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anti-Growth Differentiation Factor 2 (GDF2) Antibodies

The protein encoded by GDF2 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. Additionally we are shipping GDF2 Kits (74) and GDF2 Proteins (21) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GDF2 2658 Q9UK05
GDF2 12165 Q9WV56
GDF2 290921  
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Top anti-GDF2 Antibodies at antibodies-online.com

Showing 10 out of 77 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-GDF2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-hGDF2 N-term Pab (ABIN388817) is used in Western blot to detect hGDF2 in mouse liver tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA   1 mL Log in to see 6 to 8 Days
$544.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Mouse Un-conjugated Func, Neut, ELISA, WB   100 μg Log in to see 8 to 10 Days
$727.83
Details
Human Rabbit Un-conjugated WB GDF2 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 11 to 13 Days
$365.20
Details
Mouse Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$376.20
Details

GDF2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GDF2 Antibodies

  1. Human Polyclonal GDF2 Primary Antibody for IHC (p), WB - ABIN388817 : Herrera, van Dinther, Ten Dijke, Inman: Autocrine bone morphogenetic protein-9 signals through activin receptor-like kinase-2/Smad1/Smad4 to promote ovarian cancer cell proliferation. in Cancer research 2009 (PubMed)
    Show all 5 references for ABIN388817

  2. Human Polyclonal GDF2 Primary Antibody for EIA, IHC (p) - ABIN357458 : Majumdar, Wang, Morris: BMP-2 and BMP-9 promotes chondrogenic differentiation of human multipotential mesenchymal cells and overcomes the inhibitory effect of IL-1. in Journal of cellular physiology 2001 (PubMed)
    Show all 3 references for ABIN357458

  3. Chicken Polyclonal GDF2 Primary Antibody for WB - ABIN2786157 : David, Mallet, Keramidas, Lamandé, Gasc, Dupuis-Girod, Plauchu, Feige, Bailly: Bone morphogenetic protein-9 is a circulating vascular quiescence factor. in Circulation research 2008 (PubMed)

More Antibodies against GDF2 Interaction Partners

Human Growth Differentiation Factor 2 (GDF2) interaction partners

  1. In ovarian and breast epithelial cells, epigenetic regulation of GDF2 suppresses anoikis.

  2. BMP9 also influenced the expression of PPARgamma (show PPARG Antibodies).

  3. Data suggest ALK1 (show ACVRL1 Antibodies) and ACVR2A (show ACVR2A Antibodies)/ACVR2B (show ACVR2B Antibodies), acting as BMP9 co-receptors, rearrange pro-domains of BMP9--pro-domain dimer complex leading to displacement of pro-domains after receptor binding, release of mature non-dimer BPM9, and activation of signaling.

  4. DLL4 (show DLL4 Antibodies)/Notch1 (show NOTCH1 Antibodies) and BMP9 interdependent signaling induces endothelial cell quiescence via P27KIP1 (show CDKN1B Antibodies)/thrombospondin pathway.

  5. BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine (show CCL1 Antibodies) Responses

  6. BMP-9 induces vascular smooth muscle cell osteogenic differentiation and calcification via ALK1 (show ACVRL1 Antibodies), Smad (show SMAD1 Antibodies) and ALP (show ALP Antibodies) dependent mechanisms.

  7. This review summarizes the indirect connection between BMP9 and liver fibrosis, with a focus on the BMP9 signaling pathway members ALK1 (show ACVRL1 Antibodies), endoglin (show ENG Antibodies), Id1 (show ID1 Antibodies), hepcidin (show HAMP Antibodies) and Snail (show SNAI1 Antibodies). [review]

  8. Data show that bone morphogenetic protein 9 (BMP9) can inhibit the migration and invasion of MDA-MB-231 breast cancer cells and promote osteogenesis and proliferation of HS-5 bone marrow-derived mesenchymal stem cells in the co-culture system.

  9. structural analysis of the bone morphogenetic protein 9 procomplex

  10. These findings suggest that BMP9 can inhibit the proliferation and metastasis of SK-BR-3 cells via inactivating ERK1/2 (show MAPK1/3 Antibodies) and PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) signaling pathways

Mouse (Murine) Growth Differentiation Factor 2 (GDF2) interaction partners

  1. We have established a producer line that stably expresses a high level of active BMP9 protein. Such producer line should be a valuable resource for generating biologically active BMP9 protein for studying BMP9 signaling

  2. Data show that microRNA miR (show MLXIP Antibodies)-21 was significantly upregulated by bone morphogenetic protein 9 (BMP9) during the osteogenesis the multilineage cells (MMCs) by suppressing Smad7 (show SMAD7 Antibodies) protein.

  3. Hh signaling is involved and plays a regulatory role in the osteogenic differentiation of MSCs induced by BMP9.

  4. data indicate that BMP9 and BMP13 (show GDF6 Antibodies) (BMP9 might be more effective) promoted the differentiation of C3H10T1/2 cells into cardiomyocyte-like cells

  5. BMP9/ALK1 (show ACVRL1 Antibodies) augmented vasculogenesis and angiogenesis, and thereby enhanced neovascularization. Thus, we suggest that BMP9/ALK1 (show ACVRL1 Antibodies) may improve the efficacy of EPC (show TCF21 Antibodies)-based therapies for treating ischemic diseases.

  6. result was supported by the identification of the regulation by BMP9 and BMP10 (show BMP10 Antibodies) of several genes known to be involved in this process

  7. BMP-9 induces vascular smooth muscle cell osteogenic differentiation and calcification via ALK1 (show ACVRL1 Antibodies), Smad (show SMAD1 Antibodies) and ALP (show CCL21A Antibodies) dependent mechanisms.

  8. These findings suggest that PTEN (show PTEN Antibodies) plays an important role in regulating BMP9 induced osteogenic differentiation in MPCs, which may be mediated by PTEN (show PTEN Antibodies)/PI3K/Akt (show AKT1 Antibodies) signaling to modulate the expression of COX-2 (show COX2 Antibodies).

  9. BMP9 may be explored as a novel and efficacious factor for odontogenic regeneration.

  10. IGF2 increased the protein levels of hippocampal BMP9, NGF (show NGFB Antibodies), BDNF (show BDNF Antibodies), NT3 (show NTF3 Antibodies) and IGF1 (show IGF1 Antibodies) and of doublecortin (show DCX Antibodies), a marker of neurogenesis.

GDF2 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons.

Gene names and symbols associated with GDF2

  • growth differentiation factor 2 (gdf2) antibody
  • growth differentiation factor 2 (GDF2) antibody
  • growth differentiation factor 2 (Gdf2) antibody
  • BMP-9 antibody
  • Bmp9 antibody
  • DSL1 antibody

Protein level used designations for GDF2

bone morphogenetic protein 9 , GDF-2 , growth/differentiation factor 2 , BMP-9 , DSL-1 , dorsalin-1

GENE ID SPECIES
563287 Danio rerio
2658 Homo sapiens
12165 Mus musculus
396412 Gallus gallus
540384 Bos taurus
290921 Rattus norvegicus
100351972 Oryctolagus cuniculus
100519741 Sus scrofa
611149 Canis lupus familiaris
101115426 Ovis aries
100723076 Cavia porcellus
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