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anti-Growth Differentiation Factor 6 (GDF6) Antibodies

GDF6 encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily of secreted signaling molecules. Additionally we are shipping Growth Differentiation Factor 6 Kits (37) and Growth Differentiation Factor 6 Proteins (19) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GDF6 392255 Q6KF10
GDF6 242316 P43028
GDF6 252834 Q6HA10
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Top anti-Growth Differentiation Factor 6 Antibodies at antibodies-online.com

Showing 10 out of 55 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of GDF6 antibody (C-term) (ABIN391699) in mouse kidney tissue lysates (35 µg/lane). GDF6 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with GDF6 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of Hela cells using BMP13 / GDF6 Antibody (N-term) Cat.-No AP51812PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue reacted with BMP13 / GDF6 Antibody (N-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of GDF6 in SK-N-SH lysate with AP30360PU-N GDF6 antibody at (A) 0.5 and (B) 1 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Mouse Rabbit Un-conjugated FACS, IHC (p), WB GDF6 Antibody (N-term) (ABIN655618) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western blot analysis using recombinat human BMP-13. Both monomer and dimer can be detected. 100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Mouse Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$396.00
Details
Mouse Rabbit Un-conjugated FACS, IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB   400 μL Log in to see 8 to 10 Days
$463.83
Details

GDF6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Growth Differentiation Factor 6 Antibodies

  1. Human Polyclonal GDF6 Primary Antibody for EIA, WB - ABIN499881 : Hanel, Hensey: Eye and neural defects associated with loss of GDF6. in BMC developmental biology 2006 (PubMed)
    Show all 4 references for ABIN499881

  2. Human Polyclonal GDF6 Primary Antibody for EIA, FACS - ABIN950666 : Gonzalez-Rodriguez, Pelcastre, Tovilla-Canales, Garcia-Ortiz, Amato-Almanza, Villanueva-Mendoza, Espinosa-Mattar, Zenteno: Mutational screening of CHX10, GDF6, OTX2, RAX and SOX2 genes in 50 unrelated microphthalmia-anophthalmia-coloboma (MAC) spectrum cases. in The British journal of ophthalmology 2010 (PubMed)
    Show all 3 references for ABIN950666

  3. Human Polyclonal GDF6 Primary Antibody for FACS, IHC (p) - ABIN391699 : Tassabehji, Fang, Hilton, McGaughran, Zhao, de Bock, Howard, Malass, Donnai, Diwan, Manson, Murrell, Clarke: Mutations in GDF6 are associated with vertebral segmentation defects in Klippel-Feil syndrome. in Human mutation 2008 (PubMed)

More Antibodies against Growth Differentiation Factor 6 Interaction Partners

Zebrafish Growth Differentiation Factor 6 (GDF6) interaction partners

  1. This work establishes a novel link between tbx2b and gdf6a in determining photoreceptor fates.

  2. gdf6a is a dorsal initiation signal acting from the extraocular non-neural ectoderm during optic vesicle evagination.

  3. The spectrum of disorders generated by morpholino inhibition and the more severe defects (microphthalmia and anophthalmia) observed at higher doses illustrate the key role of GDF6 in ocular development.

  4. These data establish the important role of growth differentiation factor 6 in ocular and vertebral development.

  5. Gdf6a initiates dorsal retinal patterning independent of Bmp4 (show BMP4 Antibodies), and regulates lens differentiation.

Human Growth Differentiation Factor 6 (GDF6) interaction partners

  1. As fetal age increased, the expression of growth differentiation factor 6 was decreased correspondingly with the progress of ossification in vertebral bodies and restricted to cartilaginous regions.

  2. BMP13 has a role in enhancing extracellular matrix accumulation and inducing cell migration in certain intervertebral disc cells

  3. GDF6 is overexpressed in Leri's pleonosteosis.

  4. There was a possible weak association between the rs6982567 near GDF6 and polypoidal choroidal vasculopathy in this replication study with an independent Han Chinese cohort.

  5. Deficiency of gdf6 results in photoreceptor degeneration, so demonstrating a connection between Gdf6 signaling and photoreceptor survival.

  6. a critical role of HTRA1 (show HTRA1 Antibodies) in the regulation of angiogenesis via TGF-beta (show TGFB1 Antibodies) signaling and identified GDF6 as a novel disease gene for AMD (show AMD1 Antibodies).

  7. studies show that even though tenogenic (BMP 12 (show GDF7 Antibodies) and BMP 13) and osteogenic (BMP2 (show BMP2 Antibodies)) BMPs bind the same receptors with high affinity they signal much differently and result in differential activation of osteogenic and tenogenic markers

  8. These data suggest a potential role for BMP-13 (the human homologue to GDF-6) in tendon matrix modeling and/or remodeling.

  9. The spectrum of disorders generated by morpholino inhibition and the more severe defects (microphthalmia and anophthalmia) observed at higher doses illustrate the key role of GDF6 in ocular development.

  10. Mutation screening of a large and clinically diverse Klippel-Feil syndrome (KFS) cohort has identified GDF6 missense mutations in both familial and sporadic KFS patients.

Mouse (Murine) Growth Differentiation Factor 6 (GDF6) interaction partners

  1. data indicate that BMP9 (show GDF2 Antibodies) and BMP13 (BMP9 (show GDF2 Antibodies) might be more effective) promoted the differentiation of C3H10T1/2 cells into cardiomyocyte-like cells

  2. Over-expression of Gdf6 induces commitment of pluripotent mesenchymal C3H10T1/2 cells to the adipocyte lineage.

  3. Gdf6 plays an inhibitory role to prevent the osteogenic differentiation of the coronal suture mesenchyme

  4. a critical role of HTRA1 (show HTRA1 Antibodies) in the regulation of angiogenesis via TGF-beta (show TGFB1 Antibodies) signaling and identified GDF6 as a novel disease gene for AMD (show AMD1 Antibodies).

  5. These data suggest a potential role for BMP-13 (the human homologue to GDF-6) in tendon matrix modeling and/or remodeling.

  6. role of single and double mutations in the mouse Gdf6 and Gdf5 (show GDF5 Antibodies) genes in multiple joint and skeletal patterning defects

  7. The sequences for complex, regulatory elements responsible for Gdf6 regulation during embryonic skeletal development have been identified.

  8. These data establish the important role of growth differentiation factor 6 in ocular and vertebral development.

Growth Differentiation Factor 6 (GDF6) Antigen Profile

Protein Summary

This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily of secreted signaling molecules. It is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), which is a congenital disorder of spinal segmentation.

Gene names and symbols associated with GDF6

  • growth differentiation factor 6 (GDF6) antibody
  • growth differentiation factor 6 (gdf6) antibody
  • growth differentiation factor 6a (gdf6a) antibody
  • growth differentiation factor 6 (Gdf6) antibody
  • growth differentiation factor 6 (LOC100355026) antibody
  • growth differentiation factor 7 (GDF7) antibody
  • BMP13 antibody
  • CDMP-2 antibody
  • CDMP2 antibody
  • gdf6 antibody
  • GDF6/7 antibody
  • gdf16 antibody
  • KFM antibody
  • KFS antibody
  • KFS1 antibody
  • KFSL antibody
  • LCA17 antibody
  • MCOP4 antibody
  • MCOPCB6 antibody
  • rdr antibody
  • sb:cb278 antibody
  • SCDO4 antibody
  • SGM1 antibody

Protein level used designations for GDF6

growth differentiation factor 6 , GDF-6-A , cb278 , darl , growth/differentiation factor 6-A , out , protein radar , radar , GDF-6 , Klip-Feil malformation , Klippel-Feil malformation , Klippel-Feil syndrome , growth/differentiation factor 16 , growth/differentiation factor 6 , growth differentiation factor 16 , cartilage-derived morphogenetic protein 2

GENE ID SPECIES
100059475 Equus caballus
548831 Xenopus (Silurana) tropicalis
566470 Danio rerio
392255 Homo sapiens
242316 Mus musculus
252834 Rattus norvegicus
100355026 Oryctolagus cuniculus
100731904 Cavia porcellus
407175 Bos taurus
100686579 Canis lupus familiaris
101108925 Ovis aries
428655 Gallus gallus
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