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anti-Growth Factor Receptor-Bound Protein 14 (GRB14) Antibodies

The product of GRB14 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. Additionally we are shipping GRB14 Kits (25) and GRB14 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GRB14 50915 Q9JLM9
GRB14 58844 O88900
GRB14 2888 Q14449
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Top anti-GRB14 Antibodies at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Host: Rabbit  Target Name: Grb14  Sample Tissue: Rat Testis lysates  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HuvEc/COLO/MCF-7 cells, using GRB14 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated IP, IHC, WB Immunohistochemical analysis of GRB14 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of GRB14 expression in MOLT4 (A), COLO205 (B) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human kidney labeled with Anti-GRB 14 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 14 to 21 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Rat Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 8 to 10 Days
$566.50
Details
Rat Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details

GRB14 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


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Rat (Rattus) ,


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Human , , ,


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More Antibodies against GRB14 Interaction Partners

Mouse (Murine) Growth Factor Receptor-Bound Protein 14 (GRB14) interaction partners

  1. The phosphorylation status of the BPS region of Grb14 determines the positive or negative role it will play in insulin receptor (show INSR Antibodies) signaling.

  2. Data show that Grb14 inhibits the activity of PTP1B (show PTPN1 Antibodies) in retina in a phosphorylation-regulated (show PHAX Antibodies) manner, and that rhodopsin (show RHO Antibodies)-regulated Src kinase (show CSK Antibodies) activation in retina leads to the phosphorylation of Grb14.

  3. Grb14 is a normal physiological modulator of CNG (show CNGA1 Antibodies) channel function in vivo.

  4. Grb14 functions in vivo as a tissue-specific modulator of insulin (show INS Antibodies) action, most likely via repression of IR-mediated IRS-1 (show IRS1 Antibodies) tyrosine phosphorylation

  5. regulation of Grb14 expression in adipose tissue may play a physiological role in insulin (show INS Antibodies) sensitivity

  6. Grb14 exerts a dual role on the regulation by insulin (show INS Antibodies) of hepatic metabolism. It inhibits insulin receptor (show INSR Antibodies) catalytic activity, and as a sterol regulatory element binding protein (show CNBP Antibodies)-1c maturation.

  7. These results demonstrate that Grb14 can undergo subcellular redistribution upon illumination and suggest that rhodopsin (show RHO Antibodies) photoexcitation may trigger signaling events alternative to the classical transducin (show GNAT1 Antibodies) activation.

  8. Grb10 (show GRB10 Antibodies) and Grb14 have roles in regulation of insulin (show INS Antibodies) signaling and glucose homeostasis

Human Growth Factor Receptor-Bound Protein 14 (GRB14) interaction partners

  1. Phosphorylation of Grb14 BPS domain by GSK-3 (show GSK3b Antibodies) correlates with complex forming of Grb14 and insulin receptor (show INSR Antibodies).

  2. Genes within recently identified loci associated with waist-hip ratio (WHR) exhibit fat depot-specific mRNA expression, which correlates with obesity-related traits. Adipose tissue (AT) mRNA expression of 6 genes (TBX15 (show TBX15 Antibodies)/WARS2 (show WARS2 Antibodies), STAB1 (show STAB1 Antibodies), PIGC (show PIGC Antibodies), ZNRF3 (show ZNRF3 Antibodies), GRB14

  3. Modulation of mouse rod photoreceptor responses by Grb14 protein.

  4. ANKRD55 rs459193 and GRB14 rs13389219 associate with insulin (show INS Antibodies) resistance.

  5. Studies indicate that insulin receptor (IR (show INSR Antibodies)) and IGF Type 1 Receptor (IGFR) have been identified as important partners of Grb10 (show GRB10 Antibodies)/14 and SH2B1 (show SH2B1 Antibodies)/B2 adaptors.

  6. Grb14 is the first negative regulator of CEACAM3 (show CEACAM3 Antibodies)-initiated bacterial phagocytosis and might help to focus granulocyte responses to the subcellular sites of pathogen-host cell contact

  7. A new role for Grb14 in finely tuning receptor signaling and modulating thyroid cancer progression.

  8. Grb14 was recruited to FGFR1 (show FGFR1 Antibodies) into a trimeric complex containing also phospholipase C (show PLC Antibodies) gamma

  9. serves as an adaptor protein to recruit 3-phosphoinositede-dependent kinase-1 to activated insulin receptor (show INSR Antibodies), thus promoting Akt (show AKT1 Antibodies) phosphorylation and transduction of the insulin (show INS Antibodies) signal

  10. regulation of Grb14 expression levels in response to hormonal stimuli, and are consistent with its role as a repressor of insulin (show INS Antibodies) signaling where it is induced as a negative feedback mechanism.

Cow (Bovine) Growth Factor Receptor-Bound Protein 14 (GRB14) interaction partners

  1. These findings suggest that Grb14 may play a regulatory role in granulosa cells during follicular deviation in cattle.

  2. The growth factor receptor (show RYK Antibodies) bound protein (Grb) 14 NPXY motif could be acting as a dominant negative for insulin receptor (show INSR Antibodies) substrate (IRS)-1 (show IRS1 Antibodies) functions in the retina.

  3. Grb14 contains a phosphorylated insulin receptor interacting domain between the pleckstrin homolog) and SH2 domains that binds to and forms a specific complex with the cytoplasmic domain of IRbeta

GRB14 Antigen Profile

Protein Summary

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Transcript variants have been reported for this gene, but their full-length natures have not been determined to date.

Gene names and symbols associated with GRB14

  • growth factor receptor-bound protein 14 (GRB14) antibody
  • growth factor receptor-bound protein 14 (grb14) antibody
  • growth factor receptor bound protein 14 (Grb14) antibody
  • growth factor receptor-bound protein 14 (Grb14) antibody
  • growth factor receptor-bound protein 14 (LOC100341938) antibody
  • AI505286 antibody
  • GRB14 antibody

Protein level used designations for GRB14

growth factor receptor-bound protein 14 , growth factor receptor-bound protein 14-like , GRB14 adapter protein , growth factor receptor bound protein 14

GENE ID SPECIES
459695 Pan troglodytes
100390507 Callithrix jacchus
100447515 Pongo abelii
100561062 Anolis carolinensis
50915 Mus musculus
58844 Rattus norvegicus
2888 Homo sapiens
100718629 Cavia porcellus
100514075 Sus scrofa
497029 Bos taurus
100861137 Capra hircus
424183 Gallus gallus
101105217 Ovis aries
100341938 Oryctolagus cuniculus
478770 Canis lupus familiaris
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