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Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. Additionally we are shipping GDF15 Kits (72) and GDF15 Proteins (38) and many more products for this protein.
Showing 10 out of 276 products:
Chimpanzee Polyclonal GDF15 Primary Antibody for EIA, WB - ABIN453963
Baek, Eling: Changes in gene expression contribute to cancer prevention by COX inhibitors. in Progress in lipid research 2006
Show all 2 references for ABIN453963
Chimpanzee Polyclonal GDF15 Primary Antibody for EIA, WB - ABIN453967
Lindmark, Zheng, Wiklund, Bensen, Bälter, Chang, Hedelin, Clark, Stattin, Meyers, Adami, Isaacs, Grönberg, Xu: H6D polymorphism in macrophage-inhibitory cytokine-1 gene associated with prostate cancer. in Journal of the National Cancer Institute 2004
Show all 2 references for ABIN453967
Human Polyclonal GDF15 Primary Antibody for WB - ABIN374600
Wollmann, Goodman, Bhat-Nakshatri, Kishimoto, Goulet, Mehrotra, Morimiya, Badve, Nakshatri: The macrophage inhibitory cytokine integrates AKT/PKB and MAP kinase signaling pathways in breast cancer cells. in Carcinogenesis 2005
The results of this study, including a robust induction of GDF-15 expression by several external factors known to elevate IOP, and rGDF-15-induced increase in contractility, cell adhesion, and the levels of ECM (show MMRN1 Antibodies) proteins and alphaSMA (show ACTA2 Antibodies) in TM cells
GDF-15 captures distinct aspects of cardiovascular disease development, progression, and prognosis, which are not represented by clinical risk predictors and other biomarkers. The usefulness of GDF-15 to guide management decisions and discover new treatment targets should be further explored.
In stable Coronary Heart Disease, GDF-15 was independently associated with cardiovascular (CV), non-CV, and cancer mortality, as well as with MI and stroke. When also adjusting for other prognostic biomarkers, the associations to all fatal and nonfatal events were maintained except for MI. Information on GDF-15, therefore, might be helpful when assessing the risk of adverse outcomes in patients with stable CHD (show CHDH Antibodies).
Impaired glucose tolerance is associated with increased GDF-15 levels even in the absence of anemia
GDF15 is a potent mitohormetic signal that safeguards against the onset of obesity and insulin (show INS Antibodies) resistance.
NAG-1 expression was transcriptionally upregulated by CHOP (show DDIT3 Antibodies), which promoted chemokine (show CCL1 Antibodies) production through sustained NF-kappaB (show NFKB1 Antibodies) activation.
ChIP studies showed that the S100A4 (show S100A4 Antibodies) protein binds to the GDF15 promoter, implicating S100A4 (show S100A4 Antibodies) in GDF15 regulation at the transcriptional level.
Study compared the diagnostic utility of GDF-15 with FGF-21 (show FGF21 Antibodies) in an adult mitochondrial disease cohort. GDF-15 outperforms FGF-21 (show FGF21 Antibodies) as an indicator of mitochondrial diseases. GDF-15 is generally indicative of inherited mitochondrial disease regardless of clinical phenotype, whereas FGF-21 (show FGF21 Antibodies) seems to be more indicative of mitochondrial disease when muscle manifestations are present
MIC1/GDF15 may have a role in monitoring bone metastases
GDF15 contributes to fibroblast activation and may be a novel functional secreted molecule for diffuse gastric cancer progression
The aim of this study was to identify the role of endogenous Gdf-15 in the MPTP (show PTPN2 Antibodies) (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) mouse model of Parkinson's disease (PD) by comparing Gdf-15 (+/+) and Gdf-15 (-/-) mice.
The results of this study indicated the importance of Gdf-15 in promoting survival of DAergic neurons and regulating the inflammatory response post 6-OHDA lesion.
endogenous Growth/differentiation factor-15 is beneficial for axon regeneration following sciatic nerve crush
repeated cisterna magna administration of human umbilical cord blood-derived mesenchymal stem cells enhanced endogenous adult hippocampal neurogenesis and synaptic activity through a paracrine factor of GDF-15
Levels of GDF-15 mRNA increased 2 h after induction of ventilator-induced lung injury in WT lungs. Non-hematopoietic cells are the main source of GDF-15. GDF-15 is required for platelet-leukocyte interactions during ventilator-induced lung injury.
hNAG-1 appears to be a novel therapeutic target in preventing and treating obesity and insulin (show INS Antibodies) resistance.
Counterbalance between MIC-1 and ATF3 (show ATF3 Antibodies) is critical for deciding the fate of enterocytes under the food chemical stress.
Growth differentiation factor 15, a marker of lung involvement in systemic sclerosis, is involved in fibrosis development but is not indispensable for fibrosis development.
Growth/differentiation factor 15 promotes EGFR (show EGFR Antibodies) signalling, and regulates proliferation and migration in the hippocampus of neonatal and young adult mice.
Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.
growth differentiation factor 15
, NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1
, NSAID-activated gene 1 protein
, NSAID-regulated gene 1 protein
, growth/differentiation factor 15
, macrophage inhibitory cytokine 1
, placental TGF-beta
, placental bone morphogenetic protein
, prostate differentiation factor
, macrophage inhibiting cytokine-1