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Growth Differentiation Factor 2 Proteins (GDF2)

The protein encoded by GDF2 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. Additionally we are shipping GDF2 Antibodies (76) and GDF2 Kits (74) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GDF2 2658 Q9UK05
GDF2 12165 Q9WV56
Rat GDF2 GDF2 290921  
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Top GDF2 Proteins at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_CHO Cells Human Un-conjugated 25 μg Log in to see 10 to 12 Days
$320.68
Details
HOST_CHO Cells Mouse Un-conjugated 25 μg Log in to see 10 to 12 Days
$320.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_CHO Cells Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$1,071.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$844.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$897.60
Details
HOST_CHO Cells Human Un-conjugated   0.002 mg Log in to see 2 to 3 Days
$178.75
Details
HOST_Human Human His tag   10 μg Log in to see 5 Days
$203.50
Details

GDF2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, ,
Mouse (Murine) ,

Top referenced GDF2 Proteins

  1. Human GDF2 Protein expressed in CHO Cells - ABIN2666776 : Bidart, Ricard, Levet, Samson, Mallet, David, Subileau, Tillet, Feige, Bailly: BMP9 is produced by hepatocytes and circulates mainly in an active mature form complexed to its prodomain. in Cellular and molecular life sciences : CMLS 2012 (PubMed)
    Show all 8 references for ABIN2666776

  2. Mouse (Murine) GDF2 Protein expressed in CHO Cells - ABIN2666778 : Herrera, Dooley, Breitkopf-Heinlein: Potential roles of bone morphogenetic protein (BMP)-9 in human liver diseases. in International journal of molecular sciences 2014 (PubMed)
    Show all 8 references for ABIN2666778

More Proteins for Growth Differentiation Factor 2 (GDF2) Interaction Partners

Human Growth Differentiation Factor 2 (GDF2) interaction partners

  1. In ovarian and breast epithelial cells, epigenetic regulation of GDF2 suppresses anoikis.

  2. BMP9 also influenced the expression of PPARgamma (show PPARG Proteins).

  3. Data suggest ALK1 (show ACVRL1 Proteins) and ACVR2A (show ACVR2A Proteins)/ACVR2B (show ACVR2B Proteins), acting as BMP9 co-receptors, rearrange pro-domains of BMP9--pro-domain dimer complex leading to displacement of pro-domains after receptor binding, release of mature non-dimer BPM9, and activation of signaling.

  4. DLL4 (show DLL4 Proteins)/Notch1 (show NOTCH1 Proteins) and BMP9 interdependent signaling induces endothelial cell quiescence via P27KIP1 (show CDKN1B Proteins)/thrombospondin pathway.

  5. BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine (show CCL1 Proteins) Responses

  6. BMP-9 induces vascular smooth muscle cell osteogenic differentiation and calcification via ALK1 (show ACVRL1 Proteins), Smad (show SMAD1 Proteins) and ALP (show ALP Proteins) dependent mechanisms.

  7. This review summarizes the indirect connection between BMP9 and liver fibrosis, with a focus on the BMP9 signaling pathway members ALK1 (show ACVRL1 Proteins), endoglin (show ENG Proteins), Id1 (show ID1 Proteins), hepcidin (show HAMP Proteins) and Snail (show SNAI1 Proteins). [review]

  8. Data show that bone morphogenetic protein 9 (BMP9) can inhibit the migration and invasion of MDA-MB-231 breast cancer cells and promote osteogenesis and proliferation of HS-5 bone marrow-derived mesenchymal stem cells in the co-culture system.

  9. structural analysis of the bone morphogenetic protein 9 procomplex

  10. These findings suggest that BMP9 can inhibit the proliferation and metastasis of SK-BR-3 cells via inactivating ERK1/2 and PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) signaling pathways

Mouse (Murine) Growth Differentiation Factor 2 (GDF2) interaction partners

  1. We have established a producer line that stably expresses a high level of active BMP9 protein. Such producer line should be a valuable resource for generating biologically active BMP9 protein for studying BMP9 signaling

  2. Data show that microRNA miR (show MLXIP Proteins)-21 was significantly upregulated by bone morphogenetic protein 9 (BMP9) during the osteogenesis the multilineage cells (MMCs) by suppressing Smad7 (show SMAD7 Proteins) protein.

  3. Hh signaling is involved and plays a regulatory role in the osteogenic differentiation of MSCs induced by BMP9.

  4. data indicate that BMP9 and BMP13 (show GDF6 Proteins) (BMP9 might be more effective) promoted the differentiation of C3H10T1/2 cells into cardiomyocyte-like cells

  5. BMP9/ALK1 (show ACVRL1 Proteins) augmented vasculogenesis and angiogenesis, and thereby enhanced neovascularization. Thus, we suggest that BMP9/ALK1 (show ACVRL1 Proteins) may improve the efficacy of EPC (show TCF21 Proteins)-based therapies for treating ischemic diseases.

  6. result was supported by the identification of the regulation by BMP9 and BMP10 (show BMP10 Proteins) of several genes known to be involved in this process

  7. BMP-9 induces vascular smooth muscle cell osteogenic differentiation and calcification via ALK1 (show ACVRL1 Proteins), Smad (show SMAD1 Proteins) and ALP (show CCL21A Proteins) dependent mechanisms.

  8. These findings suggest that PTEN plays an important role in regulating BMP9 induced osteogenic differentiation in MPCs, which may be mediated by PTEN/PI3K/Akt (show AKT1 Proteins) signaling to modulate the expression of COX-2.

  9. BMP9 may be explored as a novel and efficacious factor for odontogenic regeneration.

  10. IGF2 increased the protein levels of hippocampal BMP9, NGF (show NGFB Proteins), BDNF (show BDNF Proteins), NT3 (show NTF3 Proteins) and IGF1 (show IGF1 Proteins) and of doublecortin (show DCX Proteins), a marker of neurogenesis.

GDF2 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons.

Gene names and symbols associated with GDF2

  • growth differentiation factor 2 (gdf2)
  • growth differentiation factor 2 (GDF2)
  • growth differentiation factor 2 (Gdf2)
  • BMP-9 protein
  • Bmp9 protein
  • DSL1 protein

Protein level used designations for GDF2

bone morphogenetic protein 9 , GDF-2 , growth/differentiation factor 2 , BMP-9 , DSL-1 , dorsalin-1

GENE ID SPECIES
563287 Danio rerio
2658 Homo sapiens
12165 Mus musculus
396412 Gallus gallus
540384 Bos taurus
290921 Rattus norvegicus
100351972 Oryctolagus cuniculus
100519741 Sus scrofa
611149 Canis lupus familiaris
101115426 Ovis aries
100723076 Cavia porcellus
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