anti-Growth Factor Independent 1B Transcription Repressor (GFI1B) Antibodies

Essential transcriptional regulator necessary for development and differentiation of erythroid and megakaryocytic lineages. Additionally we are shipping GFI1B Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GFI1B 8328 Q5VTD9
GFI1B 311832  
GFI1B 14582 O70237
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Top anti-GFI1B Antibodies at antibodies-online.com

Showing 10 out of 33 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB Rabbit Anti-GFI1B Antibody Catalog Number: ARP30093 Paraffin Embedded Tissue: Human Heart Cellular Data: Myocardial cells Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X Rabbit Anti-GFI1B Antibody Catalog Number: ARP30093 Paraffin Embedded Tissue: Human Kidney Cellular Data: Epithelial cells of renal tubule and renal corpuscle Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$306.90
Details
Human Rabbit Un-conjugated WB GFI1B Antibody (C-term) (ABIN1881370) western blot analysis in HL-60,K562,U266 cell line and mouse spleen lysates (35 µg/lane). This demonstrates the GFI1B antibody detected the GFI1B protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of GFI1B expression in HEK293T (A), NS-1 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Cow Rabbit Un-conjugated IHC (p), WB   50 μg Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 7 to 9 Days
$698.50
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Cy5 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

GFI1B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GFI1B Antibodies

  1. Human Polyclonal GFI1B Primary Antibody for WB - ABIN1881370 : Rödel, Wagner, Zörnig, Niessing, Möröy: The human homologue (GFI1B) of the chicken GFI gene maps to chromosome 9q34.13-A locus frequently altered in hematopoietic diseases. in Genomics 1999 (PubMed)
    Show all 2 Pubmed References

More Antibodies against GFI1B Interaction Partners

Human Growth Factor Independent 1B Transcription Repressor (GFI1B) interaction partners

  1. High GFI1B expression is associated with small-cell lung cancer.

  2. Results demonstrate that alpha-delta platelet storage pool deficiency is associated with either a heterozygous mutation in GFI1B (de novo or familial) abrogating the binding of the zinc fingers with the promoter of its target genes, or by hypomorphic biallelic mutations leading to autosomal recessive inheritance.

  3. study demonstrates the significance of Gfi1b regulated Kindlin3-Talin1 expression in driving megakaryocytic differentiation and highlights the contribution of cytoskeletal agents in the developmental progression of these platelet progenitors

  4. Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

  5. SPI1 (show SPI1 Antibodies)-GFI1B transcriptional network is an important regulatory axis in acute myeloid leukemia (show BCL11A Antibodies) as well as in the development of erythroid versus myelomonocytic cell fate

  6. Gfi1b functions as a transcriptional repressor by recruiting histone-modifying enzymes to promoters and enhancers of target genes. Mutations are associated with certain bleeding disorders. Review.

  7. a mutation in GFI1B causes a platelet disorder; GFI1B has a role a critical regulator of platelet shape, number, and function

  8. results, supported by evidence from mouse models, identify GFI1 (show ZNF163 Antibodies) and GFI1B as prominent medulloblastoma oncogenes and implicate 'enhancer hijacking' as an efficient mechanism driving oncogene (show RAB1A Antibodies) activation in a childhood cancer

  9. TAL1 (show TAL1 Antibodies) is involved in regulating H3K27me3 variations in collaboration with GFI1B

  10. Silencing of both BCR-ABL (show ABL1 Antibodies) siRNA and GFI1B siRNA is associated with an additive antileukemic effect against K562 cells.

Zebrafish Growth Factor Independent 1B Transcription Repressor (GFI1B) interaction partners

  1. These findings suggest that Gfi1.1 plays a critical role in regulating the balance of embryonic erythroid and myeloid lineage determination, and is also required for the differentiation of lymphocytes and granulocytes during zebrafish embryogenesis.

Mouse (Murine) Growth Factor Independent 1B Transcription Repressor (GFI1B) interaction partners

  1. We conclude that Gfi1b controls major functions of megakaryocytes such as integrin-dependent cytoskeleton organization, spreading and migration through the regulation of PAK activity whereas the proplatelet formation defect in GFI1B-deficient megakaryocytes is due, at least partially, to an insufficient alpha-tubulin (show TUBA4A Antibodies) content.

  2. these results identify Rgs18 (show RGS18 Antibodies) as a new and crucial effector of Gfi1b that regulates downstream signaling and gene expression programs to orchestrate erythro-megakaryocytic lineage choices.

  3. Gfi1b is a regulator of embryonic globin expression and embryonic and adult erythroid maturation.

  4. results, supported by evidence from mouse models, identify GFI1 (show ZNF163 Antibodies) and GFI1B as prominent medulloblastoma oncogenes and implicate 'enhancer hijacking' as an efficient mechanism driving oncogene (show RAB1A Antibodies) activation in a childhood cancer

  5. Gfi1 (show ZNF163 Antibodies) and gfi1b repress rag transcription in plasmacytoid dendritic cells in vitro.

  6. GFI1B, EVI5 (show EVI5 Antibodies), MYB (show MYB Antibodies) are additional mouse genes that cooperate with the human BCL6 (show BCL6 Antibodies) gene to promote the development of lymphomas.

  7. There is direct yet differential regulation of meis1 (show MEIS1 Antibodies) transcription by Gfi1b in distinct hematopoietic lineages.

  8. GFI1 (show ZNF163 Antibodies) and GFI1B are able to trigger, in the absence of RUNX1 (show RUNX1 Antibodies), the down-regulation of endothelial markers and the formation of round cells, a morphologic change characteristic of endothelial to hematopoietic transition.

  9. Gfi family members are essential for normal B cell development and play an important role in modulating expression of the V(D)J recombinase (show RAG1 Antibodies).

  10. The transcription factor Gfi1b defines the brush cell lineage and its progenitors, and with Hes1 and Atoh1 (show ATOH1 Antibodies) forms a fate-determining Notch (show NOTCH1 Antibodies) signaling driven ternary switch in the developing intestinal epithelium.

GFI1B Antigen Profile

Protein Summary

Essential transcriptional regulator necessary for development and differentiation of erythroid and megakaryocytic lineages. Alters histone methylation by recruiting histone methyltransferase to target genes promoters. Plays a role in heterochromatin formation.

Gene names and symbols associated with GFI1B

  • growth factor independent 1B transcription repressor (GFI1B) antibody
  • growth factor independent 1B transcription repressor (Gfi1b) antibody
  • growth factor independent 1B transcription repressor (gfi1b) antibody
  • Zinc finger protein Gfi-1b (gfi1b) antibody
  • growth factor independent 1ab (gfi1ab) antibody
  • growth factor independent 1B (Gfi1b) antibody
  • GFI antibody
  • Gfi-1B antibody
  • gfi1 antibody
  • gfi1.2 antibody
  • gfi1b antibody
  • MGC80648 antibody
  • znf544 antibody

Protein level used designations for GFI1B

growth factor independent 1B (potential regulator of CDKN1A, translocated in CML) , growth factor independent 1B transcription repressor , growth factor independent protein 1B , potential regulator of CDKN1A translocated in CML , zinc finger protein Gfi-1b , growth factor-independent protein 1B , zinc finger protein 544 , growth factor independent 1B-like protein , Zinc finger protein Gfi-1b , growth factor independent 1 , growth factor independent 1.2 , growth factor independent 1b , zinc finger protein Gfi-1

GENE ID SPECIES
491281 Canis lupus familiaris
473080 Pan troglodytes
8328 Homo sapiens
311832 Rattus norvegicus
395977 Gallus gallus
446835 Xenopus laevis
537773 Bos taurus
100195098 Salmo salar
798697 Danio rerio
14582 Mus musculus
100514698 Sus scrofa
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