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Growth Differentiation Factor 3 Proteins (GDF3)

The protein encoded by GDF3 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. Additionally we are shipping GDF3 Antibodies (85) and GDF3 Kits (48) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GDF3 9573 Q9NR23
GDF3 14562 Q07104
GDF3 500311  
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Top GDF3 Proteins at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 2 to 3 Days
$651.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 10 to 12 Days
$233.72
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$792.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 7 to 9 Days
$328.21
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$844.80
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,218.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   0.005 mg Log in to see 2 to 3 Days
$178.75
Details

GDF3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)
,
Rat (Rattus)

Top referenced GDF3 Proteins

  1. Human GDF3 Protein expressed in Escherichia coli (E. coli) - ABIN2667419 : Chacón-Camacho, Camarillo-Blancarte, Pelaez-González, Mendiola, Zenteno: Klippel-Feil syndrome associated with situs inversus: description of a new case and exclusion of GDF1, GDF3 and GDF6 as causal genes. in European journal of medical genetics 2012 (PubMed)
    Show all 6 references for ABIN2667419

More Proteins for Growth Differentiation Factor 3 (GDF3) Interaction Partners

Human Growth Differentiation Factor 3 (GDF3) interaction partners

  1. The results expand the spectrum of mutations associated with CHDs and first suggest the potentially disease-related GDF3 gene variant in the pathogenesis of CHDs.

  2. first evidence that NANOG (show NANOG Proteins) is a transcriptional activator of the expression of the oncogenic growth factor GDF3 in embryonic carcinoma cells

  3. GDF3 expression level was significantly down-regulated in breast cancer tissues compared to the surrounding nontumorous tissues.

  4. the conditioned medium from CHO-GDF3 could reduce PC12 cell growth and induce cell differentiation

  5. Growth differentiation factor 3 is induced by bone morphogenetic protein 6 (BMP-6 (show BMP6 Proteins)) and BMP-7 (show BMP7 Proteins) and increases luteinizing hormone receptor (show LHCGR Proteins) messenger RNA expression in human granulosa cells.

  6. Mutation of GDF3 causes ocular and skeletal anomalies.

  7. Present data suggested that GDF3 might play important roles in the central nervous system (CNS), especially in cerebral cortex, hippocampus and cerebellum, and it shed new light on further research of GDF3 in the central nervous system.

  8. GDF3 regulates both of the two major characteristics of embryonic stem cells: the ability to maintain the undifferentiated state and the ability to differentiate into the full spectrum of cell types.

  9. GDF3 regulates adipose-tissue homeostasis and energy balance under nutrient overload in part by signaling through the ALK7 (show ACVR1C Proteins) receptor

  10. GDF3 is either a bi-functional TGF-beta ligand, or, more likely, that it is a BMP inhibitor that can artificially activate Nodal signaling under non-physiological conditions.

Mouse (Murine) Growth Differentiation Factor 3 (GDF3) interaction partners

  1. GDF3 has the ability to induce progression of CD24 (show CD24 Proteins)-inducible melanoma in mice.

  2. Mice transduced with GDF-3 displayed profound weight gain when fed with high fat diet. The phenotypes included greatly expanded adipose tissue mass, increased body adiposity, highly hypertrophic adipocytes, hepatic steatosis, and elevated plasma leptin (show LEP Proteins).

  3. GDF3 regulates both of the two major characteristics of embryonic stem cells: the ability to maintain the undifferentiated state and the ability to differentiate into the full spectrum of cell types.

  4. Gdf3 is expressed in the inner cell mass and epiblast, and null mutants frequently exhibit abnormal formation or positioning of the anterior visceral endoderm in pre-gastrulation development

  5. Results suggest that GDF1 (show GDF1 Proteins) and GDF3 together represent the functional mammalian homologs of Vg1.

  6. GDF3 regulates adipose-tissue homeostasis and energy balance under nutrient overload in part by signaling through the ALK7 (show ACVR1C Proteins) receptor

  7. GDF3 deficiency selectively affects white adipose through its influence on basal metabolic rates.

Xenopus laevis Growth Differentiation Factor 3 (GDF3) interaction partners

  1. Xnr1 (show NODAL Proteins) and derriere are coexpressed in the posterior paraxial mesoderm at neurula stage, and with Coco (show DAND5 Proteins) define a posttranscriptionally regulated signaling center in the chain leading to an increased TGF-beta (show TGFB1 Proteins) signal on the left side of the embryo.

GDF3 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues.

Gene names and symbols associated with GDF3

  • growth differentiation factor 3 (GDF3)
  • growth differentiation factor 3 (Gdf3)
  • growth differentiation factor 3 (LOC100346534)
  • growth differentiation factor 3 (gdf3)
  • growth/differentiation factor 3-like (LOC100510963)
  • C78318 protein
  • CVG1 protein
  • der protein
  • derriere protein
  • ecat9 protein
  • Gdf-3 protein
  • gdf3-a protein
  • KFS3 protein
  • MCOP7 protein
  • MCOPCB6 protein
  • RGD1564178 protein
  • vgr-2 protein
  • vgr2 protein

Protein level used designations for GDF3

GDF-3 , growth/differentiation factor 3 , VG-1-related protein 2 , growth factor CVg1 , derriA re , derriere (posterior determination, TGFb family member) , derriere (tgf-beta family member) , derriere protein , gdf-3

GENE ID SPECIES
9573 Homo sapiens
14562 Mus musculus
500311 Rattus norvegicus
100346534 Oryctolagus cuniculus
100733509 Cavia porcellus
477702 Canis lupus familiaris
786521 Bos taurus
396132 Gallus gallus
101103967 Ovis aries
394305 Xenopus laevis
100510963 Sus scrofa
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