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anti-Growth Differentiation Factor 9 (GDF9) Antibodies

Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. Additionally we are shipping GDF9 Kits (42) and GDF9 Proteins (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GDF9 2661 O60383
GDF9 14566 Q07105
GDF9 59304  
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Top anti-GDF9 Antibodies at antibodies-online.com

Showing 10 out of 123 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB GDF9 Antibody (N-term) (ABIN656116) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-GDF9 N-term Pab (ABIN388822) is used in Western blot to detect GDF9 in HL60 cell lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma reacted with GDF9 Antibody (N-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of GDF9 Antibody (N-term) in K562 cell line lysates (35ug/lane).This demonstrates the GDF9 antibody detected the GDF9 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of GDF9 staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. AEC was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of GDF9 expression in HL60 (A) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated EIA, IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB Western blot analysis using recombinant human GDF-9. Lane 1, 50 ng Lane 2, 250 ng Lane 3, 1 ug 100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Skin (formalin-fixed, paraffin-embedded) stained with GDF9 antibody ABIN214650 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Lane 1: human colon carcinoma lysates Lane 2: mouse embryo lysates probed with Anti AVPR2 Polyclonal Antibody, Unconjugated (ABIN1386214) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 50kD. Observed band size: 50kD. 100 μL Log in to see 3 to 7 Days
$269.50
Details

GDF9 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-GDF9 Antibodies

  1. Human Polyclonal GDF9 Primary Antibody for EIA, IHC (p) - ABIN952487 : Bokobza, Ye, Kynaston, Jiang: GDF-9 promotes the growth of prostate cancer cells by protecting them from apoptosis. in Journal of cellular physiology 2010 (PubMed)
    Show all 3 references for ABIN952487

  2. Human Polyclonal GDF9 Primary Antibody for EIA, IHC (p) - ABIN357463 : Vitt, Mazerbourg, Klein, Hsueh: Bone morphogenetic protein receptor type II is a receptor for growth differentiation factor-9. in Biology of reproduction 2002 (PubMed)
    Show all 2 references for ABIN357463

  3. Human Polyclonal GDF9 Primary Antibody for IHC (p), WB - ABIN388822 : Hendarto, Prabowo, Moeloek, Soetjipto: Growth differentiation factor 9 concentration in the follicular fluid of infertile women with endometriosis. in Fertility and sterility 2010 (PubMed)
    Show all 2 references for ABIN388822

More Antibodies against GDF9 Interaction Partners

Zebrafish Growth Differentiation Factor 9 (GDF9) interaction partners

  1. GDF9 expression was highest in primary growth follicles and gradually decreased during follicular development. Lowest level was found in fully grown follicles. It was maintained through fertilization and early embryonic development until gastrulation.

Human Growth Differentiation Factor 9 (GDF9) interaction partners

  1. GDF9 c.169G>T (D57Y), c.546G>A (rs1049127), and BMP15 (show BMP15 Antibodies) rs79377927 (788_789insTCT) were associated with premature ovarian failure in the Chinese Hui population.

  2. results support a model of activation for human GDF9 dependent on cumulin formation through heterodimerization with BMP15 (show BMP15 Antibodies). Oocyte-secreted cumulin is likely to be a central regulator of fertility in mono-ovular mammals.

  3. GDF-9 and GDF-15 (show GDF15 Antibodies) levels may influence bone parameters in polycystic ovary syndrome

  4. GDF9 and BMP15 (show BMP15 Antibodies) expression is reduced in primordial, primary, and secondary follicles in ovarian tissues of PCOS patients.

  5. The arginine residue in the pre-helix loop of GDF9 homodimer may prevent the inhibition from its pro-domain or directly alter receptor binding, but this residue in GDF9 does not significantly affect the heterodimer activity.

  6. Eleven unique copy number changes are identified in a total of 11 patients, including a tandem duplication of 475 bp, containing part of the GDF9 gene promoter region.

  7. Data suggest up-regulation of mRNA for GDF9 and BMP15 (bone morphogenetic protein 15 (show BMP15 Antibodies)) in cumulus granulosa cells serves as biomarker for oocyte maturation, fertilization, embryo quality, and pregnancy in couples undergoing ICSI for male infertility.

  8. These results suggest that COCs cultured with recombinant GDF9 in oocyte maturation medium improve oocyte developmental competence and subsequent developmental competence of cloned embryo in cattle.

  9. Reduced expression of growth and differentiation factor-9 is associated with aggressive behaviour of clear-cell renal cell carcinoma (show MOK Antibodies).

  10. Oocyte-derived GDF9 does not alter gap junction intercellular communication activity between human granulosa cells.

Mouse (Murine) Growth Differentiation Factor 9 (GDF9) interaction partners

  1. In organogenesis of the ovary, production of Dhh (show DHH Antibodies)/Ihh (show IHH Antibodies) in granulosa cells requires growth differentiation factor 9 from the oocyte.

  2. results support a model of activation for human GDF9 dependent on cumulin formation through heterodimerization with BMP15 (show BMP15 Antibodies). Oocyte-secreted cumulin is likely to be a central regulator of fertility in mono-ovular mammals.

  3. The arginine residue in the pre-helix loop of GDF9 homodimer may prevent the inhibition from its pro-domain or directly alter receptor binding, but this residue in GDF9 does not significantly affect the heterodimer activity during heterodimer formation.

  4. modified oocyte glycoproteins alter GDF9:BMP15 (show BMP15 Antibodies) expression modifying follicle development resulting in the generation of more follicles

  5. A novel role for GDF9 in causing reproductive defects and suppressing tumor initiation in the Inha (show INHA Antibodies)(-/-) mouse model.

  6. Embryo vitrification has no effect on ovarian morphology or expression of GDF9.

  7. The results show that chronic unpredictable stress suppresses GDF9 expression.

  8. show that purified mature regions of GDF9 and BMP15 (show BMP15 Antibodies) synergistically interact in a specific manner which is not dependent on the presence of a pro-region.

  9. GDF9 may contribute to the variation observed in follicular development, ovulation rate, and fecundity between mammals

  10. Data indicate that GDF-9 is absent in follicles of obese anovulatory/PCOS ovaries; upon treatment by heterotopic transplantation of gonadal adipose tissue from lean mice, expression of GDF-9 and ovulation appear to resume.

Pig (Porcine) Growth Differentiation Factor 9 (GDF9) interaction partners

  1. These results show that GDF9 and BMP15 (show BMP15 Antibodies) participate in cumulus expansion and that they stimulate MPF (show MSLN Antibodies) and MAPK (show MAPK1 Antibodies) activities in porcine oocytes during in vitro maturation.

  2. Report temporal regulation of GDF9 mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig.

  3. injection of porcine GDF-9 gene resulted in an increase in the number of primary, secondary and tertiary ovarian follicles

  4. Porcine GDF9 gene was found to be highly expressed in immature oocytes and declined slowly during the oocyte maturation process

  5. GDF9 may be not associated with pig litter size in extensive populations as per the studies of allele distributions of the four polymorphisms and pilot association in four breeds.

Cow (Bovine) Growth Differentiation Factor 9 (GDF9) interaction partners

  1. Immunization against GDF9 and BMP15 (show BMP15 Antibodies), alone or together, altered follicular development and ovulation rate in cattle.

  2. GDF9 expression in the oocytes of calf ovaries was significantly higher than in those of the adult ovaries

  3. GDF-9 mediates its effect through the pathway commonly activated by TGF beta (show TGFB1 Antibodies) and activin (show Actbeta Antibodies), but not that activated by many BMPs

  4. Maternal GDF9 transcripts persisted during oocyte in vitro maturation and fertilization and in preimplantation embryo until the five- to eight-cell or morula stage, but transcription was not reactivated at the time of embryonic genome activation.

  5. Oocyte- and granulosa cell-derived GDF9 may simultaneously promote theca cell proliferation and prevent premature differentiation of the theca interna during early follicle development.

Goat Growth Differentiation Factor 9 (GDF9) interaction partners

  1. Expression of BMP15 (show BMP15 Antibodies) (p < 0.01) and GDF9 (p < 0.05) mRNAs was more abundant in the small than the large antral follicles of Black Bengal goat.

  2. GNRH1 (show GNRH1 Antibodies) and GDF9 genes could serve as genetic markers for litter size in goat breeding.

  3. Mutation A959C in GDF9 gene has been associated with prolificacy.

  4. Expression levels of follicular GDF9 and total ovarian BMPR1B (show BMPR1B Antibodies) were not different between the Lezhi black goat and the Tibetan goat.

  5. These results provide further evidence that the GDF9 gene may be significantly correlated with high prolificacy in goats.

GDF9 Antigen Profile

Protein Summary

Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. Growth differentiation factor-9 (GDF9) is expressed in oocytes and is thought to be required for ovarian folliculogenesis. GDF9 is a member of the transforming growth factor-beta superfamily.

Gene names and symbols associated with GDF9

  • growth differentiation factor 9 (GDF9) antibody
  • growth differentiation factor 9 (gdf9) antibody
  • growth differentiation factor 9 (Gdf9) antibody
  • Gdf-9 antibody
  • zgc:123030 antibody

Protein level used designations for GDF9

growth and differentiation factor 9 , growth/differentiation factor 9 , GDF-9 , growth differentiation factor-9

GENE ID SPECIES
100072822 Equus caballus
497643 Danio rerio
2661 Homo sapiens
14566 Mus musculus
59304 Rattus norvegicus
404533 Gallus gallus
100313495 Canis lupus familiaris
414285 Sus scrofa
282574 Bos taurus
100328727 Oryctolagus cuniculus
100735066 Cavia porcellus
100860859 Capra hircus
100217402 Ovis aries
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