF15 protein
  • MIC-1 protein
  • MIC1 protein
  • NAG-1 protein
  • PDF protein
  • PLAB protein
  • PTGFB protein
  • SBF protein

Protein level used designations for GDF15

growth differentiation factor 15 , NRG-1 , NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1 , NSAID-activated gene 1 protein , NSAID-regulated gene 1 protein , PTGF-beta , growth/differentiation factor 15 , macrophage inhibitory cytokine 1 , placental TGF-beta , placental bone morphogenetic protein , prostate differentiation factor , GDF-15 , macrophage inhibiting cytokine-1

GENE ID SPECIES
719466 Macaca mulatta
9518 Homo sapiens
23886 Mus musculus
29455 Rattus norvegicus
468770 Pan troglodytes
100718010 Cavia porcellus
100379630 Sus scrofa
484822 Canis lupus familiaris
618677 Bos taurus
100913168 Ovis aries
Selected quality suppliers for GDF15 Proteins (GDF15)
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